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Human VEGFR2/Flk-1 Sandwich ELISA Immunoassay
Recommended Concentration | Sample | |
---|---|---|
ELISA Capture | 1-4ug/mL | Rabbit anti-Human VEGFR2/Flk-1 mAb(CAP)(Cat. No.RMK0019 ) |
ELISA Detection | 0.25-1ug/mL | Rabbit anti-Human VEGFR2/Flk-1 mAb(DET)(Cat. No.RMK0020 ) |
Standard | 78.13-5000pg/mL | Recombinant Human VEGFR2/Flk-1 Protein(Cat. No.RP00084) |
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.