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Mouse IL-12 multiplex assay
Recommended Concentration | Sample | |
---|---|---|
Multiplex Capture | 3-20ug/mL | Rabbit anti-Mouse IL-12 mAb(Cat. No.RM17756) |
Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Mouse IL-12 mAb(Cat. No.RMK0323) |
Standard | 6.86-5000pg/mL | Recombinant Mouse IL-12 Protein |
Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells