miR-301a promotes lung tumorigenesis by suppressing Runx3.
Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo: Role of DNA methyltransferase 1
Oroxylin A suppresses ACTN1 expression to inactivate cancer-associated fibroblasts and restrain breast cancer metastasis
Use of wogonin as a cooperative drug with praziquantel to better combat schistosomiasis
Journal
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Species
Mus musculus,Schistosoma mansoni
Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF1/SLC7A11 pathway
Journal
Cell proliferation
Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGFβ signaling
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients
Journal
Stem Cell Res Ther
Microvesicles from human adipose stem cells promote wound healing by optimizing cellular functions via AKT and ERK signaling pathways.
Journal
Stem cell research & therapy
Engineering alginate/carboxymethylcellulose scaffolds to establish liver cancer spheroids: Evaluation of molecular variances between 2D and 3D models
Journal
International journal of biological macromolecules
Biochanin A Ameliorates Nephropathy in High-Fat Diet/Streptozotocin-Induced Diabetic Rats: Effects on NF-kB/NLRP3 Axis, Pyroptosis, and Fibrosis - PMC
Journal
Antioxidants (Basel, Switzerland)
Repeated Administration of Cisplatin Transforms Kidney Fibroblasts through G2/M Arrest and Cellular Senescence - PMC
ADAM17: A novel treatment target for aneurysms
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
LncRNA GAS5 exacerbates renal tubular epithelial fibrosis by acting as a competing endogenous RNA of miR-96-5p
Journal
Biomedicine & Pharmacotherapy
Species
Homo sapiens, Mus musculus
Luteolin suppresses epithelial-mesenchymal transition and migration of triple-negative breast cancer cells by inhibiting YAP/TAZ activity
Journal
biomed pharmacother
Long-term explant culture: an improved method for consistently harvesting homogeneous populations of keloid fibroblasts
Biochanin A alleviates unilateral ureteral obstruction-induced renal interstitial fibrosis and inflammation by inhibiting the TGF-1/Smad2/3 and NF-kB/NLRP3 signaling axis in mice
Trigonelline mitigates bleomycin-induced pulmonary inflammation and fibrosis: Insight into NLRP3 inflammasome and SPHK1/S1P/Hippo signaling modulation
Oroxylin A reversed Fibronectin-induced glioma insensitivity to Temozolomide by suppressing IP3R1/AKT/-catenin pathway
Species
Homo sapiens, Mus musculus
Resveratrol exerts dose-dependent anti-fibrotic or pro-fibrotic effects in kidneys: A potential risk to individuals with impaired kidney function.
Species
Homo sapiens, Mus musculus
Tetraspanin 7 promotes osteosarcoma cell invasion and metastasis by inducing EMT and activating the FAK-Src-Ras-ERK1/2 signaling pathway
Journal
Cancer cell international
The Ameliorative Role of Lico A on Aflatoxin B1-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway
Journal
Journal of agricultural and food chemistry
Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1
Glycyrrhizic acid improves tacrolimusinduced renal injury by regulating autophagy
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Species
Homo sapiens, Mus musculus
Trigonelline hydrochloride attenuates silica-induced pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation - PMC
Journal
Respiratory research
Tspan9 Induces EMT and Promotes Osteosarcoma Metastasis via Activating FAK-Ras-ERK1/2 Pathway
Journal
Frontiers in oncology
Inactivation of ERK1/2 in cancer-associated hepatic stellate cells suppresses cancer-stromal interaction by regulating extracellular matrix in fibrosis - PMC
Journal
American journal of cancer research
Boswellianols A-I, Structurally Diverse Diterpenoids from the Oleo-Gum Resin of Boswellia carterii and Their TGF- Inhibition Activity - PMC
Journal
Plants (Basel, Switzerland)
High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway
Journal
Toxicology and applied pharmacology
Ultrasound-Guided Transplantation of Mesenchymal Stem Cells Improves Adriamycin Nephropathy in Rats through the RIPK3/MLKL and TLR-4/NF-κB signaling
Dysregulated lipid metabolism is associated with kidney allograft fibrosis - PMC
Journal
Lipids in health and disease
Species
Homo sapiens,Rattus norvegicus
Silencing of adipocyte enhancer-binding protein 1 (AEBP1) alleviates renal fibrosis in vivo and in vitro via inhibition of the -catenin signaling pathway
Species
Mus musculus,Homo sapiens
Silencing of RSPO1 mitigates obesity-related renal fibrosis in mice by deactivating Wnt/-catenin pathway
FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells - PMC
Journal
Journal of translational internal medicine
O-GlcNAcylation regulates HIF-1 and induces mesothelial-mesenchymal transition and fibrosis of human peritoneal mesothelial cells - PMC
EMT-related protein expression in polyploid giant cancer cells and their daughter cells with different passages after triptolide treatment.
Journal
Medical oncology (Northwood, London, England)
SiO2 dust induces inflammation and pulmonary fibrosis in rat lungs through activation of ASMase/Ceramide pathway
Journal
Journal of applied toxicology : JAT
GOLPH3 silencing inhibits adhesion of glioma U251 cells by regulating ITGB1 degradation under serum starvation
Journal
Biochem Biophys Res Commun
Chlorogenic acid alleviates renal fibrosis by reducing lipid accumulation in diabetic kidney disease through suppressing the Notch1 and Stat3 signaling pathway - PMC
Species
Homo sapiens,Mus musculus
Hirudo Lyophilized Powder Ameliorates Renal Injury in Diabetic Rats by Suppressing Oxidative Stress and Inflammation
Journal
Evid Based Complement Alternat Med
Dysregulated RUNX1 Predicts Poor Prognosis by Mediating Epithelialmesenchymal Transition in Cervical Cancer
Journal
Current medical science
Feline mammary carcinoma-derived extracellular vesicle promotes liver metastasis via sphingosine kinase-1-mediated premetastatic niche formation - PMC
Journal
Laboratory animal research
Species
Homo sapiens,Mus musculus
hUMSCs Restore Uterine Function by Inhibiting Endometrial Fibrosis via Regulation of the MMP-9/TIMP-1 Ratio in CDDP-Induced Injury Rats - PMC
Journal
Stem cells international