产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
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* This package insert must be read in its entirety before using this product.
Human CFD multiplex assay
| Recommended Concentration | Sample | |
|---|---|---|
| Multiplex Capture | 3-20ug/mL | Rabbit anti-Human CFD mAb(Cat. No.RMK0314) |
| Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human CFD mAb(Cat. No.RMK0315) |
| Standard | 6.86-5000pg/mL | Recombinant Human CFD Protein |
This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
