Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
Journal
Nature communications
RNAi Screening Identifies that TEX10 Promotes the Proliferation of Colorectal Cancer Cells by Increasing NF‐κB Activation
Structural analysis and attenuates hyperuricemic nephropathy of dextran from the Imperata cylindrica Beauv. var. major (Nees) CE Hubb.
Journal
Carbohydrate polymers
Layered Double Hydroxide Nanoparticles with Osteogenic Effects as miRNA Carriers to Synergistically Promote Osteogenesis of MSCs
Journal
ACS Appl Mater Interfaces
Species
Mus musculus,Rattus norvegicus
Porcine TLR8 signaling and its anti-infection function are disturbed by immune checkpoint receptor TIM-3 via inhibition of P13K-AKT pathway
Journal
International journal of biological macromolecules
Discovery of the First Subnanomolar PPARα/δ Dual Agonist for the Treatment of Cholestatic Liver Diseases
Journal
Journal of medicinal chemistry
CRM197-conjugated multi antigen dominant epitope for effective human cytomegalovirus vaccine development
Journal
International journal of biological macromolecules
Species
Homo sapiens, Mus musculus
Ink melanin from Sepiapharaonis ameliorates colitis in mice via reducing oxidative stress, andprotecting the intestinal mucosal barrier
Role of Clusterin/NF-κB in the secretion of senescence-associated secretory phenotype in Cr (VI)-induced premature senescent L-02 hepatocytes
Journal
Ecotoxicology and environmental safety
Design, synthesis, and biological evaluation of a novel dual peroxisome proliferator-activated receptor alpha/delta agonist for the treatment of diabetic kidney disease through anti-inflammatory mechanisms
Loganin inhibits macrophage M1 polarization and modulates sirt1/NF-B signaling pathway to attenuate ulcerative colitis
Chemokine (C-C motif) ligand 18/membrane-associated 3/forkhead box O1 axis promotes the proliferation, migration, and invasion of intrahepatic cholangiocarcinoma
Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization
Protective effects of E Se tea extracts against alcoholic fatty liver disease induced by high fat/alcohol diet: In vivo biological evaluation and molecular docking study
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Porcine deltacoronavirus accessory protein NS6 antagonizes IFN-β production by interfering with the binding of RIG-I/MDA5 to double-stranded RNA
Journal
Journal of virology
The Antitumoral/Antimetastatic Action of the Flavonoid Brachydin A in Metastatic Prostate Tumor Spheroids In Vitro Is Mediated by (Parthanatos) PARP-Related Cell Death
A Comparative Analysis of Edwardsiella tarda-Induced Transcriptome Profiles in RAW264.7 Cells Reveals New Insights into the Strategy of Bacterial Immune Evasion.
Journal
International Journal of Molecular Sciences
Species
Mus musculus,Edwardsiella tarda
Transcriptomic Evidence of Hypothalamus for Maternal Fructose Exposure Induced Offspring Hypertension through AT1R/TLR4 Pathway
Journal
The Journal of nutritional biochemistry
Whitening of brown adipose tissue inhibits osteogenic differentiation via secretion of S100A8/A9 - PMC
Schisandrol B protects against cholestatic liver injury by inhibiting pyroptosis through pregnane X receptor
Journal
Biochemical pharmacology
Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling - PMC
Journal
Frontiers in pharmacology
Astroglia proliferate upon the biogenesis of tunneling nanotubes via -synuclein dependent transient nuclear translocation of focal adhesion kinase - PMC
Loganin alleviates sepsis-induced acute lung injury by regulating macrophage polarization and inhibiting NLRP3 inflammasome activation
Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway
Journal
Int Immunopharmacol
Comparison of the Antioxidant and Cytoprotective Properties of Extracts from Different Cultivars of Cornus mas L. - PMC
Journal
International journal of molecular sciences
Role of Ciminalum-4-thiazolidinone Hybrids in Molecular NF-B Dependent Pathways - PMC
Journal
International journal of molecular sciences
