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Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer

发表于《Journal of medicinal chemistry》2023Pubmed ID:37452764IF: 8.03
引用产品:C11 BODIPY 581/591 脂质过氧化荧光探针 (RM02821)
Species:Homo sapiens
Application:Lipid peroxidation determination

Identification of Lipocalin 2 as a Ferroptosis-Related Key Gene Associated with Hypoxic-Ischemic Brain Damage via STAT3/NF-κB Signaling Pathway - PMC

发表于《Antioxidants (Basel, Switzerland)》2023Pubmed ID:36671050IF: 7.67
引用产品:C11 BODIPY 581/591 脂质过氧化荧光探针 (RM02821)
Species:Homo sapiens
Application:Lipid Peroxidation
引用产品:STAT3 Rabbit pAb (A1192)
基因ID:6774
Species:Homo sapiens
Application:WB
引用产品:Lipocalin-2/NGAL Rabbit pAb (A2092)
基因ID:3934
Species:Homo sapiens
Application:WB
引用产品:ACSL4 Rabbit pAb (A6826)
基因ID:2182
Species:Homo sapiens
Application:WB
引用产品:Phospho-STAT3-Y705 Rabbit pAb (AP0070)
基因ID:6774
Species:Homo sapiens
Application:WB

NEK8 regulates colorectal cancer progression via phosphorylating MYC - PMC

发表于《Cell communication and signaling : CCS》2023Pubmed ID:37596667IF: 7.52
引用产品:GAPDH Rabbit mAb (A19056)
基因ID:2597
Species:Homo sapiens
Application:WB
引用产品:CCK-8试剂盒 (RM02823)
Species:Homo sapiens
Application:Cell Proliferation/Cytotoxicity Assay
引用产品:c-Myc Rabbit pAb (A1309)
基因ID:4609
Species:Homo sapiens
Application:WB
引用产品:Genious 2X SYBR Green Fast qPCR Mix (RK21204)
Species:Homo sapiens
Application:qPCR
引用产品:ABScript II cDNA First-Strand Synthesis Kit (RK20400)
Species:Homo sapiens
Application:RT-qPCR

Dual PI3K/mTOR inhibitor PF-04979064 regulates tumor growth in gastric cancer and enhances drug sensitivity of gastric cancer cells to 5-FU

发表于《Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie》2023Pubmed ID:38159377IF: 7.41
引用产品:[KO Validated] Cyclin D1 Rabbit mAb (A19038)
基因ID:595
Species:Homo sapiens
Application:WB
引用产品:AKT1 Rabbit pAb (A11016)
基因ID:207
Species:Homo sapiens
Application:WB
引用产品:[KO Validated] Bax Rabbit pAb (A0207)
基因ID:581
Species:Homo sapiens
Application:WB
引用产品:Cyclin A1 Rabbit pAb (A5631)
基因ID:8900
Species:Homo sapiens
Application:WB
引用产品:PCNA Rabbit pAb (A0264)
基因ID:5111
Species:Homo sapiens
Application:WB
引用产品:MMP9 Rabbit pAb (A0289)
基因ID:4318
Species:Homo sapiens
Application:WB
引用产品:S6 Ribosomal Protein (RPS6) Rabbit mAb (A11874)
基因ID:6194
Species:Homo sapiens
Application:WB
引用产品:CCK-8试剂盒 (RM02823)
Species:Homo sapiens
引用产品:Bcl-2 Rabbit pAb (A0208)
基因ID:596
Species:Homo sapiens
Application:WB

Trigonelline inhibits tubular epithelial-mesenchymal transformation in diabetic kidney disease via targeting Smad7

发表于《Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie》2023Pubmed ID:37864898IF: 7.41
引用产品:CCK-8试剂盒 (RM02823)
Species:Homo sapiens
Application:cell viability assay
引用产品:ABflo® 594-conjugated Goat anti-Rabbit IgG (H+L) (AS039)
Species:Homo sapiens
Application:IF
引用产品:ABflo® 488-conjugated Goat anti-Rabbit IgG (H+L) (AS053)
Species:Homo sapiens
Application:IF

Exposure to Di-(2-Ethylhexyl) phthalate drives ovarian dysfunction by inducing granulosa cell pyroptosis via the SLC39A5/NF-κB/NLRP3 axis

发表于《Ecotoxicology and environmental safety》2023Pubmed ID:36774801IF: 7.12
引用产品:HighGene transfection reagent (RM09014)
Species:Homo sapiens
Application:transfection

RPLP2 activates TLR4 in an autocrine manner and promotes HIF-1-induced metabolic reprogramming in hepatocellular carcinoma - PMC

发表于《Cell death discovery》2023Pubmed ID:38052785IF: 7.1
引用产品:Mouse Control IgG (AC011)
Species:Homo sapiens
Application:Co-IP
引用产品:HIF1α Rabbit pAb (A7684)
基因ID:3091
Species:Homo sapiens
Application:WB
引用产品:HRP-conjugated Goat anti-Mouse IgG Heavy Chain (AS064)
Species:Homo sapiens
Application:WB
引用产品:HRP-conjugated Goat anti-Rabbit IgG Heavy Chain (AS063)
Species:Homo sapiens
Application:WB
引用产品:β-Actin Rabbit mAb (High Dilution) (AC026)
基因ID:60
Species:Homo sapiens
Application:WB
引用产品:ECL Basic Kit {ECL化学发光底物(普通型)} (RM00020)
Species:Homo sapiens
Application:WB
引用产品:Histone H3 Rabbit pAb (A2348)
基因ID:8290/8350
Species:Homo sapiens
Application:WB

Design, synthesis and evaluation of novel UDCA-aminopyrimidine hybrids as ATX inhibitors for the treatment of hepatic and pulmonary fibrosis

发表于《European journal of medicinal chemistry》2023Pubmed ID:38091892IF: 7.08
引用产品:HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014)
Species:Homo sapiens
Application:WB
引用产品:Phospho-Smad3-S423/S425 Rabbit mAb (AP0727)
基因ID:4088
Species:Homo sapiens
Application:WB
引用产品:β-Actin Rabbit mAb (High Dilution) (AC026)
基因ID:60
Species:Homo sapiens
Application:WB
引用产品:Phospho-Smad2-S245/S250/S255 Rabbit mAb (AP1338)
基因ID:4087
Species:Homo sapiens
Application:WB
引用产品:α-Smooth Muscle Actin (ACTA2) Rabbit mAb (A17910)
基因ID:59
Species:Homo sapiens
Application:WB
引用产品:ECL Enhanced Plus Kit {ECL化学发光底物Plus(增强型)} (RM00021P)
Species:Homo sapiens
Application:WB
引用产品:Smad3 Rabbit pAb (A16913)
基因ID:4088
Species:Homo sapiens
Application:WB
引用产品:Collagen I/COL1A1 Rabbit pAb (A1352)
基因ID:1277
Species:Homo sapiens
Application:WB
引用产品:[KO Validated] Smad2 Rabbit pAb (A7699)
基因ID:4087
Species:Homo sapiens
Application:WB
引用产品:Fibronectin Rabbit pAb (A16678)
基因ID:2335
Species:Homo sapiens
Application:WB

Novel Platinum (IV) complexes intervene oxaliplatin resistance in colon cancer via inducing ferroptosis and apoptosis

发表于《European journal of medicinal chemistry》2023Pubmed ID:37995563IF: 6.7
引用产品:C11 BODIPY 581/591 脂质过氧化荧光探针 (RM02821)
Species:Homo sapiens
Application:Other

Integration with Transcriptomic and Metabolomic Analyses Reveals the In Vitro Cytotoxic Mechanisms of Chinese Poplar Propolis by Triggering the Glucose Metabolism in Human Hepatocellular Carcinoma Cells - PMC

发表于《Nutrients》2023Pubmed ID:37892405IF: 6.7
引用产品:蛋白酶抑制剂Cocktail (不含EDTA，100X DMSO储液) (RM02916)
Species:Homo sapiens
Application:WB

Apigenin ameliorates non-eosinophilic inflammation, dysregulated immune homeostasis and mitochondria-mediated airway epithelial cell apoptosis in chronic obese …

发表于《Phytomedicine : international journal of phytotherapy and phytopharmacology》2023Pubmed ID:36645975IF: 6.65
引用产品:CCK-8试剂盒 (RM02823)
Species:Homo sapiens
Application:Measurement of cell viability

Astaxanthin Augmented the AntiHepatocellular Carcinoma Efficacy of Sorafenib Through the Inhibition of the JAK2/STAT3 Signaling Pathway and Mitigation of

发表于《Molecular nutrition & food research》2023Pubmed ID:38059808IF: 6.57
引用产品:ECL Enhanced Kit {ECL化学发光底物(增强型)} (RM00021)
Species:Homo sapiens
Application:WB

Transcriptomics reveals apigenin alleviates airway inflammation and epithelial cell apoptosis in allergic asthma via MAPK pathway

发表于《Phytotherapy research : PTR》2023Pubmed ID:37128812IF: 6.38
引用产品:CCK-8试剂盒 (RM02823)
Species:Homo sapiens
Application:assess the viability of cultured cells

Endoplasmic Reticulum Stress Mediated NLRP3 Inflammasome Activation and Pyroptosis in THP-1 Macrophages Infected with Bacillus Calmette-Guérin - PMC

发表于《International journal of molecular sciences》2023Pubmed ID:37511451IF: 6.2
引用产品:ECL Enhanced Kit {ECL化学发光底物(增强型)} (RM00021)
Species:Homo sapiens
Application:WB

Canagliflozin Attenuates Lipotoxicity in Cardiomyocytes by Inhibiting Inflammation and Ferroptosis through Activating AMPK Pathway - PMC

发表于《International journal of molecular sciences》2023Pubmed ID:36614295IF: 6.2
引用产品:iNOS Rabbit pAb (A3200)
基因ID:4843
Species:Homo sapiens
Application:WB
引用产品:LKB1 Rabbit pAb (A2122)
基因ID:6794
Species:Homo sapiens
Application:WB
引用产品:Ferrostatin-1 (Fer-1) (RM02804)
Species:Homo sapiens
Application:Inhibitor
引用产品:CAMKK2 Rabbit pAb (A9899)
基因ID:10645
Species:Homo sapiens
Application:WB