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Human IL-1 alpha multiplex assay
Recommended Concentration | Sample | |
---|---|---|
Multiplex Capture | 3-20ug/mL | Rabbit anti-Human IL-1 alpha mAb(Cat. No.RMK0351) |
Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human IL-1 alpha mAb(Cat. No.RMK0352) |
Standard | 6.86-5000pg/mL | Recombinant Human IL-1 alpha Protein |
Interleukin 1 (IL-1) is a name that designates two proteins, IL-1 alpha and IL-1 beta, which are the products of distinct genes, but which show approximately 25% amino acid sequence identity and which recognize the same cell surface receptors. Although IL-1 production is generally considered to be a consequence of inflammation, recent evidence suggests that IL-1 is also temporarily upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. In response to classic stimuli produced by inflammatory agents, infections or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cells is seen