Suppressing Mesenchymal Stromal Cell Ferroptosis Via Targeting a MetabolismEpigenetics Axis Corrects their Poor Retention and Insufficient Healing Benefits in
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
A nuclear long non-coding RNA LINC00618 accelerates ferroptosis in a manner dependent upon apoptosis
Journal
Molecular therapy : the journal of the American Society of Gene Therapy
IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE 2
Journal
Journal of experimental & clinical cancer research : CR
A DihydroartemisininLoaded Nanoreactor Motivates AntiCancer Immunotherapy by SynergyInduced Ferroptosis to Activate Cgas/STING for Reprogramming of
Journal
Advanced healthcare materials
Ferroptosis is critical for phthalates driving the blood-testis barrier dysfunction via targeting transferrin receptor - PMC
Estradiol-mediated small GTP-binding protein GDP dissociation stimulator induction contributes to sex differences in resilience to ferroptosis in takotsubo
Ignored role of polyphenol in boosting reactive oxygen species generation for polyphenol/chemodynamic combination therapy - PMC
Journal
Materials today. Bio
Multifunctional annulus fibrosus matrix prevents disc-related pain via inhibiting neuroinflammation and sensitization
Journal
Acta biomaterialia
Cr (VI) induces ferroptosis in DF-1 cells by simultaneously perturbing iron homeostasis of ferritinophagy and mitophagy
Journal
The Science of the total environment
PUFAs add fuel to Crohns disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation - PMC
Species
Homo sapiens, Mus musculus
A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin
Journal
Journal of nanobiotechnology
Species
Homo sapiens, Mus musculus
Pou3f1 mediates the effect of Nfatc3 on ulcerative colitis-associated colorectal cancer by regulating inflammation - PMC
Journal
Cellular & molecular biology letters
Pou3f1 mediates the effect of Nfatc3 on ulcerative colitis-associated colorectal cancer by regulating inflammation - PMC
Journal
Cellular & molecular biology letters
N-Acetyl-l-cysteine restores reproductive defects caused by Ggt1 deletion in mice
Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis
Journal
Free radical biology & medicine
Species
Homo sapiens, Mus musculus
PM2. 5 contributed to pulmonary epithelial senescence and ferroptosis by regulating USP3-SIRT3-P53 axis
Journal
Free radical biology & medicine
Targeting antioxidant factor Nrf2 by raffinose ameliorates lipid dysmetabolism-induced pyroptosis, inflammation and fibrosis in NAFLD
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Discovery of Novel Pterostilbene Derivatives That Might Treat Sepsis by Attenuating Oxidative Stress and Inflammation through Modulation of MAPKs/NF-κB Signaling Pathways
Journal
Antioxidants (Basel)
Hydroxytyrosol Ameliorates Intervertebral Disc Degeneration and Neuropathic Pain by Reducing Oxidative Stress and Inflammation - PMC
Journal
Oxidative medicine and cellular longevity
Methionine alleviates heat stress-induced ferroptosis in bovine mammary epithelial cells through the Nrf2 pathway
Journal
Ecotoxicology and environmental safety
Ammonia-induced excess ROS causes impairment and apoptosis in porcine IPEC-J2 intestinal epithelial cells
Journal
Ecotoxicology and environmental safety
Persistent ferroptosis promotes cervical squamous intraepithelial lesion development and oncogenesis by regulating KRAS expression in patients with high risk-HPV infection
Journal
Cell death discovery
Design, synthesis, and SAR study of novel 4,5-dihydropyrazole-Thiazole derivatives with anti-inflammatory activities for the treatment of sepsis
Synthesis of 1, 3, 5-Triphenyl-1, 2, 4-Triazole Derivatives and Their Neuroprotection by Anti-Oxidative Stress and Anti-Inflammation and Protecting BBB
Journal
European journal of medicinal chemistry
Timosaponin B-II alleviates osteoarthritis-related inflammation and extracellular matrix degradation through inhibition of mitogen-activated protein kinases and nuclear factor-κB pathways in vitro
Suppression of lncRNA Gm47283 attenuates myocardial infarction via miR-706 / Ptgs2 /ferroptosis axis
The Anti-Inflammatory Effect of Bovine Bone-Gelatin-Derived Peptides in LPS-Induced RAW264.7 Macrophages Cells and Dextran Sulfate Sodium-Induced C57BL/6 Mice
Anti-Inflammatory and Antioxidant Effects of Anthocyanins of Trifolium pratense (Red Clover) in Lipopolysaccharide-Stimulated RAW-267.4 Macrophages
Species
Trifolium pratense
Structural modification based on the diclofenac scaffold: Achieving reduced colitis side effects through COX-2/NLRP3 selective inhibition
Journal
European journal of medicinal chemistry
Melatonin Prevents Chondrocyte Matrix Degradation in Rats with Experimentally Induced Osteoarthritis by Inhibiting Nuclear Factor-κB via SIRT1 - PMC
Protective effects of E Se tea extracts against alcoholic fatty liver disease induced by high fat/alcohol diet: In vivo biological evaluation and molecular docking study
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Anti-Inflammatory Effect of a Polyphenol-Enriched Fraction from Acalypha wilkesiana on Lipopolysaccharide-Stimulated RAW 264.7 Macrophages and Acetaminophen-Induced Liver Injury in Mice.
Journal
Oxidative Medicine and Cellular Longevity
Co-delivery of Gentiopicroside and Thymoquinone Using Electrospun m-PEG/PVP Nanofibers: In-Vitro and In Vivo Studies for Antibacterial Wound Dressing in …
Journal
International journal of pharmaceutics
Oxymatrine loaded nitric oxide-releasing liposomes for the treatment of ulcerative colitis
Ganoderic acid improves 5-fluorouracil-induced cognitive dysfunction in mice
Investigation of the active components and mechanisms of Schisandra chinensis in the treatment of asthma based on a network pharmacology approach and experimental validation
Species
Rattus norvegicus,Schisandra chinensis
The preventive effect and underlying mechanism of Rhus chinensis Mill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice
The mechanism of ginger and its processed products in the treatment of estradiol valerate coupled with oxytocin-induced dysmenorrhea in mice via regulating …
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-B/NLRP3/GSDMD Pathway - PMC
Journal
International journal of molecular sciences
Effects of Curcumin on Oxidative Stress and Ferroptosis in Acute Ammonia Stress-Induced Liver Injury in Gibel Carp (Carassius gibelio) - PMC
Journal
International journal of molecular sciences
The Ameliorative Role of Lico A on Aflatoxin B1-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway
Journal
Journal of agricultural and food chemistry
Insight into Fucoidan-Based PEGylated PLGA Nanoparticles Encapsulating Methyl Anthranilic Acid: In Vitro Evaluation and In Vivo Anti-Inflammatory Study - PMC
Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats
Journal
Frontiers in pharmacology
Propofol inhibits neuroinflammation and metabolic reprogramming in microglia in vitro and in vivo
- PMC
Journal
Frontiers in pharmacology
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway - PMC
Journal
Frontiers in pharmacology
Exploring the potential mechanism of Fritiliariae Irrhosae Bulbus on ischemic stroke based on network pharmacology and experimental validation - PMC
Journal
Frontiers in pharmacology
Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage - PMC
Journal
Frontiers in pharmacology
Platelet-rich plasma ameliorates lipopolysaccharide-induced cardiac injury by inflammation and ferroptosis regulation - PMC
Journal
Frontiers in pharmacology
α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback
Journal
Frontiers in pharmacology
Capsaicin alleviates doxorubicin-induced acute myocardial injury by regulating iron homeostasis and PI3K-Akt signaling pathway - PMC
Capsaicin alleviates doxorubicin-induced acute myocardial injury by regulating iron homeostasis and PI3K-Akt signaling pathway - PMC
Exploring the Mechanism of Hawthorn Leaves Against Coronary Heart Disease Using Network Pharmacology and Molecular Docking - PMC
Journal
Frontiers in cardiovascular medicine
Exosomes derived from pericardial adipose tissues attenuate cardiac remodeling following myocardial infarction by Adipsin-regulated iron homeostasis - PMC
Journal
Frontiers in cardiovascular medicine
Rosiglitazone retards the progression of iron overload-induced osteoarthritis by impeding chondrocyte ferroptosis - PMC
