Macrophage Inactivation
by Small Molecule Wedelolactone
via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury - PMC
Journal
ACS central science
Filamin C regulates skeletal muscle atrophy by stabilizing dishevelled-2 to inhibit autophagy and mitophagy
Journal
Molecular therapy. Nucleic acids
A novel kinase inhibitor, LZT-106, downregulates Mcl-1 and sensitizes colorectal cancer cells to BH3 mimetic ABT-199 by targeting CDK9 and GSK-3β signaling
Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1‐WNT2/HGF signaling pathway
Oroxylin A reversed Fibronectin-induced glioma insensitivity to Temozolomide by suppressing IP3R1/AKT/-catenin pathway
Species
Homo sapiens, Mus musculus
ANKRD1 activates the Wnt signaling pathway by modulating CAV3 expression and thus promotes BMSC osteogenic differentiation and bone formation in …
Journal
Biochimica et biophysica acta. Molecular basis of disease
Mucosal ribosomal stress-induced PRDM1 promotes chemoresistance via stemness regulation
N-glycosylated SGK196 suppresses the metastasis of basal-like breast cancer cells
Oleanolic acid, a small-molecule natural product, inhibits ECM degeneration in osteoarthritis by regulating the Hippo/YAP and Wnt/-catenin pathways
Catalpol Protects Against Pulmonary Fibrosis Through Inhibiting TGF-1/Smad3 and Wnt/-Catenin Signaling Pathways
Tirzepatide ameliorates spatial learning and memory impairment through modulation of aberrant insulin resistance and inflammation response in diabetic rats - PMC
Journal
Frontiers in pharmacology
Gypenoside IX restores Akt/GSK-3 pathway and alleviates Alzheimers disease-like neuropathology and cognitive deficits - PMC
Toosendanin suppresses oncogenic phenotypes of human gastric carcinoma SGC?7901 cells partly via miR?200a?mediated downregulation of β-catenin pathway
Journal
International Journal of Oncology
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3/Nrf2 signaling-mediated ferroptosis in vivo and in vitro
Journal
International immunopharmacology
Species
Homo sapiens,Rattus norvegicus
WSB1, as an E3 ligase, restrains myocardial ischemia-reperfusion injury by activating -catenin signaling via promoting GSK3 ubiquitination - PMC
Journal
Molecular medicine (Cambridge, Mass.)
Schisandrin A Alleviates Spatial Learning and Memory Impairment in Diabetic Rats by Inhibiting Inflammatory Response and Through Modulation of the PI3K/AKT
Journal
Molecular neurobiology
Isobavachalcone's Alleviation of Pyroptosis Contributes to Enhanced Apoptosis in Glioblastoma: Possible Involvement of NLRP3
Journal
Molecular neurobiology
Macropinocytic cups function as signal platforms for the mTORC2-AKT pathway to modulate LPS-induced cytokine expression in macrophages
Journal
Journal of leukocyte biology
MicroRNA-137 inhibits pituitary prolactinoma proliferation by targeting AKT2
Journal
Journal of endocrinological investigation
Inula japonica ameliorated bleomycin-induced pulmonary fibrosis via inhibiting soluble epoxide hydrolase
Journal
Bioorganic chemistry
The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the underlying signaling mechanisms in a rat model of diabetes mellitus
Journal
Scientific Reports
Ethanol Extract of Rosa laevigata Michx. Fruit Inhibits Inflammatory Responses through NF-B/MAPK Signaling Pathways via AMPK Activation in RAW 264.7 Macrophages - PMC
Journal
Molecules (Basel, Switzerland)
CCDC85C suppresses colorectal cancer cells proliferation and metastasis through activating GSK-3 and promoting -catenin degradation
Journal
Cellular signalling
Selenium supplementation protects against oxidative stress-induced cardiomyocyte cell cycle arrest through activation of PI3K/AKT
Journal
Metallomics : integrated biometal science
Syringaldehyde Exhibits Antibacterial and Antioxidant Activities against Mycobacterium marinum Infection - PMC
Bai-He-Gu-Jin-Tang formula suppresses lung cancer via AKT/GSK3β/β-catenin and induces autophagy via the AMPK/mTORC1/ULK1 signaling pathway
Anwulignan Ameliorates the Intestinal Ischemia/Reperfusion
Journal
The Journal of pharmacology and experimental therapeutics
Nucleoporin 93, a new substrate of the E3 ubiquitin protein ligase HECTD1, promotes esophageal squamous cell carcinoma progression
TSPAN31 suppresses cell proliferation in human cervical cancer through down‐regulation of its antisense pairing with CDK4
Journal
Cell biochemistry and function
The systematic regulation of oyster CgIL17-1 and CgIL17-5 in response to air exposure
Journal
Developmental and comparative immunology
Schisandra chinensis acidic polysaccharide partialy reverses acetaminophen-induced liver injury in mice
Journal
Journal of pharmacological sciences
Liraglutide and Insulin Have Contrary Effects on Adipogenesis of Human Adipose-Derived Stem Cells via Wnt Pathway
Journal
Diabetes Metab Syndr Obes
Effect of (m)RVD-hemopressin against Aβ1-42-induced apoptosis and inhibition of neurite outgrowth in SH-SY5Y cells
ZnSO4 Protects against premature ovarian failure through PI3K/AKT/GSK3β signaling pathway
Role of Chrysophanol in Epithelial-Mesenchymal Transition in Oral Cancer Cell Lines via a Wnt-3-Dependent Pathway
Journal
Evid Based Complement Alternat Med
HOXB5 promotes proliferation, migration, and invasion of pancreatic cancer cell through the activation of the GSK3β/β-catenin pathway
Urantide alleviates atherosclerosis-related liver and kidney injury via the Wnt/-catenin signaling pathway in ApoE (/) mice
The Polysaccharides from the Aerial Parts of Bupleurum chinens e DC Attenuate Epilepsy-Like Behavior through Oxidative Stress Signaling Pathways
Journal
Oxidative medicine and cellular longevity