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Recombinant Mouse CXCL13/BLC Protein was determined by SDS-PAGE with Coomassie Blue, RP02941LQ was determined by SDS-PAGE with Coomassie Blue, showing a band at 16-20 kDa.
The purity of Mouse CXCL13/BLC Protein (Cat.RP02941LQ) was greater than 95% as determined by SEC-HPLC.
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