Diverse Galactooligosaccharides Differentially Reduce LPS-Induced Inflammation in Macrophages - PMC
Journal
Foods (Basel, Switzerland)
CALML6 Controls TAK1 Ubiquitination and Confers Protection against Acute Inflammation
Journal
Journal of Immunology (Baltimore, Md. : 1950)
Biomimetic synthesis and anti-inflammatory evaluation of violacin A analogues
Journal
Bioorganic chemistry
Inula japonica ameliorated bleomycin-induced pulmonary fibrosis via inhibiting soluble epoxide hydrolase
Journal
Bioorganic chemistry
Structural modification of natural axinelline A: Achieving reduced colitis side effects through balanced COX inhibition
Journal
Bioorganic chemistry
EEBR induces Caspase-1-dependent pyroptosis through the NF-B/NLRP3 signalling cascade in non-small cell lung cancer - PMC
Journal
Journal of cellular and molecular medicine
Effects of ammonia exposure on antioxidant function, immune response and NF-κB pathway in Chinese Strip-necked Turtle (Mauremys sinensis)
Study on the effect of active components of Schisandra chinensis on liver injury and its mechanisms in mice based on network pharmacology
Anneslea fragrans Wall. ameliorates ulcerative colitis via inhibiting NF-κB and MAPK activation and mediating intestinal barrier integrity
Tectorigenin inhibits inflammation and pulmonary fibrosis in allergic asthma model of ovalbumin-sensitized guinea pigs
Journal
The Journal of Pharmacy and Pharmacology
Therapeutic Effect of CC Chemokine Receptor Type 1 (CCR1) Antagonist BX471 on Allergic Rhinitis
Saikosaponin a attenuates lead-induced kidney injury through activating Nrf2 signaling pathway
Journal
Comparative Biochemistry And Physiology C-Toxicology & Pharmacology
Differential expression of microRNAs in human endometrium after implantation of an intrauterine contraceptive device containing copper
Journal
Molecular human reproduction
Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses
Journal
Toxicol Appl Pharmacol
Tectoridin alleviates lipopolysaccharide-induced inflammation via inhibiting TLR4-NF-κB/NLRP3 signaling in vivo and in vitro
Journal
Immunopharmacology and immunotoxicology
Corynoline ameliorates dextran sulfate sodium-induced colitis in mice by modulating Nrf2/NF-κB pathway
Journal
Immunopharmacology and immunotoxicology
Porcine deltacoronavirus nsp10 antagonizes interferon-β production independently of its zinc finger domains
Circular RNA circ_0068, 888 protects against lipopolysaccharide-induced HK-2 cell injury via sponging microRNA-21–5p
Journal
Biochemical and biophysical research communications
Celastrol Attenuates Learning and Memory Deficits in an Alzheimer's Disease Rat Model
Accelerated Wound Healing in Diabetic Rat by miRNA-185-5p and Its Anti-Inflammatory Activity - PMC
Journal
Diabetes, metabolic syndrome and obesity : targets and therapy
Species
Homo sapiens,Rattus norvegicus
Toxoplasma gondii rhoptry protein (TgROP18) enhances the expression of pro-inflammatory factor in LPS/IFN--induced murine BV2 microglia cells via NF-B signal
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway
Journal
Journal of cardiovascular translational research
Ginkgo biloba Extract Attenuates Methotrexate-Induced Testicular Injury in Rats: Cross-talk Between Oxidative Stress, Inflammation, Apoptosis, and miRNA-29a Expression
Journal
Integr Cancer Ther
Suffrutines A and B Inhibit the Expression of Inflammatory Mediators in LPS-Induced RAW264. 7 Cells by Suppressing the NF-B Signaling Pathway
Protective mechanism of selenium on mercuric chloride-induced testis injury in chicken via p38 MAPK/ATF2/iNOS signaling pathway
Japanese encephalitis virus induces apoptosis by activating the RIG-1 signaling pathway
Journal
Archives of virology
Protective Effects of Anwulignan against HCl/Ethanol-Induced Acute Gastric Ulcer in Mice
Journal
Evid Based Complement Alternat Med
Effect of Xanthii Fructus alcohol extract on proliferation and apoptosis of HFLS-RA and its mechanism - PMC
MIR155HG Plays a Bivalent Role in Regulating Innate Antiviral Immunity by Encoding Long Noncoding RNA-155 and microRNA-155-5p