Usp7 regulates Hippo pathway through deubiquitinating the transcriptional coactivator Yorkie.
Journal
Nature communications
Nicotine rebalances NAD+ homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity - PMC
Journal
Nature communications
Genetic Aberrations and Interaction of NEK2 and TP53 Accelerate Aggressiveness of Multiple Myeloma
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Engineering Alendronate-Composed Iron Nanochelator for Efficient Peritoneal Carcinomatosis Treatment - PMC
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
The protective effects of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice.
Journal
International journal of antimicrobial agents
Wireless Electric Cues Mediate Autologous DPSCLoaded Conductive Hydrogel Microspheres to Engineer The ImmunoAngiogenic Niche for Homologous
Journal
Advanced healthcare materials
Species
Homo sapiens,Rattus norvegicus
NFAT5 is Regulated by p53/miR-27a Signal Axis and Promotes Mouse Ovarian Granulosa Cells Proliferation.
Journal
International journal of biological sciences
The therapeutic effect of Tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products
Journal
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Systems Immunology Analysis Reveals an Immunomodulatory Effect of Snail-p53 Binding on Neutrophil- and T Cell-Mediated Immunity in KRAS Mutant Non-Small Cell Lung Cancer
The Molecular Evolution and Functional Divergence of Lamprey Programmed Cell Death Genes.
Journal
Frontiers in Immunology
Metabolic rescue ameliorates mitochondrial encephalo-cardiomyopathy in murine and human iPSC models of Leigh syndrome - PMC
Journal
Clinical and translational medicine
Species
Homo sapiens, Mus musculus
3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory …
Journal
Biomedical journal
High-Carbohydrate Diet Alleviates the Oxidative Stress, Inflammation and Apoptosis of Megalobrama amblycephala Following Dietary Exposure to Silver Nanoparticles
Journal
Antioxidants (Basel)
Species
Megalobrama amblycephala
Potential cardioprotective effects of Amentoflavone in doxorubicin-induced cardiotoxicity in mice
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
Journal
Acta Pharmacol Sin
Role of Clusterin/NF-κB in the secretion of senescence-associated secretory phenotype in Cr (VI)-induced premature senescent L-02 hepatocytes
Journal
Ecotoxicology and environmental safety
MDM2-p53 mediate a miR-181c-3p/LIF axis to regulate low dose-rate radiation-induced DNA damage in human B lymphocytes
Journal
Ecotoxicology and environmental safety
Small nucleolar RNA 42 promotes the growth of hepatocellular carcinoma through the p53 signaling pathway
Species
Homo sapiens, Mus musculus
Upregulation of Oxidative stress-responsive 1 (OXSR1) Predicts Poor Prognosis and Promotes Hepatocellular Carcinoma Progression
Induction of systemic immune responses and reversion of immunosuppression in the tumor microenvironment by a therapeutic vaccine for cervical cancer
Journal
Cancer Immunol Immunother
CircRAD23B promotes proliferation and carboplatin resistance in ovarian cancer cell lines and organoids - PMC
Journal
Cancer cell international
Inhibition of DRP-1-Dependent Mitophagy Promotes Cochlea Hair Cell Senescence and Exacerbates Age-Related Hearing Loss.
Journal
Frontiers in Cellular Neuroscience
20-Deoxyingenol alleviates intervertebral disc degeneration by activating TFEB in nucleus pulposus cells
Journal
Biochemical pharmacology
Telomeres cooperate in zygotic genome activation by affecting DUX4/Dux transcription - PMC
Cisplatin causes erectile dysfunction by decreasing endothelial and smooth muscle content and inducing cavernosal nerve senescence in rats - PMC
Journal
Frontiers in endocrinology
Klotho-derived peptide KP1 ameliorates SARS-CoV-2-associated acute kidney injury - PMC
Journal
Frontiers in pharmacology
SUV39H2/KMT1B Inhibits the cardiomyocyte senescence phenotype by down-regulating BTG2/PC3
Adipose-derived mesenchymal stem cells-derived exosome-mediated microRNA-342-5p protects endothelial cells against atherosclerosis
Searching for novel MDM2/MDMX dual inhibitors through a drug repurposing approach
Journal
Journal of enzyme inhibition and medicinal chemistry
Phosphorylation of MITF by AKT affects its downstream targets and causes TP53-dependent cell senescence
Journal
The international journal of biochemistry & cell biology
Transcription factor C/EBPβ and 17β-estradiol promote transcription of the porcine p53 gene
Journal
The international journal of biochemistry & cell biology
LRRC8A promotes Glaesserella parasuis cytolethal distending toxin-induced p53-dependent apoptosis in NPTr cells
Discovery of linear unnatural peptides as potent mutant isocitrate dehydrogenase 1 inhibitors by Ugi reaction
Zeaxanthin prevents ferroptosis by promoting mitochondrial function and inhibiting the p53 pathway in free fatty acid-induced HepG2 cells
Journal
Biochimica et biophysica acta. Molecular and cell biology of lipids
5-Iodotubercidin Inhibits the Growth of Insulinoma Cells by Inducing Apoptosis
Journal
Neuroendocrinology
Proanthocyanidins Alleviates AflatoxinB1-Induced Oxidative Stress and Apoptosis through Mitochondrial Pathway in the Bursa of Fabricius of Broilers.