Liproxstatin-1 Attenuates Morphine Tolerance through Inhibiting Spinal Ferroptosis-like Cell Death
Journal
ACS chemical neuroscience
MiR-144-5p limits experimental abdominal aortic aneurysm formation by mitigating M1 macrophage-associated inflammation: Suppression of TLR2 and OLR1
Journal
Journal of Molecular and Cellular Cardiology
Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation
Journal
Vascular Pharmacology
Thymopentin (TP-5) prevents lipopolysaccharide-induced neuroinflammation and dopaminergic neuron injury by inhibiting the NF-κB/NLRP3 signaling pathway
Journal
International immunopharmacology
Cytoplasmic HMGB1 induces renal tubular ferroptosis after ischemia/reperfusion
Journal
International immunopharmacology
Albiflorin ameliorates inflammation and oxidative stress by regulating the NF-κB/NLRP3 pathway in Methotrexate-induced enteritis
Journal
International immunopharmacology
Stevioside targets the NF-κB and MAPK pathways for inhibiting inflammation and apoptosis of chondrocytes and ameliorates osteoarthritis in vivo
Journal
International immunopharmacology
Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis
Journal
Molecular neurobiology
Quercetin Modulates Ferroptosis via the SIRT1/Nrf-2/HO-1 Pathway and Attenuates Cartilage Destruction in an Osteoarthritis Rat Model - PMC
Journal
International journal of molecular sciences
Lycopene ameliorates atrazine-induced spatial learning and memory impairments by inhibiting ferroptosis in the hippocampus of mice
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Copper induces microglia-mediated neuroinflammation through ROS/NF-κB pathway and mitophagy disorder
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
The Protective Effect and Mechanism of a Phytochemical Extract from the Wild Vegetable Shutou (Crateva unilocularis Buch.) against Acetaminophen-Induced Liver Injury in Mice - PMC
Journal
Foods (Basel, Switzerland)
The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for mitochondrial function
Journal
The Journal of biological chemistry
Inula japonica ameliorated bleomycin-induced pulmonary fibrosis via inhibiting soluble epoxide hydrolase
Journal
Bioorganic chemistry
Discovery of novel dihydropyrazole-stilbene derivatives for ameliorating heart failure through modulation of p38/NF-kB signaling pathway
Journal
Bioorganic chemistry
A novel danshensu derivative ameliorates experimental colitis by modulating NADPH oxidase 4‐dependent NLRP3 inflammasome activation
Overexpression of c-Jun inhibits erastin-induced ferroptosis in Schwann cells and promotes repair of facial nerve function
Journal
Journal of cellular and molecular medicine
Fabrication of Celecoxib PVP Microparticles Stabilized by Gelucire 48/16 via Electrospraying for Enhanced Anti-Inflammatory Action - PMC
Journal
Pharmaceuticals (Basel, Switzerland)
Rhizoma Smilacis Glabrae inhibits pathogen-induced upper genital tract inflammation in rats through suppression of NF-B pathway
Journal
Journal of ethnopharmacology
Systems pharmacology-based dissection of mechanisms of Tibetan medicinal compound Ruteng as an effective treatment for collagen-induced arthritis rats
Journal
Journal of ethnopharmacology
Species
Boswellia carterii
Study on the effect of active components of Schisandra chinensis on liver injury and its mechanisms in mice based on network pharmacology
In vitro and in vivo anti-inflammatory effects of different extracts from Epigynum auritum through down-regulation of NF-κB and MAPK signaling pathways
Isorhynchophylline ameliorates the progression of osteoarthritis by inhibiting the NF-B pathway
Journal
European journal of pharmacology
Ferroptosis triggered by dihydroartemisinin facilitates chlorin e6 induced photodynamic therapy by inhibiting GPX4 and enhancing ROS
Journal
European journal of pharmacology
Oxidative stress and ferroptosis involved in 2-ethylhexyl diphenyl phosphate-induced hepatotoxicity in chicken
Journal
Chemico-biological interactions
Novel anti-arthritic mechanisms of trans-cinnamaldehyde against complete Freund's adjuvant-induced arthritis in mice: involvement of NF-кB/TNF-α and IL-6/IL-23/ IL-17 pathways in the immuno-inflammatory responses
Journal
Inflammopharmacology
