Spatiotemporal regulation of insulin signaling by liquid-liquid phase separation - PMC
Species
Chlorocebus aethiops
Unspliced XBP1 Counteracts -Catenin to Inhibit Vascular Calcification
Journal
Circulation Research
High mobility group AT-hook 1 (HMGA1) is an important positive regulator of hepatitis B virus (HBV) that is reciprocally upregulated by HBV X protein
Journal
Nucleic acids research
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock
Journal
Nature Communications
Nuclear cGAS restricts L1 retrotransposition by promoting TRIM41-mediated ORF2p ubiquitination and degradation - PMC
Journal
Nature communications
Porcine reproductive and respiratory syndrome virus degrades DDX10 via SQSTM1/p62-dependent selective autophagy to antagonize its antiviral activity
K48-linked deubiquitination of VGLL4 by USP15 enhances the efficacy of tumor immunotherapy in triple-negative breast cancer
Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression
Journal
Cell death & disease
IP-10 Promotes Blood-Brain Barrier Damage by Inducing Tumor Necrosis Factor Alpha Production in Japanese Encephalitis
Journal
Frontiers in Immunology
The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN-β Production by Targeting TNF Receptor-Associated Factor 3.
Journal
Frontiers in Immunology
Gαq-PKD/PKCμ signal regulating the nuclear export of HDAC5 to induce the IκB expression and limit the NF-κB-mediated inflammatory response essential for early pregnancy - PMC
GL-V9 exerts anti-T cell malignancies effects via promoting lysosome-dependent AKT1 degradation and activating AKT1/FOXO3A/BIM axis.
Journal
Free radical biology & medicine
Species
Homo sapiens, Mus musculus
Etanercept reduces neuroinflammation and lethality in mouse model of Japanese encephalitis
Journal
Journal of infectious diseases
Inhibition of Wnt/β-catenin pathway reverses multi-drug resistance and EMT in Oct4 +/Nanog + NSCLC cells
Journal
Biomed Pharmacother
6-Methyl flavone inhibits Nogo-B expression and improves high fructose diet-induced liver injury in mice
Journal
Acta pharmacologica Sinica
Glabridin Ameliorates Alcohol-Caused Liver Damage by Reducing Oxidative Stress and Inflammation via p38 MAPK/Nrf2/NF-B Pathway - PMC
MicroRNA-19b-3p Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF11
Journal
Journal of Virology
Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB
Journal
Journal of Virology
Oroxylin A increases the sensitivity of temozolomide on glioma cells by hypoxia-inducible factor 1α/hedgehog pathway under hypoxia.
Journal
Journal of cellular physiology
cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model - PMC
Region-specific heterogeneity in neuronal nuclear morphology in young, aged and in Alzheimers disease mouse brains - PMC
Journal
Frontiers in cell and developmental biology
Porcine Deltacoronavirus Accessory Protein NS7a Antagonizes IFN-β Production by Competing With TRAF3 and IRF3 for Binding to IKKε
Journal
Front Cell Infect Microbiol
p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes
Journal
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
lncRNA HCG11 suppresses cell proliferation in hormone receptor-positive breast cancer via SRSF1/β-catenin - PMC
CLIC4 regulates radioresistance of nasopharyngeal carcinoma by iNOS after γ-rays but not carbon ions irradiation
Inhibition of neutrophil elastase prevents cigarette smoke exposure-induced formation of neutrophil extracellular traps and improves lung function in a mouse …
Journal
International immunopharmacology
Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression
MicroRNA-15b Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF125
Journal
Journal of Immunology
Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus - PMC
Journal
Journal of virology
Species
Homo sapiens,Mus musculus
Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-induced Innate Immunity
Quantitative Label-Free Phosphoproteomics Reveals Differentially Regulated Protein Phosphorylation Involved in West Nile Virus-Induced Host Inflammatory Response
Journal
Journal Of Proteome Research
The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma
Transcriptional regulation of miR-15b by c-Rel and CREB in Japanese encephalitis virus infection
Journal
Scientific Reports
miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes
Journal
Cellular Signalling
Paclitaxel combined with Compound K inducing pyroptosis of non-small cell lung cancer cells by regulating Treg/Th17 balance - PMC
Bai-He-Gu-Jin-Tang formula suppresses lung cancer via AKT/GSK3β/β-catenin and induces autophagy via the AMPK/mTORC1/ULK1 signaling pathway
Lymphatic Metastasis of NSCLC Involves Chemotaxis Effects of Lymphatic Endothelial Cells through the CCR7–CCL21 Axis Modulated by TNF-α
Expression of lamin A/C protein in degenerated human intervertebral disc.
Journal
European review for medical and pharmacological sciences
MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS)
Translocator Protein (TSPO) Alleviates Neuropathic Pain by Activating Spinal Autophagy and Nuclear SIRT1/PGC-1α Signaling in a Rat L5 SNL Model
Journal
Journal of pain research
The effect of cellular nuclear function alteration on the pathogenesis of shoulder adhesive capsulitis: an immunohistochemical study on lamin A/C expression - PMC
Journal
Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
Wenshen Shengjing Decoction Improves Early Embryo Development by Maintaining Low H3K27me3 Levels in Sperm and Pronuclear Embryos of Spermatogenesis Impaired Mice
Journal
Evid Based Complement Alternat Med