ATG14 targets lipid droplets and acts as an autophagic receptor for syntaxin18-regulated lipid droplet turnover - PMC
Journal
Nature communications
Hepatitis B Virus Induces Autophagy to Promote its Replication by the Axis of miR1923pXIAP via NFB Signaling
Journal
Hepatology (Baltimore, Md.)
Autophagy-mediated compartmental cytoplasmic deletion is essential for tobacco pollen germination and male fertility
Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy
Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production
Melatonin Mitigates Atrazine-Induced Renal Tubular Epithelial Cell Senescence by Promoting Parkin-Mediated Mitophagy - PMC
Journal
Research (Washington, D.C.)
Doxorubicin-polyglycerol-nanodiamond composites stimulate glioblastoma cell immunogenicity through activation of autophagy.
Journal
Acta biomaterialia
Plant UVRAG interacts with ATG14 to regulate autophagosome maturation and geminivirus infection
Journal
The New phytologist
Lycopene mitigates DEHP-induced hepatic mitochondrial quality control disorder via regulating SIRT1/PINK1/mitophagy axis and mitochondrial unfolded protein response
MiR-127-3p targeting CISD1 regulates autophagy in hypoxic-ischemic cortex
Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson's disease.
Journal
Cell death & disease
Liposomal UHRF1 siRNA shows lung fibrosis treatment potential by regulating fibroblast activation
Battery wastewater induces nephrotoxicity via disordering the mitochondrial dynamics
Upregulation of thioredoxin contributes to inhibiting diabetic hearing impairment
Journal
Diabetes research and clinical practice
Oyster (Crassostrea gigas) ferritin relieves lead-induced liver oxidative damage via regulating the mitophagy
Journal
International journal of biological macromolecules
Beclin1 controls caspase-4 inflammsome activation and pyroptosis in mouse myocardial reperfusion-induced microvascular injury
Journal
Cell Commun Signal
Calenduloside E protects against myocardial ischemia-reperfusion injury induced calcium overload by enhancing autophagy and inhibiting L-type Ca2+ channels …
Journal
Biomed Pharmacother
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway - PMC
Journal
Respiratory research
Long-term exposure to the fluoride blocks the development of chondrocytes in the ducks: The molecular mechanism of fluoride regulating autophagy and apoptosis
Journal
Ecotoxicol Environ Saf
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1 - PMC
Journal
Cell death discovery
Buformin alleviates sepsis-induced acute lung injury via inhibiting NLRP3-mediated pyroptosis through an AMPK-dependent pathway
Journal
Clinical science (London, England : 1979)
FK866 attenuates sepsis-induced acute lung injury through c-jun-N-terminal kinase (JNK)-dependent autophagy
Astragaloside IV-targeting miRNA-1 attenuates lipopolysaccharide-induced cardiac dysfunction in rats through inhibition of apoptosis and autophagy
Anti-inflammatory activity of carvacrol protects the heart from lipopolysaccharide-induced cardiac dysfunction by inhibiting pyroptosis via NLRP3/Caspase1/Gasdermin …
Adipose-derived stem cells reduce liver oxidative stress and autophagy induced by ischemia-reperfusion and hepatectomy injury in swine.
ATG16L2 inhibits NLRP3 inflammasome activation through promoting ATG5-12-16L1 complex assembly and autophagy
Journal
European journal of immunology
nNovel insights into antidepressant mechanism of Kai Xin San formula: inhibiting NLRP3 inflammasome activation by promoting autophagy
Dietary Phosphorus Reduced Hepatic Lipid Deposition by Activating Ampk Pathway and Beclin1 Phosphorylation Levels to Activate Lipophagy in Tilapia Oreochromis niloticus
Journal
Frontiers in nutrition
Autophagy benefits the replication of influenza A virus in vitro.
Journal
Journal of virology
Bone marrow mesenchymal stem cells-derived conditioned medium protects cardiomyocytes from hypoxia/reoxygenation-induced injury through Notch2/mTOR/autophagy signaling.
Journal
Journal of cellular physiology
Baicalin reverses radioresistance in nasopharyngeal carcinoma by downregulating autophagy
Journal
Cancer Cell International
Calcium/calmodulin dependent protein kinase IV in trophoblast cells under insulin resistance: functional and metabolomic analyses - PMC
Journal
Molecular medicine (Cambridge, Mass.)
