Biochanin A Ameliorates Nephropathy in High-Fat Diet/Streptozotocin-Induced Diabetic Rats: Effects on NF-kB/NLRP3 Axis, Pyroptosis, and Fibrosis - PMC
Journal
Antioxidants (Basel, Switzerland)
Abrocitinib Attenuates Microglia-Mediated Neuroinflammation after Traumatic Brain Injury via Inhibiting the JAK1/STAT1/NF-κB Pathway - PMC
Tanshinone IIA protects intestinal epithelial cells from deoxynivalenol-induced pyroptosis
Journal
Ecotoxicology and environmental safety
HgCl2 exposure mediates pyroptosis of HD11 cells and promotes M1 polarization and the release of inflammatory factors through ROS/Nrf2/NLRP3
Journal
Ecotoxicology and environmental safety
Mitochondrial damage and activation of the cytosolic DNA sensor cGAS-STING pathway lead to cardiac pyroptosis and hypertrophy in diabetic cardiomyopathy mice
Journal
Cell death discovery
Pyroptosis is involved in the inhibitory effect of FL118 on growth and metastasis in colorectal cancer
Foot-and-Mouth Disease Virus Induces Porcine Gasdermin E-Mediated Pyroptosis through the Protease Activity of 3Cpro
Journal
Journal of virology
Latex Derived from Ficus carica L. Inhibited the Growth of NSCLC by Regulating the Caspase/Gasdermin/AKT Signaling Pathway
Multi-regulatory potency of USP1 on inflammasome components promotes pyroptosis in thyroid follicular cells and contributes to the progression of Hashimoto's thyroiditis - PMC
Journal
Molecular medicine (Cambridge, Mass.)
Up-regulation of HSP90 in HDM-induced asthma causes pyroptosis of airway epithelial cells by activating the cGAS-STING-ER stress pathway
Journal
International immunopharmacology
Dapagliflozin prevents kidney podocytes pyroptosis via miR-155-5p/HO-1/NLRP3 axis modulation
Journal
International immunopharmacology
BRCC3 mediates inflammation and pyroptosis in cerebral ischemia/reperfusion injury by activating the NLRP6 inflammasome
Journal
CNS neuroscience & therapeutics
EEBR induces Caspase-1-dependent pyroptosis through the NF-B/NLRP3 signalling cascade in non-small cell lung cancer - PMC
Journal
Journal of cellular and molecular medicine
Mesenchymal stem cells ameliorate inflammation and pyroptosis in diabetic cardiomyopathy via the miRNA-223-3p/NLRP3 pathway - PMC
Journal
Diabetology & metabolic syndrome
Species
Mus musculus,Rattus norvegicus
Co-exposure of avermectin and imidacloprid induces DNA damage, pyroptosis, and immune dysfunction in epithelioma papulosum cyprini cells via ROS-mediated
Journal
Fish & shellfish immunology
Resveratrol improves emamectin benzoate-induced pyroptosis and inflammation of Ctenopharyngodon idellus hepatic cells by alleviating oxidative stress
Journal
Fish & shellfish immunology
Species
Ctenopharyngodon idellus
Semaglutide ameliorates pressure overload-induced cardiac hypertrophy by improving cardiac mitophagy to suppress the activation of NLRP3 inflammasome - PMC
Journal
Scientific reports
Oxymatrine Attenuates Ulcerative Colitis through Inhibiting Pyroptosis Mediated by the NLRP3 Inflammasome - PMC
Journal
Molecules (Basel, Switzerland)
Nitidine chloride induces caspase 3/GSDME-dependent pyroptosis by inhibting PI3K/Akt pathway in lung cancer - PMC
DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis
Journal
Neurochemical research
Exogenous Spermidine Alleviates Diabetic Myocardial Fibrosis Via Suppressing Inflammation and Pyroptosis in db/db Mice - PMC
Journal
Balkan medical journal
Dicoumarol attenuates NLRP3 inflammasome activation to inhibit inflammation and fibrosis in knee osteoarthritis - PMC
Journal
Molecular medicine reports
AIM2 inflammasome regulated by the IFN-/JAK2/STAT1 pathway promotes activation and pyroptosis of monocytes in Coronary Artery Disease - PMC
Journal
Immunity, inflammation and disease
Identification of an LDLR variant in a Chinese familial hypercholesterolemia and its relation to ROS/NLRP3-Mediated pyroptosis in hepatic cells - PMC
Journal
Journal of geriatric cardiology : JGC
Identification of an LDLR variant in a Chinese familial hypercholesterolemia and its relation to ROS/NLRP3-Mediated pyroptosis in hepatic cells - PMC
Journal
Journal of geriatric cardiology : JGC
Bone marrow mesenchymal stem cell‐derived exosomes miR‐202‐5p inhibited pyroptosis to alleviate lung ischemic‐reperfusion injury by targeting CMPK2
Journal
The Kaohsiung journal of medical sciences
Exploring the Potential Role of Dexmedetomidine in Reducing Postoperative Cognitive Dysfunction in Elderly Hip Fracture Patients - PMC
Journal
Actas espanolas de psiquiatria
ALKBH4 impedes 5-FU Sensitivity through suppressing GSDME induced pyroptosis in gastric cancer - PMC
Journal
Cell death & disease
SLC25A3 negatively regulates NLRP3 inflammasome activation by restricting the function of NLRP3 - PMC
Journal
The Journal of biological chemistry
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer