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Standard Curve Chart
* This package insert must be read in its entirety before using this product.
Human IL-6R multiplex assay
| Recommended Concentration | Sample | |
|---|---|---|
| Multiplex Capture | 3-20ug/mL | Rabbit anti-Human IL-6R mAb(Cat. No.RMK0393) |
| Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human IL-6R mAb(Cat. No.RMK0196) |
| Standard | 6.86-5000pg/mL | Recombinant Human IL-6R Protein |
The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha ) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed
