miR-29b contributes to multiple types of muscle atrophy
Journal
Nature communications
Inhibition of lncRNA MAAT controls multiple types of muscle atrophy by cis-and trans-regulatory actions
Journal
Molecular therapy : the journal of the American Society of Gene Therapy
CRISPR/Cas9-mediated miR-29b editing as a treatment of different types of muscle atrophy in mice
Journal
Molecular therapy : the journal of the American Society of Gene Therapy
α-synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson's disease
Serum and glucocorticoid-regulated kinase 1 regulates transforming growth factor β1-connective tissue growth factor pathway in chronic rhinosinusitis
Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b
Journal
Mol Ther Nucleic Acids
Metformin synergistically enhances the antitumour activity of Lenvatinib in hepatocellular carcinoma by altering AKT‐FOXO3 signalling pathway
Journal
Liver international : official journal of the International Association for the Study of the Liver
GL-V9 exerts anti-T cell malignancies effects via promoting lysosome-dependent AKT1 degradation and activating AKT1/FOXO3A/BIM axis.
Journal
Free radical biology & medicine
Species
Homo sapiens, Mus musculus
Microbiota-derived 3-phenylpropionic acid promotes myotube hypertrophy by Foxo3/NAD+ signaling pathway - PMC
Microbiota-derived 3-phenylpropionic acid promotes myotube hypertrophy by Foxo3/NAD+ signaling pathway - PMC
Maternal inulin supplementation ameliorates prenatal methamphetamine exposure-induced hepatotoxicity and restores gut microbiota in mouse offspring
Journal
Ecotoxicology and environmental safety
LIPUSSCsExo promotes peripheral nerve regeneration in cavernous nerve crush injuryinduced ED rats via PI3K/Akt/FoxO signaling pathway
Journal
CNS neuroscience & therapeutics
5-Heptadecylresorcinol attenuates oxidative damage and mitochondria-mediated apoptosis through activation of the SIRT3/FOXO3a signaling pathway in neurocytes
The Aneugenicity of Ketone Bodies in Colon Epithelial Cells Is Mediated by Microtubule Hyperacetylation and Is Blocked by Resveratrol
Journal
International journal of molecular sciences
Combined metabolomic and transcriptomic profiling approaches reveal the cardiac response to high-fat diet
Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
5-Heptadecylresorcinol Ameliorates Obesity-Associated Skeletal Muscle Mitochondrial Dysfunction through SIRT3-Mediated Mitophagy
Journal
Journal of agricultural and food chemistry
Pregestational diabetes alters cardiac structure and function of neonatal rats through developmental plasticity - PMC
Journal
Frontiers in cardiovascular medicine
Syringin exerts neuroprotective effects in a rat model of cerebral ischemia through the FOXO3a/NF-B pathway
Journal
Int Immunopharmacol
Andrographolide attenuates oxidative stress injury in cigarette smoke extract exposed macrophages through inhibiting SIRT1/ERK signaling
Journal
International Immunopharmacology
Nobiletin restores HFD-induced enteric nerve injury by regulating enteric glial activation and the GDNF/AKT/FOXO3a/P21 pathway - PMC
Journal
Molecular medicine (Cambridge, Mass.)
Forkhead Transcription Factor 3a (FOXO3a) Modulates Hypoxia Signaling via Up-regulation of the von Hippel-Lindau Gene (VHL)
Journal
Journal of biological chemistry
Andrographolide attenuates epithelial‐mesenchymal transition induced by TGF‐β1 in alveolar epithelial cells
The molecular neural mechanism underlying the acceleration of brain aging due to Dcf1 deficiency
Journal
Molecular and cellular neurosciences
Gallic Acid Can Promote Low-Density Lipoprotein Uptake in HepG2 Cells via Increasing Low-Density Lipoprotein Receptor Accumulation - PMC
Journal
Molecules (Basel, Switzerland)
Promoting effects of calponin 3 on the growth of diffuse large B-cell lymphoma cells - PMC
Running Improves Muscle Mass by Activating Autophagic Flux and Inhibiting Ubiquitination Degradation in Mdx Mice
Catechin attenuates TNF-α induced inflammatory response via AMPK-SIRT1 pathway in 3T3-L1 adipocytes.
Activation of SIRT3 attenuates triptolide-induced toxicity through closing mitochondrial permeability transition pore in cardiomyocytes
Journal
Toxicology in vitro
Piceatannol alleviate ROS‐mediated PC‐12 cells damage and mitochondrial dysfunction through SIRT3/FOXO3a signaling pathway
Downregulation of AMPK dependent FOXO3 and TFEB involves in the inhibition of autophagy in diabetic cataract