Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission
Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability
Journal
Nature communications
Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells
Co-targeting BET bromodomain BRD4 and RAC1 suppresses growth, stemness and tumorigenesis by disrupting the c-MYC-G9a-FTH1axis and downregulating HDAC1 in molecular subtypes of breast cancer
NOX4 blockade suppresses titanium nanoparticle-induced bone destruction via activation of the Nrf2 signaling pathway
Journal
Journal of nanobiotechnology
Iron deficiency exacerbates cisplatin-or rhabdomyolysis-induced acute kidney injury through promoting iron-catalyzed oxidative damage
Journal
Free Radic Biol Med
Up-regulation of Nrf2/HO-1 and inhibition of TGF-β1/Smad2/3 signaling axis by daphnetin alleviates transverse aortic constriction-induced cardiac remodeling in mice
Journal
Free radical biology & medicine
Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress - PMC
Journal
Antioxidants (Basel, Switzerland)
Species
Mus musculus, Rattus norvegicus
AIP1 suppresses neovascularization by inhibiting the NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn model
Journal
Cell communication and signaling : CCS
Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cells
Journal
Acta Pharmacol Sin
Daidzein mitigates myocardial injury in streptozotocin-induced diabetes in rats
Pterostilbene prevents LPS-induced early pulmonary fibrosis by suppressing oxidative stress, inflammation and apoptosis in vivo
Metformin Attenuates TGF-1-Induced Fibrosis in Salivary Gland: A Preliminary Study - PMC
Journal
International journal of molecular sciences
Species
Homo sapiens, Rattus norvegicus
The Neuroprotective Effect of Astaxanthin on Pilocarpine-Induced Status Epilepticus in Rats.
Journal
Frontiers in Cellular Neuroscience
Dipeptidyl peptidase-4 inhibition improves endothelial senescence by activating AMPK/SIRT1/Nrf2 signaling pathway
Journal
Biochemical Pharmacology
Species
Homo sapiens,Rattus norvegicus
Hepatitis E Virus Induces Brain Injury Probably Associated With Mitochondrial Apoptosis.
Journal
Frontiers in Cellular and Infection Microbiology
N-Acetyl Cysteine Ameliorates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease and Intracellular Triglyceride Accumulation by Preserving Mitochondrial Function
Role of PDK4 in insulin signaling pathway in periadrenal adipose tissue of pheochromocytoma patients
Journal
Endocrine-related cancer
Daidzein ameliorates peripheral neuropathy in Sprague Dawley rats - PMC
Journal
Frontiers in pharmacology
Adipose-specific BMP and Activin Membrane-Bound Inhibitor (BAMBI) Deletion Promotes Adipogenesis by Accelerating ROS Production
Andrographolide attenuates epithelial‐mesenchymal transition induced by TGF‐β1 in alveolar epithelial cells
Oridonin attenuates LPS-induced early pulmonary fibrosis by regulating impaired autophagy, oxidative stress, inflammation and EMT
Journal
European journal of pharmacology
Hesperetin relieves cisplatin-induced acute kidney injury by mitigating oxidative stress, inflammation and apoptosis.
Journal
Chemico-biological interactions
MiR-196a-5p hinders vascular smooth muscle cell proliferation and vascular remodeling via repressing BACH1 expression - PMC
Journal
Scientific reports
Participation of follicular superoxides, inflammatory modulators, and endocrine factors in zebrafish (Danio rerio) ovulation: Cross-talk between PKA and MAPK
Journal
Molecular and cellular endocrinology
Increased oxidative stress, inflammation and fibrosis in perirenal adipose tissue of patients with cortisol-producing adenoma.