The emerging coloprotective effect of sildenafil against ulcerative colitis in rats via exerting counterbalance between NF-κB signaling and Nrf-2/HO-1 pathway - PMC
Journal
Inflammopharmacology
Mitochondria-Related Ferroptosis Drives Cognitive Deficits in Neonatal Mice Following Sevoflurane Administration - PMC
Journal
Frontiers in medicine
Elucidation of the Metabolite Profile of Yucca gigantea and Assessment of Its Cytotoxic, Antimicrobial, and Anti-Inflammatory Activities
Journal
Molecules (Basel, Switzerland)
Naringin Exhibited Therapeutic Effects against DSS-Induced Mice Ulcerative Colitis in Intestinal Barrier-Dependent Manner
Ethanol Extract of Rosa laevigata Michx. Fruit Inhibits Inflammatory Responses through NF-B/MAPK Signaling Pathways via AMPK Activation in RAW 264.7 Macrophages - PMC
Journal
Molecules (Basel, Switzerland)
COX-2 is required to mediate crosstalk of ROS-dependent activation of MAPK/NF-κB signaling with pro-inflammatory response and defense-related NO enhancement during challenge of macrophage-like cell line with Giardia duodenalis
Journal
PLoS neglected tropical diseases
Total Flavonoids of Rhizoma Drynariae Treat Osteoarthritis by Inhibiting Arachidonic Acid Metabolites Through AMPK/NFB Pathway - PMC
Journal
Journal of inflammation research
c-di-GMP induces COX-2 expression in macrophages in a STING-independent manner
Journal
ACS chemical biology
Chronic Polystyrene Microplastic Exposure Reduces Testosterone Levels in Mice through Mitochondrial Oxidative Stress and BAX/BCL2-Mediated Apoptosis - PMC
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent
The effect of inhibiting hindbrain A2 noradrenergic neurons by 6-Hydroxydopamine on lipopolysaccharide-treated male rats autistic animal model - PMC
Journal
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Blockade of Store-operated Calcium Entry Sensitizes Breast Cancer Cells to Cisplatin Therapy via Modulating Inflammatory Response
Journal
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Oridonin Inhibits Mycobacterium marinum Infection-Induced Oxidative Stress In Vitro and In Vivo - PMC
Journal
Pathogens (Basel, Switzerland)
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway
Sulforaphane Inhibits Oxidative Stress and May Exert Anti-Pyroptotic Effects by Modulating NRF2/NLRP3 Signaling Pathway in Mycobacterium tuberculosis-Infected Macrophages - PMC
Syringaldehyde Exhibits Antibacterial and Antioxidant Activities against Mycobacterium marinum Infection - PMC
Possible role of annexin A1/FPR2 pathway in COX2/NLRP3 inflammasome regulation in alveolar bone cells of estrogendeficient female rats with diabetes mellitus
Journal
Journal of periodontology
UBE2L3 promotes squamous cell carcinoma progression in the oral cavity and hypopharynx via activating the NF‐κB signaling by increasing IκBα degradation
Journal
Cell biology international
Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses
Journal
Toxicol Appl Pharmacol
Protective Effect of Anwulignan on Gastric Injury Induced by Indomethacin in Mice
Journal
The Journal of pharmacology and experimental therapeutics
Puerarin attenuates cadmium-induced hepatic lipid metabolism disorder by inhibiting oxidative stress and inflammation in mice
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine
Journal
Drug Des Devel Ther
MiR-1909-5p targeting GPX4 affects the progression of aortic dissection by modulating nicotine-induced ferroptosis
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ferroptosis mediated DSS-induced ulcerative colitis associated with Nrf2/HO-1 signaling pathway
Anti-inflammation of hydrogenated isoflavones in LPS-stimulated RAW264. 7 cells via inhibition of NF-B and MAPK signaling pathways
Journal
Molecular immunology
Species
Homo sapiens,Mus musculus
HBx induced upregulation of FATP2 promotes the development of hepatic lipid accumulation
Journal
Experimental cell research
Dexamethasone induces aberrant macrophage immune function and apoptosis
Species
Homo sapiens, Mus musculus
Syringin protects against colitis by ameliorating inflammation
Journal
Archives of Biochemistry and Biophysics
Dauricine negatively regulates lipopolysaccharide- or cecal ligation and puncture-induced inflammatory response via NF-κB inactivation.
