Original research: Colorectal cancer-specific IFN delivery overcomes dysfunctional dsRNA-mediated type I interferon signaling to increase the abscopal effect of radiotherapy - PMC
Journal
Journal for immunotherapy of cancer
TAGAP expression influences CD4+ T cell differentiation, immune infiltration, and cytotoxicity in LUAD through the STAT pathway: implications for immunotherapy - PMC
Journal
Frontiers in immunology
Porcine deltacoronavirus NS7a antagonizes JAK/STAT pathway by inhibiting the interferon-stimulated gene factor 3 (ISGF3) formation
Journal
International journal of biological macromolecules
Abrocitinib Attenuates Microglia-Mediated Neuroinflammation after Traumatic Brain Injury via Inhibiting the JAK1/STAT1/NF-κB Pathway - PMC
GETV nsP2 plays a critical role in the interferon antagonism and viral pathogenesis - PMC
Journal
Cell communication and signaling : CCS
Species
Homo sapiens, Mus musculus
The NP protein of Newcastle disease virus dictates its oncolytic activity by regulating viral mRNA translation efficiency - PMC
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Npro of classical swine fever virus enhances HMGB1 acetylation and its degradation by lysosomes to evade from HMGB1-mediated antiviral immunity - PMC
Angiotensin converting enzyme 2 does not facilitate porcine epidemic diarrhea virus entry into porcine intestinal epithelial cells and inhibits it-induced inflammatory injury by promoting STAT1 phosphorylation - PMC
Exploring the potential molecular mechanism of trastuzumab-induced cardiotoxicity based on RNA sequencing and bioinformatics analysis
Journal
Biochemical pharmacology
Harmine Alleviated Sepsis-Induced Cardiac Dysfunction by Modulating Macrophage Polarization via the STAT/MAPK/NF-B Pathway.
Journal
Frontiers in cell and developmental biology
Metformin suppresses gastric cancer progression by disrupting the STAT1-PRMT1 axis
Journal
Biochemical pharmacology
Metformin suppresses gastric cancer progression by disrupting the STAT1-PRMT1 axis
Journal
Biochemical pharmacology
Rosmarinic acid alleviates inflammation, apoptosis, and oxidative stress through regulating miR-155-5p in a mice model of Parkinson's disease
Journal
ACS chemical neuroscience
Upadacitinib inhibits corneal inflammation and neovascularization by suppressing M1 macrophage infiltration in the corneal alkali burn model
Journal
International immunopharmacology
Polygalaxanthone III, an Active Ingredient in Polygala japonica Houtt., Repaired Malassezia-Stimulated Skin Injury via STAT3 Phosphorylated Activation - PMC
Journal
Molecules (Basel, Switzerland)
NMI Functions as Immuno-regulatory Molecule in Sepsis by Regulating Multiple Signaling Pathways
Immunoreactive Microenvironment Modulator GBP5 Suppresses Ovarian Cancer Progression by Inducing Canonical Pyroptosis - PMC
Extracellular vesicles derived from HuMSCs alleviate daunorubicin-induced cardiac microvascular injury via miR-186-5p/PARP9/STAT1 signal pathway - PMC
Journal
Regenerative therapy
Polygalaxanthone III downregulates inflammation in the lipopolysaccharide-stimulated RAW264. 7 macrophages: A quantibody array analysis
Journal
Journal of pharmacological sciences
Topical Administration of 0.3% Tofacitinib Suppresses M1 Macrophage Polarization and Allograft Corneal Rejection by Blocking STAT1 Activation in the Rat Cornea
Journal
Translational vision science & technology
Species
Homo sapiens,Rattus norvegicus
Parasympathetic-macrophages-ductal epithelial cells axis promotes female rat submandibular gland regeneration after excretory duct ligation/deligation
Journal
Archives of oral biology
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
Strategy To Assess Zoonotic Potential Reveals Low Risk Posed by SARS-Related Coronaviruses from Bat and Pangolin
MicroRNA-379-5p regulates free cholesterol accumulation and relieves diet induced-liver damage in db/db mice via STAT1/HMGCS1 axis - PMC
Journal
Molecular biomedicine
Intrinsic features of Zika Virus non-structural proteins NS2A and NS4A in the regulation of viral replication
Journal
PLoS neglected tropical diseases