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Rabbit anti- Human TRAIL/TNFSF10 mAb (RMK0437)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

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货号: RMK0437
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti- Human TRAIL/TNFSF10 mAb
货号
RMK0437
免疫原
Recombinant Human TRAIL/TNFSF10
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
CrossReactivity
/
存储条件
Store at -20℃.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human TRAIL/TNFSF10 ELISA

  Recommended
Concentration
Sample
ELISACapture0.5-2ug/mLRabbit anti-Human TRAIL/TNFSF10 mAb (Cat. No.RMK0437)
Detection0.05-0.2ug/mLRabbit anti-Human TRAIL/TNFSF10 mAb (Cat. No.RMK0438)
Standard15.63-1000pg/mLRecombinant Human TRAIL/TNFSF10 Protein

背景信息

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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