Urolithin A attenuates auditory cell senescence by activating mitophagy
Journal
Scientific reports
Dihydrotanshinone I Enhances Cell Adhesion and Inhibits Cell Migration in Osteosarcoma U-2 OS Cells through CD44 and Chemokine Signaling - PMC
Journal
Molecules (Basel, Switzerland)
Natural compound library screening identifies Sanguinarine chloride for the treatment of SCLC by upregulating CDKN1A
Journal
Translational oncology
GD2 CAR-T cells in combination with Nivolumab exhibit enhanced antitumor efficacy - PMC
Journal
Translational oncology
The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53/p21/RB pathway
Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53.
Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat.
Journal
Toxicology Letters
Iron overload causes macrophages to produce a proinflammatory phenotype in the synovium of hemophiliac arthritis via the acetylp53 pathway
Journal
Haemophilia : the official journal of the World Federation of Hemophilia
Transcriptional Regulation of CD40 Expression by 4 Ribosomal Proteins via a Functional SNP on a Disease-Associated CD40 Locus
Lymphatic Metastasis of NSCLC Involves Chemotaxis Effects of Lymphatic Endothelial Cells through the CCR7–CCL21 Axis Modulated by TNF-α
Mechanisms of hedgehog, calcium and retinoic acid signalling pathway inhibitors: Plausible modes of action along the MLL–EZH2-p53 axis in cellular growth control
Journal
Archives of biochemistry and biophysics
MiR4943p aggravates pirarubicininduced cardiomyocyte injury by regulating MDM4/p53 signaling pathway
Journal
Environmental toxicology
Finding an efficient tetramethylated hydroxydiethylene of resveratrol analogue for potential anticancer agent
A pilot study comparing the genetic molecular biology of gestational and non-gestational choriocarcinoma
Journal
American Journal of Translational Research
Effect of astaxanthin on apoptosis of rat renal tubular epithelial cells induced by iohexol.
Journal
American journal of translational research
AURKA suppression induces DU145 apoptosis and sensitizes DU145 to docetaxel treatment
Journal
American Journal Of Translational Research
Comparison of toxicity of benzene metabolite hydroquinone in hematopoietic stem cells derived from murine embryonic yolk sac and adult bone marrow
Species
Homo sapiens, Mus musculus
E2F1 inhibits cellular senescence and promotes oxaliplatin resistance in colorectal cancer - PMC
Journal
Annals of translational medicine
Inhibition of Orthotopic Genital Cancer Induced by Subcutaneous Administration of Human Papillomavirus Peptide Vaccine with CpG Oligodeoxynucleotides as an Adjuvant in Mice
Chrysophanol attenuates hepatitis B virus X protein-induced hepatic stellate cell fibrosis by regulating endoplasmic reticulum stress and ferroptosis
Journal
Journal of pharmacological sciences
Upregulation of Excision Repair Cross-Complementation Group 6-Like (ERCC6L) Promotes Tumor Growth in Hepatocellular Carcinoma
Journal
Digestive Diseases and Sciences
Extrinsic apoptosis and senescence involve in growth kinetics of seminoma to cisplatin
Journal
Clinical and experimental pharmacology & physiology
Aristolochic acid I induces impairment in spermatogonial stem cell in rodents
Journal
Toxicology research
Long-term repetitive exposure to excess iodine induces mitochondrial apoptosis, and alters monoamine neurotransmitters in hippocampus of rats of different genders
Journal
Toxicol Res (Camb)
Mechanism of YAP1 in the senescence and degeneration of endplate chondrocytes induced by intermittent cyclic mechanical tension - PMC
Journal
Journal of orthopaedic surgery and research
Comparative analysis of mouse embryonic palatal mesenchymal cells isolated by two primary culture methods
Systematic screen with kinases inhibitors reveals kinases play distinct roles in growth of osteoprogenitor cells
Journal
International Journal Of Clinical and Experimental Pathology
KAT5 silencing induces apoptosis of GBC-SD cells through p38MAPK-mediated upregulation of cleaved Casp9
Journal
International Journal Of Clinical and Experimental Pathology
Brazilin Isolated from Caesalpina Sappan Wood Induces Intrinsic Apoptosis on A549 Cancer Cell Line by Increasing p53, caspase-9, and caspase-3
Journal
Asian Pacific journal of cancer prevention : APJCP