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Human Endoglin/CD105 multiplex assay
| Recommended Concentration | Sample | |
|---|---|---|
| Multiplex Capture | 3-20ug/mL | Rabbit anti-Human Endoglin/CD105 mAb(Cat. No.RMK0381) |
| Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human Endoglin/CD105 mAb(Cat. No.RMK0382) |
| Standard | 6.86-5000pg/mL | Recombinant Human Endoglin/CD105 Protein |
Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins (1-3). Endoglin and Betaglycan/T beta RIII are type III receptors for TGF beta superfamily ligands, sharing 71% aa identity in the transmembrane (TM) and cytoplasmic domains. Endoglin is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta, with lower amounts on hematopoietic, mesenchymal and neural crest stem cells, activated monocytes, and lymphoid and myeloid leukemic cells
