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Rabbit anti-Mouse IL-6 mAb(CAP) (RM17709)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

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货号: RM17709
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Mouse IL-6 mAb(CAP)
货号
RM17709
免疫原
Recombinant Mouse IL-6 Protein
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1,PH 7.4.
CrossReactivity
No cross-reactivity in ELISA with recombinant
mIL-6,hTNF,rIL-6,mIL-11
存储条件
Store at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Mouse IL-6 Sanwich ELISA Immunoassay

 Recommended
Concentration
Sample
ELISA Capture0.5-2ug/mLRabbit anti-Mouse IL-6(CAP)(Cat. No.RM17709)
ELISA Detection0.0125-0.05ug/mLRabbit anti-Mouse IL-6(CAP)(Cat. No.RM17710)
Standard7.81-500pg/mLRecombinant Mouse IL-6 Protein

背景信息

Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates "classic signaling", the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates "trans-signaling". Alternatively, "cluster signaling" occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.

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