Galangin inhibits neointima formation induced by vascular injury via regulating the PI3K/AKT/mTOR pathway
Chlorogenic Acid Alleviates Thiram-Induced Tibial Dyschondroplasia by Modulating Caspases, BECN1 Expression and ECM Degradation.
Journal
International Journal of Molecular Sciences
Dietary Leucine Improves Fish Intestinal Barrier Function by Increasing Humoral Immunity, Antioxidant Capacity, and Tight Junction - PMC
Journal
International journal of molecular sciences
Species
Horabagrus nigricollaris
Leucine mediates cognitive dysfunction in early life stress-induced mental disorders by activating autophagy - PMC
Journal
Frontiers in cellular neuroscience
Betaine attenuates age-related suppression in autophagy via Mettl21c/p97/VCP axis to delay muscle loss
Journal
The Journal of nutritional biochemistry
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Monocyte-mediated chemotherapy drug delivery in glioblastoma
Journal
Nanomedicine (London, England)
Autophagy Is a Defense Mechanism Inhibiting Invasion and Inflammation During High-Virulent Haemophilus parasuis Infection in PK-15 Cells.
Journal
Frontiers in Cellular and Infection Microbiology
RRM2 Alleviates Doxorubicin-Induced Cardiotoxicity through the AKT/mTOR Signaling Pathway
Identification and validation of ferroptosis key genes in bone mesenchymal stromal cells of primary osteoporosis based on bioinformatics analysis - PMC
Journal
Frontiers in endocrinology
Ag120-Mediated Inhibition of ASCT2-Dependent Glutamine Transport has an Anti-Tumor Effect on Colorectal Cancer Cells
Journal
Frontiers in pharmacology
EGCG protects the mouse brain against cerebral ischemia/reperfusion injury by suppressing autophagy via the AKT/AMPK/mTOR phosphorylation pathway - PMC
Journal
Frontiers in pharmacology
Electroacupuncture ameliorates AOM/DSS-induced mice colorectal cancer by inhibiting inflammation and promoting autophagy via the SIRT1/miR-215/Atg14 axis - PMC
Electroacupuncture ameliorates AOM/DSS-induced mice colorectal cancer by inhibiting inflammation and promoting autophagy via the SIRT1/miR-215/Atg14 axis - PMC
Species
Homo sapiens,Mus musculus
TGF-β1 Promotes Autophagy and Inhibits Apoptosis in Breast Cancer by Targeting TP63
Journal
Frontiers in oncology
Syndecan 4 contributes to osteoclast differentiation induced by RANKL through enhancing autophagy
Journal
International immunopharmacology
Genipin protects rats against lipopolysaccharide-induced acute lung injury by reinforcing autophagy.
Journal
International immunopharmacology
Ameliorative effects of eosinophil deficiency on immune response, endoplasmic reticulum stress, apoptosis, and autophagy in fungus-induced allergic lung inflammation
cGAS-STING pathway aggravates early cerebral ischemia-reperfusion injury in mice by activating NCOA4-mediated ferritinophagy
Journal
Experimental neurology
Berberine mitigates IL-21/IL-21R mediated autophagic influx in fibroblast-like synoviocytes and regulates Th17/Treg imbalance in rheumatoid arthritis.
Journal
Apoptosis : an international journal on programmed cell death
Autophagy induced by Vip3Aa has a pro-survival role in Spodoptera frugiperda Sf9 cells
Species
Spodoptera frugiperda
A Self-Assembly ICG Nanoparticle Potentiating Targeted Photothermal and Photodynamic Therapy in NSCLC
Journal
ACS biomaterials science & engineering
Redd1 protects against post‑infarction cardiac dysfunction by targeting apoptosis and autophagy
Journal
International Journal of Molecular Medicine
Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR-29b-3p - PMC
Journal
International journal of molecular medicine
UBE2T is upregulated, predicts poor prognosis, and promotes cell proliferation and invasion by promoting epithelial-mesenchymal transition via inhibiting autophagy in an AKT/mTOR dependent manner in ovarian cancer
Journal
Cell cycle (Georgetown, Tex.)
