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* This package insert must be read in its entirety before using this product.
Human CD141 Sandwich ELISA Immunoassay
Recommended Concentration | Sample | |
---|---|---|
ELISA Capture | 1-4ug/mL | Rabbit anti-Human CD141(CAP)(Cat. No.RM177788) |
ELISA Detection | 0.00625-0.025ug/mL | Rabbit anti-Human CD141(DET)(Cat. No.RM17789) |
Standard | 31.25-2000pg/mL | Recombinant Human CD141 Protein |
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.