Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy - PMC
Journal
Signal transduction and targeted therapy
Nicotine rebalances NAD+ homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity - PMC
Journal
Nature communications
Tumor Cell "Slimming" Regulates Tumor Progression through PLCL1/UCP1-Mediated Lipid Browning.
Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice - PMC
Journal
Nature communications
Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1/Lipin1 axis in an aging-related sarcopenia model
Journal
The Journal of clinical investigation
Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α
Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production
Mitochondrial damage are involved in Aflatoxin B1-induced testicular damage and spermatogenesis disorder in mice
Journal
The Science of the Total Environment
Selenium deficiency exacerbated Bisphenol A-induced intestinal toxicity in chickens: Apoptosis and cell cycle arrest mediated by ROS/P53
Journal
The Science of the total environment
Medioresinol as a novel PGC-1 activator prevents pyroptosis of endothelial cells in ischemic stroke through PPAR-GOT1 axis
Ginsenoside Rh1, a novel casein kinase II subunit alpha (CK2) inhibitor, retards metastasis via disrupting HHEX/CCL20 signaling cascade involved in tumor
Journal
Pharmacological research
Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy
Journal
Pharmacological research
Silver nanoparticles modulate mitochondrial dynamics and biogenesis in HepG2 cells
Journal
Environmental pollution (Barking, Essex : 1987)
PGC-1 loss promotes mitochondrial protein lactylation in acetaminophen-induced liver injury via the LDHB-lactate axis
Journal
Pharmacological research
TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
NNTinduced tumor cell slimming reverses the procarcinogenesis effect of HIF2a in tumors
Targeting antioxidant factor Nrf2 by raffinose ameliorates lipid dysmetabolism-induced pyroptosis, inflammation and fibrosis in NAFLD
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
LncRNAH19 improves insulin resistance in skeletal muscle by regulating heterogeneous nuclear ribonucleoprotein A1
Journal
Cell Commun Signal
Dendrobium officinale regulate lipid metabolism in diabetic mouse liver via PPAR-RXR signaling pathway: Evidence from an integrated multi-omics analysis
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Pyrroloquinoline quinone promotes human mesenchymal stem cell-derived mitochondria to improve premature ovarian insufficiency in mice through the
Journal
Stem cell research & therapy
Isorhamnetin alleviates cisplatin-induced acute kidney injury via enhancing fatty acid oxidation
Journal
Free radical biology & medicine
Resveratrol alleviates lipopolysaccharide-induced liver injury by inducing SIRT1/P62-mediated mitophagy in gibel carp (Carassius gibelio) - PMC
Journal
Frontiers in immunology
Heat Shock Protein 22 Attenuates Nerve Injury-induced Neuropathic Pain Via Improving Mitochondrial Biogenesis and Reducing Oxidative Stress Mediated By Spinal
Journal
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
Resveratrol attenuated oxidative stress and inflammatory and mitochondrial dysfunction induced by acute ammonia exposure in gibel carp (Carassius gibelio)
Journal
Ecotoxicology and environmental safety
Puerarin prevents cadmium-induced mitochondrial fission in AML-12 cells via Sirt1-dependent pathway
Journal
Ecotoxicology and environmental safety
SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of 4-butyl-polyhydroxybenzophenone compounds against NAFLD
Journal
European journal of medicinal chemistry
Early derangement of axonal mitochondria occurs in a mouse model of progressive but not relapsing-remitting multiple sclerosis
Journal
Neurobiology of disease
Sesamol Alleviates Obesity-Related Hepatic Steatosis via Activating Hepatic PKA Pathway
SIRT1 activation by SRT1720 attenuates bone cancer pain via preventing Drp1-mediated mitochondrial fission.
Journal
Biochimica et biophysica acta. Molecular basis of disease
MitoQ protects dopaminergic neurons in a 6-OHDA induced PD model by enhancing Mfn2-dependent mitochondrial fusion via activation of PGC-1α
Journal
Biochimica et biophysica acta
PGC-1α Regulates Cell Proliferation, Migration, and Invasion by Modulating Leucyl-tRNA Synthetase 1 Expression in Human Colorectal Cancer Cells - PMC
Lycopene attenuates di(2-ethylhexyl) phthalate-induced mitophagy in spleen by regulating the sirtuin3-mediated pathway
Ameliorative effects of resveratrol against cadmium-induced nephrotoxicity via modulating nuclear xenobiotic receptor response and PINK1/Parkin-mediated Mitophagy
Knockdown of insulin-like growth factor 2 gene disrupts mitochondrial functions in the liver
Resveratrol inhibits the formation and accumulation of lipid droplets through AdipoQ signal pathway and lipid metabolism lncRNAs
Journal
The Journal of nutritional biochemistry
Studying Antifatigue Mechanism of Tyr-Pro-Leu-Pro in Exercise Mice Using Label-Free Proteomics
Journal
Journal of agricultural and food chemistry
Species
Mus musculus,Other
Whitening of brown adipose tissue inhibits osteogenic differentiation via secretion of S100A8/A9 - PMC
Activation of G-protein-coupled receptor 39 reduces neuropathic pain in a rat model
Journal
Neural regeneration research
Formononetin Attenuates Renal Tubular Injury and Mitochondrial Damage in Diabetic Nephropathy Partly via Regulating Sirt1/PGC-1 Pathway
Journal
Frontiers in pharmacology
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease
Journal
Frontiers in pharmacology
Cerebrolysin Ameliorates Focal Cerebral Ischemia Injury Through Neuroinflammatory Inhibition via CREB/PGC-1α Pathway.