The role of mitochondrial dynamics imbalance in hexavalent chromium-induced apoptosis and autophagy in rat testis
Journal
Chemico-biological interactions
Orphan nuclear receptor NUR77 relieves insulin resistance in HTR-8/SVneo trophoblast cells through activation of autophagy and insulin signaling
Journal
Journal of physiology and biochemistry
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway
Journal
Biochim Biophys Acta Mol Cell Res
Exogenous H2S alleviates senescence of glomerular mesangial cells through up-regulating mitophagy by activation of AMPK-ULK1-PINK1-parkin pathway in mice
Journal
Biochimica et biophysica acta. Molecular cell research
Autophagy induces apoptosis and death of T lymphocytes in the spleen of pigs infected with CSFV
Journal
Scientific reports
TCS2 Increases Olaquindox-Induced Apoptosis by Upregulation of ROS Production and Downregulation of Autophagy in HEK293 Cells.
Beclin-1 overexpression regulates NLRP3 activation by promoting TNFAIP3 in microvascular injury following myocardial reperfusion
Computational and Experimental Approaches Exploring the Role of Hesperetin in Improving Autophagy in Rat Diabetic Retinopathy - PMC
Butyrate induces STAT3/HIF-1/IL-22 signaling via GPCR and HDAC3 inhibition to activate autophagy in head kidney macrophages from turbot (Scophthalmus
Journal
Fish & shellfish immunology
Choline Inhibits Ischemia-Reperfusion-Induced Cardiomyocyte Autophagy in Rat Myocardium by Activating Akt/mTOR Signaling
Journal
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
Identification of Key Genes and Potential Mechanisms Based on the Autophagy Regulatory Network in Osteoclasts Using a Murine Osteoarthritis Model
Journal
Journal of inflammation research
Curcumin-Alleviated Osteoarthritic Progression in Rats Fed a High-Fat Diet by Inhibiting Apoptosis and Activating Autophagy via Modulation of MicroRNA-34a
Inhibition of miRNA-1-Mediated Inflammation and Autophagy by Astragaloside IV Improves Lipopolysaccharide-Induced Cardiac Dysfunction in Rats
Journal
Journal of inflammation research
Melatonin ameliorates nickel induced autophagy in mouse brain: Diminution of oxidative stress
Autophagy inhibition promotes phagocytosis of macrophage and protects mice from methicillin‐resistant staphylococcus aureus pneumonia
Journal
Journal of Cellular Biochemistry
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways
Journal
Psychopharmacology
Nucleotide-binding oligomerization domain protein 1 enhances oxygen-glucose deprivation and reperfusion injury in cortical neurons via activation of endoplasmic reticulum stress-mediated autophagy
Clostridium butyricum Alleviates Gut Microbiota AlterationInduced Bone Loss after Bariatric Surgery by Promoting Bone Autophagy
Journal
The Journal of pharmacology and experimental therapeutics
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m6A modification
CF101 alleviates OA progression and inhibits the inflammatory process via the AMP/ATP/AMPK/mTOR axis
Long Noncoding RNA ADAMTS9-AS2 Inhibits the Proliferation, Migration, and Invasion in Bladder Tumor Cells
Ginsenoside Rd Promotes Cardiac Repair After Myocardial Infarction by Modulating Monocytes/Macrophages Subsets Conversion - PMC
Journal
Drug design, development and therapy
Hydrogen sulfide attenuates ferroptosis and stimulates autophagy by blocking mTOR signaling in sepsis-induced acute lung injury
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells - PMC
The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia
Journal
Anal Cell Pathol (Amst)
Curcumin attenuates diphenyl phosphateinduced apoptosis in GC2spd (ts) cells through activated autophagy via the Nrf2/P53 pathway
Journal
Environmental toxicology
MiR-34a-5p promotes autophagy and apoptosis of ovarian granulosa cells via the Hippo-YAP signaling pathway by targeting LEF1 in chicken - PMC
Selenium regulates Nrf2 signaling to prevent hepatotoxicity induced by hexavalent chromium in broilers - PMC
Astragalus polysaccharide alleviates transport stress-induced heart injury in newly hatched chicks via ERS-UPR-autophagy dependent pathway - PMC
FoxG1 as a Potential Therapeutic Target for Alzheimers Disease: Modulating NLRP3 Inflammasome via AMPK/mTOR Autophagy Pathway - PMC
Journal
Cellular and molecular neurobiology
Long non-coding RNA ADAMTS9-AS1 exacerbates cell proliferation, migration, and invasion via triggering of the PI3K/AKT/mTOR pathway in hepatocellular …
Long non-coding RNA ADAMTS9-AS1 exacerbates cell proliferation, migration, and invasion via triggering of the PI3K/AKT/mTOR pathway in hepatocellular …
TLR4 inhibited autophagy by modulating PI3K/AKT/mTOR signaling pathway in Gastric cancer cell lines
Running Improves Muscle Mass by Activating Autophagic Flux and Inhibiting Ubiquitination Degradation in Mdx Mice
The potential benefits of PGC-1 in treating Alzheimer's disease are dependent on the integrity of the LLKYL L3 motif: Effect of regulating mitochondrial axonal
Journal
Experimental gerontology
Osthole protects H9c2 cardiomyocytes against trastuzumab-induced damage by enhancing autophagy through the p38MAPK/mTOR signaling pathway
Journal
Toxicology in vitro : an international journal published in association with BIBRA
Tight Junction Protein 1 Suppresses Kidney Renal Clear Cell Carcinoma Cells Proliferation by Inducing Autophagy - PMC
Journal
International journal of medical sciences
MicroRNA?16?5p/BIMP1/NF?κB axis regulates autophagy to exert a tumor?suppressive effect on bladder cancer
Sodium butyrate induces autophagic apoptosis of nasopharyngeal carcinoma cells by inhibiting AKT/mTOR signaling.
