USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair
Journal
Nucleic Acids Research
Triggering apoptosis by oroxylin A through caspase-8 activation and p62/SQSTM1 proteolysis
Rac GTPase activating protein 1 promotes gallbladder cancer via binding DNA ligase 3 to reduce apoptosis
Smart dual responsive nanocarriers with reactive oxygen species amplification assisted synergistic chemotherapy against prostate cancer
Journal
Journal of colloid and interface science
Cyclodextrin-based supramolecular nanoparticles break the redox balance in chemodynamic therapy-enhanced chemotherapy
Journal
Journal of colloid and interface science
NCAPD2 inhibits autophagy by regulating Ca2+/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer
A novel kinase inhibitor, LZT-106, downregulates Mcl-1 and sensitizes colorectal cancer cells to BH3 mimetic ABT-199 by targeting CDK9 and GSK-3β signaling
Epigenetic inhibition of CTCF by HN1 promotes dedifferentiation and stemness of anaplastic thyroid cancer
Development of Strigolactones as Novel Autophagy/Mitophagy Inhibitors against Colorectal Cancer Cells by Blocking the AutophagosomeLysosome Fusion
Journal
Journal of medicinal chemistry
TKT-PARP1 axis induces radioresistance by promoting DNA double-strand break repair in hepatocellular carcinoma - PMC
Hyperoside and Quercitrin in Houttuynia cordata Extract Attenuate UVB-Induced Human Keratinocyte Cell Damage and Oxidative Stress via Modulation of MAPKs and Akt Signaling Pathway
Journal
Antioxidants (Basel, Switzerland)
Involvement of p53 acetylation in growth suppression of Cutaneous T-cell lymphomas induced by HDAC inhibition
Journal
The Journal of Investigative Dermatology
LW-213 induces cell apoptosis in human cutaneous T-cell lymphomas by activating PERK–eIF2α–ATF4–CHOP axis
Journal
Acta Pharmacol Sin
Induction of cell cycle arrest and apoptosis by CPUC002 through stabilization of p53 and suppression of STAT3 signaling pathway in multiple myeloma
Topotecan induces apoptosis via ASCT2 mediated oxidative stress in gastric cancer.
Species
Homo sapiens, Mus musculus
Protective effects of E Se tea extracts against alcoholic fatty liver disease induced by high fat/alcohol diet: In vivo biological evaluation and molecular docking study
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Extracellular HMGB1 interacts with RAGE and promotes chemoresistance in acute leukemia cells
Journal
Cancer cell international
Inhibition of mitochondrial carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances sensitivity to temozolomide in malignant glioma
Targeted Co-Delivery of Gefitinib and Rapamycin by Aptamer-Modified Nanoparticles Overcomes EGFR-TKI Resistance in NSCLC via Promoting Autophagy - PMC
Journal
International journal of molecular sciences
Diclofenac Sensitizes Signet Ring Cell Gastric Carcinoma Cells to Cisplatin by Activating Autophagy and Inhibition of Survival Signal Pathways - PMC
Journal
International journal of molecular sciences
Deficient or R273H and R248W Mutations of p53 Promote Chemoresistance to 5-FU via TCF21/CD44 Axis-Mediated Enhanced Stemness in Colorectal Carcinoma.
Journal
Frontiers in cell and developmental biology
Antiviral Immunotoxin Against Bovine herpesvirus-1: Targeted Inhibition of Viral Replication and Apoptosis of Infected Cell
Journal
Frontiers in microbiology
15, 16-Dihydrotanshinone I Inhibits Hemangiomas through Inducing Pro-apoptotic and Anti-angiogenic Mechanisms in Vitro and in Vivo.
Journal
Frontiers in Pharmacology
Scoparone Improves Nonalcoholic Steatohepatitis Through Alleviating JNK/Sab Signaling Pathway-Mediated Mitochondrial Dysfunction
Journal
Frontiers in pharmacology
Quercetin Attenuates Cardiac Hypertrophy by Inhibiting Mitochondrial Dysfunction Through SIRT3/PARP-1 Pathway
Adipose-derived mesenchymal stem cells-derived exosome-mediated microRNA-342-5p protects endothelial cells against atherosclerosis
ESR1 Regulates the Obesity- and Metabolism-Differential Gene MMAA to Inhibit the Occurrence and Development of Hepatocellular Carcinoma - PMC
Journal
Frontiers in oncology
Twist1 Rescue Calcium Overload And Apoptosis Induced by Inflammatory Microenvironment in S. Aureus-Induced Osteomyelitis
Journal
International immunopharmacology
FTO blocks RNA translational activity via the loss of N6methyladenosine methylation at 5 UTR regulated by RBM5 in cisplatinresistant NSCLC
Journal
Journal of cellular physiology
Glycolysis inhibition and apoptosis induction in human prostate cancer cells by FV-429-mediated regulation of AR-AKT-HK2 signaling network
Metabolomics Analysis of the Prefrontal Cortex in a Rat Chronic Unpredictable Mild Stress Model of Depression
Journal
Frontiers in psychiatry
Adropin attenuates pancreatitis-associated lung injury through PPAR phosphorylation-related macrophage polarization - PMC
Journal
International journal of molecular medicine
Discovery of linear unnatural peptides as potent mutant isocitrate dehydrogenase 1 inhibitors by Ugi reaction
Low doses of niclosamide and quinacrine combination yields synergistic effect in melanoma via activating autophagy-mediated p53-dependent apoptosis
Journal
Translational oncology
LncRNA MT1JP plays a protective role in intrahepatic cholangiocarcinoma by regulating miR-18a-5p/FBP1 axis
Giardia duodenalis Induces Apoptosis in Intestinal Epithelial Cells via Reactive Oxygen Species-Mediated Mitochondrial Pathway In Vitro
Species
Giardia duodenalis
Fusaric acid inhibits proliferation and induces apoptosis through triggering endoplasmic reticulum stress in MCF-7 human breast cancer cells
Journal
Mycotoxin research
Inhibition of p66Shc attenuates retinal ischemia-reperfusion injury-induced damage by activating the akt pathway
Journal
Experimental eye research
NVP-BEZ235 synergizes cisplatin sensitivity in osteosarcoma
Indocyanine Green Based Photodynamic Therapy for Keloids: Fundamental Investigation and Clinical Improvement
Journal
Photodiagnosis and photodynamic therapy
Effects of intracellular iron overload on cell death and identification of potent cell death inhibitors.
Journal
Close affiliations Biochemical and Biophysical Research Communications
KBTBD2 promotes proliferation and migration of gastric cancer via activating EGFR signaling pathway
Journal
Pathology, research and practice
Species
Homo sapiens,Mus musculus
Diosgenin inhibits the proliferation of gastric cancer cells via inducing mesoderm posterior 1 down-regulation-mediated alternative reading frame expression
Structures, chemical conversions, and cytotoxicity of tricholopardins C and D, two tricholoma triterpenoids from the wild mushroom Tricholoma pardinum
Journal
Natural products and bioprospecting