Genetic manipulation of porcine deltacoronavirus reveals insights into NS6 and NS7 functions: a novel strategy for vaccine design.
Journal
Emerging Microbes & Infections
DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation
Biallelic variants in MAD2L1BP (p31comet) cause female infertility characterized by oocyte maturation arrest - PMC
Low concentrations of saracatinib promote definitive endoderm differentiation through inhibition of FAK-YAP signaling axis - PMC
Journal
Cell communication and signaling : CCS
The colonic pathogen Entamoeba histolytica activates caspase-4/1 that cleaves the pore-forming protein gasdermin D to regulate IL-1β secretion
Paclitaxel increases sensitivity of SKOV3 cells to hyperthermia by inhibiting heat shock protein 27
Journal
Biomed Pharmacother
The pyroptosis mechanism of ototoxicity caused by unconjugated bilirubin in neonatal hyperbilirubinemia
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis
Species
Homo sapiens, Mus musculus
RPLP2 activates TLR4 in an autocrine manner and promotes HIF-1-induced metabolic reprogramming in hepatocellular carcinoma - PMC
Journal
Cell death discovery
Comprehensive analysis of m6A modification in lipopolysaccharide-induced acute lung injury in mice - PMC
Journal
Molecular medicine (Cambridge, Mass.)
miR-29a-3p Regulates Autophagy by Targeting Akt3-Mediated mTOR in SiO2-Induced Lung Fibrosis - PMC
Journal
International journal of molecular sciences
DEL-1 deficiency aggravates pressure overload-induced heart failure by promoting neutrophil infiltration and neutrophil extracellular traps formation
Journal
Biochemical pharmacology
Dexamethasone causes calcium deposition and degeneration in human anterior cruciate ligament cells through endoplasmic reticulum stress
Journal
Biochemical Pharmacology
HDAC3 promotes macrophage pyroptosis via regulating histone deacetylation in acute lung injury - PMC
Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice - PMC
IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis - PMC
Spatiotemporal Expression of SphK1 and S1PR2 in the Hippocampus of Pilocarpine Rat Model and the Epileptic Foci of Temporal Lobe Epilepsy
Journal
Front Cell Dev Biol
DHAV-1 Blocks the Signaling Pathway Upstream of Type I Interferon by Inhibiting the Interferon Regulatory Factor 7 Protein
Novel Expression of EGFL7 in Osteosarcoma and Sensitivity to Cisplatin
Journal
Frontiers in Oncology
SETD7 regulates chondrocyte differentiation and glycolysis via the Hippo signaling pathway and HIF?1
Species
Homo sapiens, Mus musculus
VP4/VP56/VP35 Virus-like Particles Effectively Protect Grass Carp (Ctenopharyngodon idella) against GCRV-II Infection - PMC
Identification of fish CMPK2 as an interferon stimulated gene against SVCV infection
Journal
Fish & shellfish immunology
HSP70 positively regulates translation by interacting with the IRES and stabilizes the viral structural proteins VP1 and VP3 to facilitate duck hepatitis A virus type 1 replication - PMC
Journal
Veterinary research
A ferritin nanoparticle vaccine for foot-and-mouth disease virus elicited partial protection in mice
The Effects of Platelet-Rich and Platelet-Poor Plasma on Biological Characteristics of BM-MSCs In Vitro
Journal
Anal Cell Pathol (Amst)
DHAV 3CD targets IRF7 and RIG-I proteins to block the type I interferon upstream signaling pathway - PMC
Journal
Veterinary research
Mechanistic Insight on the Interaction between OPN and Integrin 3 in Osteoarthritis
Downregulation of DEC1 by RNA interference attenuates ischemia/reperfusion-induced myocardial inflammation by inhibiting the TLR4/NF-κB signaling pathway
Journal
Experimental and Therapeutic Medicine
A novel missense mutation (FGG c.1168G>T) in the gamma chain of fibrinogen causing congenital hypodysfibrinogenemia with bleeding phenotype - PMC
Coronavirus subverts ER-phagy by hijacking FAM134B and ATL3 into p62 condensates to facilitate viral replication - PMC
Species
Homo sapiens, Chlorocebus aethiops
TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
Journal
The Journal of biological chemistry
Species
Homo sapiens, Mus musculus
CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression - PMC
Journal
Cell death & disease
Lysine demethylase KDM1A promotes cell growth via FKBP8-BCL2 axis in hepatocellular carcinoma
Journal
The Journal of biological chemistry
Inactivated Pseudomonas PE(ΔIII) exotoxin fused to neutralizing epitopes of PEDV S proteins produces a specific immune response in mice