Biotinylated Human Siglec-3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human Siglec-3 is greater than 90% as determined by SEC-HPLC.
Immobilized Biotinylated Human Siglec-3, His Tag at 0.5 μg/mL (100 μL/Well) on streptavidin (5 μg/mL) precoated plate. Dose response curve for Anti-Siglec-3 Antibody, hFc Tag with the EC50 of 4.4ng/mL determined by ELISA.
Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs.