Journal
Archives of biochemistry and biophysics
Tectoridin alleviates caerulein-induced severe acute pancreatitis by targeting ERK2 to promote macrophage M2 polarization
Journal
Archives of biochemistry and biophysics
Participation of follicular superoxides, inflammatory modulators, and endocrine factors in zebrafish (Danio rerio) ovulation: Cross-talk between PKA and MAPK
Journal
Molecular and cellular endocrinology
Decreased thioredoxin reductase 3 expression promotes nickel‐induced damage to cardiac tissue via activating oxidative stress‐induced apoptosis and inflammation
Journal
Environmental toxicology
Role of PERK-Mediated Endoplasmic Reticulum Stress in Ferroptosis Caused by Hexavalent Chromium in Chicken Hepatocytes
Journal
Biological trace element research
Selenium relieves oxidative stress, inflammation, and apoptosis within spleen of chicken exposed to mercuric chloride
Dietary Iron Overload Triggers Hepatic Metabolic Disorders and Inflammation in Laying Hen
Journal
Biological trace element research
Taxifolin protects against doxorubicin-induced cardiotoxicity and ferroptosis by adjusting microRNA-200a-mediated Nrf2 signaling pathway - PMC
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition - PMC
The Anti-Apoptotic Role of COX-2 during In Vitro Infection of Human Intestinal Cell Line by Giardia duodenalis and The Potential Regulators
Journal
Infection and immunity
Emodin suppresses oxaliplatininduced neuropathic pain by inhibiting COX2/NFB mediated spinal inflammation
Journal
Journal of biochemical and molecular toxicology
Synthesis of nature product kinsenoside analogues with anti-inflammatory activity
Journal
Bioorganic & medicinal chemistry
Suffrutines A and B Inhibit the Expression of Inflammatory Mediators in LPS-Induced RAW264. 7 Cells by Suppressing the NF-B Signaling Pathway
In vitro and in silico analysis of ‘Taikong blue lavender essential oil in LPS-induced HaCaT cells and RAW264.7 murine macrophages - PMC
Journal
BMC complementary medicine and therapies
Species
Homo sapiens, Mus musculus
Resveratrol ameliorates oxaliplatin-induced neuropathic pain via anti-inflammatory effects in rats - PMC
Journal
Experimental and therapeutic medicine
Oridonin Attenuates Lipopolysaccharide-Induced ROS Accumulation and Inflammation in HK-2 Cells
Journal
Evidence-based Complementary and Alternative Medicine : Ecam
Species
Homo sapiens, Mus musculus
Electroacupuncture alleviates Parkinson disease and regulates the expression of brain-gut peptides
Mitochondrial dysfunction in follicles is associated with broodiness in Zhedong white goose
Journal
Animal reproduction science
Analysis of cyclooxygenase 2, programmed cell death ligand 1, and arginase 1 expression in human pituitary adenoma
Journal
World neurosurgery
Biochanin A in murine Schistosoma mansoni infection: effects on inflammation, oxidative stress and fibrosis
Journal
Journal of helminthology
Lead suppresses perlecan expression via EGFR-ERK1/2-COX-2-PGI2 pathway in cultured bovine vascular endothelial cells
Journal
The Journal of toxicological sciences
Scutellarin Loaded on Ultradeformable Nanoliposome Scutellarin EDTMP (S-UNL-E) Promotes Osteogenesis in Osteoporotic Rats - PMC
Journal
Stem cells international