Astaxanthine attenuates cisplatin ototoxicity in vitro and protects against cisplatin-induced hearing loss in vivo
Journal
Acta pharmaceutica Sinica. B
A novel marine-derived anti-acute kidney injury agent targeting peroxiredoxin 1 and its nanodelivery strategy based on ADME optimization
Journal
Acta pharmaceutica Sinica. B
TIGAR alleviates oxidative stress in brain with extended ischemia via a pentose phosphate pathway-independent manner
EP1 activation inhibits doxorubicin-cardiomyocyte ferroptosis via Nrf2 - PMC
Species
Homo sapiens, Mus musculus, Rattus norvegicus
Apigenin targets fetuin-A to ameliorate obesity-induced insulin resistance - PMC
Journal
International journal of biological sciences
Apigenin targets fetuin-A to ameliorate obesity-induced insulin resistance - PMC
Journal
International journal of biological sciences
Identification of molecular subtypes based on PANoptosis-related genes and construction of a signature for predicting the prognosis and response to immunotherapy response in hepatocellular carcinoma - PMC
Journal
Frontiers in immunology
miR-200a attenuated oxidative stress, inflammation, and apoptosis in dextran sulfate sodium-induced colitis through activation of Nrf2 - PMC
Journal
Frontiers in immunology
Fucoidan from Apostichopus japonicus ameliorates alcoholic liver disease by regulating gut-liver axis homeostasis
Journal
International journal of biological macromolecules
Induction of monoamine oxidase A-mediated oxidative stress and impairment of NRF2-antioxidant defence response by polyphenol-rich fraction of Bergenia ligulata sensitizes prostate cancer cells in vitro and in vivo
Journal
Free Radic Biol Med
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion
Journal
Free Radic Biol Med
Study of anti-fatigue activity of polysaccharide from fruiting bodies of Armillaria gallica
Journal
International journal of biological macromolecules
Study of anti-fatigue activity of polysaccharide from fruiting bodies of Armillaria gallica
Journal
International journal of biological macromolecules
Tolerance Assessment of Atractylodes macrocephala Polysaccharide in the Diet of Largemouth Bass (Micropterus salmoides) - PMC
Journal
Antioxidants (Basel, Switzerland)
Evaluation of lung protection of Sanghuangporus sanghuang through TLR4/NF-B/MAPK, keap1/Nrf2/HO-1, CaMKK/AMPK/Sirt1, and TGF-/SMAD3
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Electrical Pulse Stimulation Protects C2C12 Myotubes against Hydrogen Peroxide-Induced Cytotoxicity via Nrf2/Antioxidant Pathway - PMC
Journal
Antioxidants (Basel, Switzerland)
Aloin alleviates pathological cardiac hypertrophy via modulation of the oxidative and fibrotic response
Sulforaphane Combined with Vitamin D Induces Cytotoxicity Mediated by Oxidative Stress, DNA Damage, Autophagy, and JNK/MAPK Pathway Modulation in …
Hericium coralloides Ameliorates Alzheimers Disease Pathologies and Cognitive Disorders by Activating Nrf2 Signaling and Regulating Gut Microbiota - PMC
Puerariae lobatae Radix Alleviates Pre-Eclampsia by Remodeling Gut Microbiota and Protecting the Gut and Placental Barriers - PMC
Lactobacillus plantarum Y44 alleviates oxidative stress by regulating gut microbiota and colonic barrier function in Balb/C mice with subcutaneous D-galactose injection
The preventive effect and underlying mechanism of Rhus chinensis Mill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice
The role of transforming growth factor-beta in retinal ganglion cells with hyperglycemia and oxidative stress
Journal
International journal of molecular sciences
Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis - PMC
Journal
International journal of molecular sciences
Farrerol Alleviates Myocardial Ischemia/Reperfusion Injury by Targeting Macrophages and NLRP3
Journal
Frontiers in pharmacology
Effects of unburned tobacco smoke on inflammatory and oxidative mediators in the rat prefrontal cortex - PMC
Journal
Frontiers in pharmacology
Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/Nrf2 signaling pathway - PMC
Journal
Frontiers in pharmacology
Essential oil from the roots of Paeonia lactiflora pall. has protective effect against corticosterone-induced depression in mice via modulation of PI3K/Akt signaling pathway - PMC
Journal
Frontiers in pharmacology
Lycopene prevents DEHP-induced Leydig cell damage with the Nrf2 antioxidant signaling pathway in mice
Journal
Journal of agricultural and food chemistry
Astragaloside IV regulates the ferroptosis signaling pathway via the Nrf2/SLC7A11/GPX4 axis to inhibit PM2. 5-mediated lung injury in mice
Journal
International immunopharmacology
Melatonin suppresses ferroptosis via activation of the Nrf2/HO-1 signaling pathway in the mouse model of sepsis-induced acute kidney injury
