产品中心 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
Standard Curve Chart
* This package insert must be read in its entirety before using this product.
Human uPAR multiplex assay
| Recommended Concentration | Sample | |
|---|---|---|
| Multiplex Capture | 3-20ug/mL | Rabbit anti-Human uPAR mAb(Cat. No.RMK0373) |
| Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human uPAR mAb(Cat. No.RMK0374) |
| Standard | 6.86-5000pg/mL | Recombinant Human uPAR Protein |
The urokinase-type Plasminogen Activator Receptor (uPAR) is a GPI-anchored protein that binds to both the inactive and active forms of uPA. This interaction serves to localize and enhance the proteolytic activity of uPA, leading to increased conversion of Plasminogen to Plasmin. uPA also triggers uPAR-mediated signal transduction, activation of protein tyrosine kinases, gene expression, cell adhesion, and chemotaxis. uPAR can additionally regulate cell adhesion by direct binding to Vitronectin and preventing Integrins from binding to their ligands.
