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Recombinant Human DNMT3A Protein (RP01971LQ)

货号: RP01971LQ
促销价:   ¥1800
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详细信息

种属
表达宿主
HEK293 cells
标签
储存
Store at -70°C. This product is stable at ≤ -70°C for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.未开盖的干粉蛋白在 -20°C至-80°C可保存12个月;
复溶之后,蛋白溶液在-20°C及以下可保存3个月,在2-8℃可保存1周。

蛋白复溶计算器

请在蛋白复溶计算器中输入蛋白总质量和所需终浓度,快速计算您需要添加溶液的体积吧!
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折叠内容

背景信息

DNMT3A, as de novo DNA methyltransferase, is essential for regulating gene expression through cellular development and differentiation.IT Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development .It modifies DNA in a non-processive manner and also methylates non-CpG sites . The functions of DNMT3A rely on its oligomeric states and allosteric regulations between its catalytic domain and binding partners. DNMT3A variants are present in elderly healthy individuals and patients with AML in complete remission, which suggests that DNMT3A mutations may contribute to pre-leukemic clonal hematopoiesis.

基因ID
Swiss Prot
别名
DNMT3A;DNA (cytosine-5)-methyltransferase 3A; Dnmt3a; Cysteine methyltransferase DNMT3A; DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA; M.HsaIIIA
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