Proto-oncogene tyrosine-protein kinase Src, also known as c-Src, is a non-receptor tyrosine kinase protein that in humans is encoded by the SRC gene. It includes an SH2 domain, an SH3 domain and a tyrosine kinase domain. When src is activated, it promotes survival, angiogenesis, proliferation and invasion pathways. It also regulates angiogenic factors and vascular permeability after focal cerebral ischemia-reperfusion, and regulates matrix metalloproteinase-9 activity after intracerebral hemorrhage.