Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas
Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor
EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses - PMC
Journal
Nature communications
Highly Mimetic Ex Vivo LungCancer SpheroidBased Physiological Model for Clinical Precision Therapeutics
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Biological activities of siRNA-loaded lanthanum phosphate nanoparticles on colorectal cancer
Enhanced cancer therapeutic efficiency of NO combined with siRNA by caspase-3 responsive polymers
Journal
Journal of controlled release : official journal of the Controlled Release Society
Combined negative effects of microplastics and plasticizer DEHP: The increased release of Nets delays wound healing in mice
Journal
The Science of the total environment
The deubiquitinase USP2a promotes tumor immunosuppression by stabilizing immune checkpoint B7-H4 in lung adenocarcinoma harboring EGFR-activating mutants
Co-loaded lapatinib/PAB by ferritin nanoparticles eliminated ECM-detached cluster cells via modulating EGFR in triple-negative breast cancer - PMC
Journal
Cell death & disease
Engineering alginate/carboxymethylcellulose scaffolds to establish liver cancer spheroids: Evaluation of molecular variances between 2D and 3D models
Journal
International journal of biological macromolecules
Selenoprotein W Ameliorates Experimental Colitis and Promotes Intestinal Epithelial Repair - PMC
Journal
Antioxidants (Basel, Switzerland)
Gossypol overcomes EGFR-TKIs resistance in non-small cell lung cancer cells by targeting YAP/TAZ and EGFRL858R/T790M.
Journal
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie
HDGF promotes gefitinib resistance by activating the PI3K/AKT and MEK/ERK signaling pathways in non-small cell lung cancer - PMC
Journal
Cell death discovery
Targeted Co-Delivery of Gefitinib and Rapamycin by Aptamer-Modified Nanoparticles Overcomes EGFR-TKI Resistance in NSCLC via Promoting Autophagy - PMC
Journal
International journal of molecular sciences
Targeting cuproptosis by zinc pyrithione in triple-negative breast cancer - PMC
Network Pharmacology and Molecular Docking-Based Investigation: Prunus mume Against Colorectal Cancer via Silencing RelA Expression
LY2874455 and Abemaciclib Reverse FGF3/4/19/CCND1 Amplification Mediated Gefitinib Resistance in NSCLC - PMC
Journal
Frontiers in pharmacology
NONO phase separation enhances DNA damage repair by accelerating nuclear EGFR-induced DNA-PK activation
Exploring the Mechanism of Hawthorn Leaves Against Coronary Heart Disease Using Network Pharmacology and Molecular Docking - PMC
Journal
Frontiers in cardiovascular medicine
QKI-6 Suppresses Cell Proliferation, Migration, and EMT in Non-Small Cell Lung Cancer
Journal
Frontiers in oncology
Discovery of a potential bladder cancer inhibitor CHNQD-01281 by regulating EGFR and promoting infiltration of cytotoxic T cells - PMC
Journal
Marine life science & technology
Exploration of novel dihydroquinoxalinone derivatives as EGFRL858R/T790M tyrosine kinase inhibitors for the treatment of non-small-cell lung cancer
Journal
Bioorganic chemistry
Kaempferol suppresses glioma progression and synergistically enhances the antitumor activity of gefitinib by inhibiting the EGFR/SRC/STAT3 signaling pathway
Journal
Drug development research
EGFR inhibition reverses resistance to lenvatinib in hepatocellular carcinoma cells
Journal
Scientific reports
Network pharmacology combined with experimental verification to explore the potential mechanism of naringenin in the treatment of cervical cancer - PMC
Journal
Scientific reports
MicroRNA-215-5p inhibits the proliferation of keratinocytes and alleviates psoriasis-like inflammation by negatively regulating DYRK1A and its downstream signalling pathways
Journal
Experimental dermatology
Integrating Network Pharmacology and Experimental Verification to Explore the Mechanism of Effect of Zuojin Pills in Pancreatic Cancer Treatment
Journal
Drug Des Devel Ther
Downregulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR‐455‐5p
Journal
Journal Of Gene Medicine
Hyperforin promotes post-stroke functional recovery through interleukin (IL) 17A-mediated angiogenesis
Gefitinib represses JAK-STAT signaling activated by CRTC1-MAML2 fusion in mucoepidermoid carcinoma cells
Journal
Current cancer drug targets
Hypoxia-induced PLOD2 promotes clear cell renal cell carcinoma progression via modulating EGFR-dependent AKT pathway activation - PMC
Journal
Cell death & disease
Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells
PDL-1 expression in lung carcinoma and its correlation with clinicopathological and prognostic characteristics
Journal
J Immunoassay Immunochem