Journal
Biochemical and biophysical research communications
Angiotensin-(1-7) suppresses airway inflammation and airway remodeling via inhibiting ATG5 in allergic asthma - PMC
Journal
BMC pulmonary medicine
Ischemia reperfusion myocardium injuries in type 2 diabetic rats: Effects of ketamine and insulin on LC3-II and mTOR expression - PMC
Journal
International journal of immunopathology and pharmacology
Vitamin D alleviates hypoxia/reoxygenation-induced injury of human trophoblast HTR-8 cells by activating autophagy
Autophagy is a defense mechanism controlling Streptococcus suis serotype 2 infection in murine microglia cells
Effects of Cobalt Chloride, a Hypoxia-Mimetic Agent, on Autophagy and Atrophy in Skeletal C2C12 Myotubes
Journal
Biomed Research International
Nicotinic Acid Riboside Regulates Nrf-2/P62-Related Oxidative Stress and Autophagy to Attenuate Doxorubicin-Induced Cardiomyocyte Injury
Journal
BioMed research international
GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal
Autophagy inhibition mediated by trillin promotes apoptosis in hepatocellular carcinoma cells via activation of mTOR/STAT3 signaling
Journal
Naunyn-Schmiedeberg's archives of pharmacology
Regulatory relationship between macrophage autophagy and PVL-positive methicillin-resistant Staphylococcus aureus
Lysosomal dysfunction disturbs porcine oocyte maturation and developmental capacity by disorganizing chromosome/cytoskeleton and activating autophagy/apoptosis.
Isoschaftoside Reverses Nonalcoholic Fatty Liver Disease via Activating Autophagy In Vivo and In Vitro - PMC
Journal
Evidence-based complementary and alternative medicine : eCAM
Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway
Journal
Evidence-based complementary and alternative medicine : eCAM
Bone marrow mesenchymal stem cell derived exosomal miR-455-5p protects against spinal cord ischemia reperfusion injury
Ginsenoside Rg3 protects heart against isoproterenol-induced myocardial infarction by activating AMPK mediated autophagy.
Journal
Cardiovascular Diagnosis and Therapy
Hinokitiol Inhibits the Viability of Oral Squamous Carcinoma Cells by Inducing Apoptosis and Autophagy
Journal
Anticancer research
Metabolomics Analysis Reveals Alterations in Cochlear Metabolic Profiling in Mice with Noise-Induced Hearing Loss
Journal
BioMed research international
Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival
Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival
Expression of Autophagy Markers Beclin1 and LC3B in Prostatic Carcinoma: An Immunohistochemical Case-Control Study
Journal
Iranian journal of pathology
Species
Homo sapiens,Rattus norvegicus
Parathyroid hormone-(1–34) ameliorated knee osteoarthritis in rats via autophagy
Journal
Journal of applied physiology (Bethesda, Md. : 1985)
Metabolic shift induced by ω-3 PUFAs and rapamycin lead to cancer cell death
Journal
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
p62/SQSTM1 protects against cisplatin-induced oxidative stress in kidneys by mediating the cross talk between autophagy and the Keap1-Nrf2 signalling pathway
Journal
Free radical research