Journal
International immunopharmacology
Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan
Journal
Molecular Neurobiology
Etomidate Improves the Antidepressant Effect of Electroconvulsive Therapy by Suppressing Hippocampal Neuronal Ferroptosis via Upregulating BDNF/Nrf2
Journal
Molecular neurobiology
Transcriptional Up-Regulation of FBXW7 by KCa1.1 K+ Channel Inhibition through the Nrf2 Signaling Pathway in Human Prostate Cancer LNCaP Cell Spheroid Model - PMC
Journal
International journal of molecular sciences
FGF10 protects against particulate matter-induced lung injury by inhibiting ferroptosis via Nrf2-dependent signaling
Journal
International immunopharmacology
4-octyl itaconate alleviates cisplatin-induced ferroptosis possibly via activating the NRF2/HO-1 signalling pathway - PMC
Journal
Journal of cellular and molecular medicine
BaZiBuShen alleviates cognitive deficits and regulates Sirt6/NRF2/HO-1 and Sirt6/P53-PGC-1α-TERT signaling pathways in aging mice
Inhibition of MALT1 reduces ferroptosis in rat hearts following ischemia/reperfusion via enhancing the Nrf2/SLC7A11 pathway
Journal
European journal of pharmacology
Kinsenoside mitigates myocardial ischemia/reperfusion-induced ferroptosis via activation of the Akt/Nrf2/HO-1 pathway
Journal
European journal of pharmacology
Species
Mus musculus, Rattus norvegicus
Rhus chinensis Mill. fruits alleviate liver injury induced by isoniazid and rifampicin through regulating oxidative stress, apoptosis, and bile acid transport
Journal
Journal of ethnopharmacology
Paeoniflorin attenuates particulate matter-induced acute lung injury by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis through activation of
Journal
Chemico-biological interactions
Acute and long-term effects of cannabinoids on hypertension and kidney injury
Journal
Scientific reports
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis - PMC
Journal
Drug design, development and therapy
Nobiletin alleviates cisplatin-induced ototoxicity via activating autophagy and inhibiting NRF2/GPX4-mediated ferroptosis
Journal
Scientific reports
Saikosaponin a attenuates lead-induced kidney injury through activating Nrf2 signaling pathway
Journal
Comparative Biochemistry And Physiology C-Toxicology & Pharmacology
β-Asarone Exerts Antioxidative Effects on H 2 O 2-Stimulated PC12 Cells by Activating Nrf2/HO-1 Pathway
Anwulignan Ameliorates the Intestinal Ischemia/Reperfusion
Journal
The Journal of pharmacology and experimental therapeutics
Loganin Attenuates Septic Acute Renal Injury with the Participation of AKT and Nrf2/HO-1 Signaling Pathways
Journal
Drug Des Devel Ther
Propofol induces proliferation partially via downregulation of p53 protein and promotes migration via activation of the Nrf2 pathway in human breast cancer cell line MDA-MB-231
Athelia rolfsii Exopolysaccharide Protection Against Kidney Injury in Lead-Exposed Mice via Nrf2 Signaling Pathway
Journal
Biological trace element research
3-methyladenine ameliorates acute lung injury by inhibiting oxidative damage and apoptosis - PMC
NIX protein enhances antioxidant capacity of and reduces the apoptosis induced by HSP90 inhibitor luminespib/NVP-AUY922 in PC12 cells
Journal
Cell Stress Chaperones
Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis
Journal
Toxicology and Applied Pharmacology
Corynoline ameliorates dextran sulfate sodium-induced colitis in mice by modulating Nrf2/NF-κB pathway
Journal
Immunopharmacology and immunotoxicology
Effect of oligonol, a lychee-derived polyphenol, on skeletal muscle in ovariectomized rats by regulating body composition, protein turnover, and mitochondrial quality signaling
Journal
Food science & nutrition
Long Non-Coding RNA PVT1 Regulates the Resistance of the Breast Cancer Cell Line MDA-MB-231 to Doxorubicin via Nrf2
Journal
Technol Cancer Res Treat
Emodin Alleviates Arthritis Pain through Reducing Spinal Inflammation and Oxidative Stress
Astragaloside IV Inhibits NLRP3 Inflammasome-Mediated Pyroptosis via Activation of Nrf-2/HO-1 Signaling Pathway and Protects against Doxorubicin
Journal
Frontiers in bioscience (Landmark edition)
Alleviating effect of lycorine on CFA-induced arthritic pain via inhibition of spinal inflammation and oxidative stress - PMC
Journal
Experimental and therapeutic medicine
Canagliflozin ameliorates high glucose-induced apoptosis in NRK-52E cells via inhibiting oxidative stress and activating AMPK/mTOR-mediated autophagy
Journal
Molecular biology reports
The ethanol leaf extract of Andrographis paniculata blunts acute renal failure in cisplatin-induced injury in rats through inhibition of Kim-1 and upregulation of Nrf2 pathway
Journal
Journal of basic and clinical physiology and pharmacology