Journal
Frontiers in Pharmacology
Berberine Ameliorates High Glucose-Induced Cardiomyocyte Injury via AMPK Signaling Activation to Stimulate Mitochondrial Biogenesis and Restore Autophagic Flux.
Journal
Frontiers in Pharmacology
Multi-Omics Integration Analysis Identifies Lipid Disorder of a Non-Alcoholic Fatty Liver Disease (NAFLD) Mouse Model Improved by Zexie-Baizhu Decoction - PMC
Journal
Frontiers in pharmacology
PGC-1 alleviates mitochondrial dysfunction via TFEB-mediated autophagy in cisplatin-induced acute kidney injury
Cerasus humilis Cherry Polyphenol Reduces High-Fat Diet-Induced Obesity in C57BL/6 Mice by Mitigating Fat Deposition, Inflammation, and Oxidation
Journal
Journal of Agricultural and Food Chemistry
A Combination of Capsaicin and Capsiate Induces Browning in 3T3-L1 White Adipocytes via Activation of the PPARγ/ β3-AR Signaling Pathways.
Journal
Journal of agricultural and food chemistry
PGC1α promotes cisplatin resistance in human ovarian carcinoma cells through upregulation of mitochondrial biogenesis
Journal
International Journal of oncology
CYP2E1-dependent upregulation of SIRT7 is response to alcohol mediated metastasis in hepatocellular carcinoma
Journal
Cancer gene therapy
Sirtuin 6 supra‐physiological overexpression in hypothalamic pro‐opiomelanocortin neurons promotes obesity via the hypothalamus‐adipose axis
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
EGCG alleviates heat-stress-induced fat deposition by targeting HSP70 through activation of AMPK-SIRT1-PGC-1 in porcine subcutaneous preadipocytes
Journal
Biochemical pharmacology
Sorafenib reduces the production of epoxyeicosatrienoic acids and leads to cardiac injury by inhibiting CYP2J in rats
Journal
Biochemical pharmacology
USP18 Stabilized FTO Protein to Activate Mitophagy in Ischemic Stroke Through Repressing m6A Modification of SIRT6
Journal
Molecular neurobiology
A novel mutation in human EMD gene and mitochondrial dysfunction in emerin knockdown cardiomyocytes
Journal
Journal of cellular and molecular medicine
Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission
IL-33 promotes pancreatic -cell survival and insulin secretion under diabetogenic conditions through PPAR
Journal
European journal of pharmacology
HDAC1 inhibits beige adipocyte-mediated thermogenesis through histone crotonylation of Pgc1a/Ucp1
Journal
Cellular signalling
Acupuncture modulates the AMPK/PGC-1 signaling pathway to facilitate mitochondrial biogenesis and neural recovery in ischemic stroke rats - PMC
Journal
Frontiers in molecular neuroscience
Ginsenoside Rb1 Protects Against Diabetic Cardiomyopathy by Regulating the Adipocytokine Pathway
Journal
Journal of inflammation research
Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats - PMC
Deoxyarbutin attenuates severe acute pancreatitis via the HtrA2/PGC-1α pathway
Journal
Free radical research
MALAT1 Up-Regulator Polydatin Protects Brain Microvascular Integrity and Ameliorates Stroke Through C/EBPβ/MALAT1/CREB/PGC-1α/PPARγ Pathway.
Journal
Cellular and molecular neurobiology
The PGC-1α Activator ZLN005 Ameliorates Ischemia-Induced Neuronal Injury In Vitro and In Vivo
Journal
Cellular and molecular neurobiology
Effects of manganese on microglia M1/M2 polarization and SIRT1-mediated transcription of STAT3-dependent genes in mouse
Plasmodium infection suppresses colon cancer growth by inhibiting proliferation and promoting apoptosis associated with disrupting mitochondrial biogenesis and mitophagy in mice - PMC
Journal
Parasites & vectors
Moderate intensity continuous versus high intensity interval training: Metabolic responses of slow and fast skeletal muscles in rat - PMC
Lactobacillus plantarum dy‐1 fermented barley extraction activates white adipocyte browning in high‐fat diet‐induced obese rats
Journal
Journal of food biochemistry
Targeting PHB2 mediated mitophagy alleviates non-esterified fatty acid-induced mitochondrial dysfunction in bovine mammary epithelial cells
Journal
Journal of dairy science
Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism
Journal
Molecular Medicine Reports
Astragalus polysaccharide mitigates transport stress-induced hepatic metabolic stress via improving hepatic glucolipid metabolism in chicks
Journal
Journal of animal science
Effects of exercise and dietary intervention on muscle, adipose tissue, and blood IRISIN levels in obese male mice and their relationship with the beigeization of white adipose tissue
Journal
Endocrine connections
Transfer of massive mitochondria from astrocytes reduce propofol neurotoxicity
Journal
Neuroscience letters
Chrysophanol Suppresses Cell Growth via mTOR/PPAR-α Regulation and ROS Accumulation in Cultured Human Tongue Squamous Carcinoma SAS Cells - PMC
Journal
Current issues in molecular biology
The worsening of skeletal muscle atrophy induced by immobilization at the early stage of remobilization correlates with BNIP3-dependent mitophagy - PMC
Journal
BMC musculoskeletal disorders
Glucocorticoid intermittence coordinates rescue of energy and mass in aging-related sarcopenia through the myocyte-autonomous PGC1alpha-Lipin1 transactivation - PMC
Journal
bioRxiv : the preprint server for biology
Tubular β-catenin alleviates mitochondrial dysfunction and cell death in acute kidney injury - PMC
Journal
Cell death & disease