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Rabbit anti-Human Ghrelin mAb(CAP) (RM18049)

This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.

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货号: RM18049
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Human Ghrelin mAb(CAP)
货号
RM18049
免疫原
Recombinant Human Ghrelin
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
CrossReactivity
/
存储条件
Store at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human Ghrelin Sandwich ELISA Immunoassay

 Recommended
Concentration
Sample
ELISA Capture2-8ug/mLRabbit anti-Human Ghrelin mAb(CAP)(Cat. No.RM18049)
ELISA Detection0.008-0.032ug/mLRabbit anti-Human Ghrelin mAb(DET)(Cat. No.RM18050)
Standard0.16-10ng/mLRecombinant Human Ghrelin Protein

背景信息

This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.

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