Licochalcone A plays dual antiviral roles by inhibiting RSV and protecting against host damage
Journal
Journal of medical virology
Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma.
Journal
Journal of Experimental Medicine
Astaxanthine attenuates cisplatin ototoxicity in vitro and protects against cisplatin-induced hearing loss in vivo
Journal
Acta pharmaceutica Sinica. B
Solid fuel derived PM2. 5 induced oxidative stress and according cytotoxicity in A549 cells: The evidence and potential neutralization by green tea
Journal
Environment international
Construction of Phlorotannin-Based Nanoparticles for Alleviating Acute Liver Injury
Journal
ACS applied materials & interfaces
Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1
Journal
British Journal Of Pharmacology
Phenolic constituents, antioxidant activity and neuroprotective effects of ethanol extracts of fruits, leaves and flower buds from Vaccinium dunalianum Wight
Species
Vaccinium dunalianum
PL201, a Reported Rhamnoside Against Alzheimer's Disease Pathology, Alleviates Neuroinflammation and Stimulates Nrf2 Signaling
Journal
Frontiers in Immunology
miR-200a attenuated oxidative stress, inflammation, and apoptosis in dextran sulfate sodium-induced colitis through activation of Nrf2 - PMC
Journal
Frontiers in immunology
The crosstalk between DRP1-dependent mitochondrial fission and oxidative stress triggers hepatocyte apoptosis induced by silver nanoparticles
Iron deficiency exacerbates cisplatin-or rhabdomyolysis-induced acute kidney injury through promoting iron-catalyzed oxidative damage
Journal
Free Radic Biol Med
Connexin43 regulates high glucose-induced expression of fibronectin, ICAM-1 and TGF-β1 via Nrf2/ARE pathway in glomerular mesangial cells
Journal
Free Radical Biology and Medicine
Echinacea purpurea polysaccharide prepared by fractional precipitation prevents alcoholic liver injury in mice by protecting the intestinal barrier and regulating liver-related pathways
Journal
Int J Biol Macromol
Oyster (Crassostrea gigas) ferritin relieves lead-induced liver oxidative damage via regulating the mitophagy
Journal
International journal of biological macromolecules
Fucoidan-functionalized gelatin methacryloyl microspheres ameliorate intervertebral disc degeneration by restoring redox and matrix homeostasis of nucleus
Journal
International journal of biological macromolecules
Effect fraction of Bletilla striata (Thunb.) Reichb. f. alleviates LPS-induced acute lung injury by inhibiting p47phox/NOX2 and promoting the Nrf2/HO-1 signaling
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Empagliflozin-Enhanced Antioxidant Defense Attenuates Lipotoxicity and Protects Hepatocytes by Promoting FoxO3a- and Nrf2-Mediated Nuclear Translocation via the CAMKK2/AMPK Pathway
Journal
Antioxidants (Basel, Switzerland)
Hyperoside and Quercitrin in Houttuynia cordata Extract Attenuate UVB-Induced Human Keratinocyte Cell Damage and Oxidative Stress via Modulation of MAPKs and Akt Signaling Pathway
Journal
Antioxidants (Basel, Switzerland)
Luteolin Alleviates AflatoxinB 1-Induced Apoptosis and Oxidative Stress in the Liver of Mice through Activation of Nrf2 Signaling Pathway
Journal
Antioxidants (Basel)
DHPA Protects SH-SY5Y Cells from Oxidative Stress-Induced Apoptosis via Mitochondria Apoptosis and the Keap1/Nrf2/HO-1 Signaling Pathway - PMC
Journal
Antioxidants (Basel, Switzerland)
Two sesquiterpene aminoquinones protect against oxidative injury in HaCaT keratinocytes via activation of AMPKα/ERK-Nrf2/ARE/HO-1 signaling
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ephedra herb reduces adriamycin-induced testicular toxicity by upregulating the gonadotropin-releasing hormone signalling pathway
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Silibinin Ameliorates Formaldehyde-Induced Cognitive Impairment by Inhibiting Oxidative Stress - PMC
Journal
Oxidative medicine and cellular longevity
NS1619 Alleviate Brain-Derived Extracellular Vesicle-Induced Brain Injury by Regulating BKca Channel and Nrf2/HO-1/NF-ĸB Pathway - PMC
Journal
Oxidative medicine and cellular longevity
In vitro evaluation of nanoplastics using human lung epithelial cells, microarray analysis and co-culture model
Journal
Ecotoxicol Environ Saf
Biochanin A alleviates unilateral ureteral obstruction-induced renal interstitial fibrosis and inflammation by inhibiting the TGF-1/Smad2/3 and NF-kB/NLRP3 signaling axis in mice
Lactiplantibacillus plantarum GL001 alleviates jejunal oxidative damage induced by intestinal ischemia-reperfusion injury by influencing jejunal tissue metabolism
Role of diets and exercise in ameliorating obesity-related hepatic steatosis: Insights at the microRNA-dependent thyroid hormone synthesis and action
Oat Peptides Alleviate Dextran Sulfate Sodium Salt-Induced Colitis by Maintaining the Intestinal Barrier and Modulating the Keap1-Nrf2 Axis - PMC
Chinese Sumac Fruits (Rhus chinesis Mill.) Alleviate Type 2 Diabetes in C57BL/6 Mice through Repairing Islet Cell Functions, Regulating IRS-1/PI3K/AKT Pathways and Promoting the Entry of Nrf2 into the Nucleus - PMC
Stingless Bee (Heterotrigona Itama) Honey and Its Phenolic-Rich Extract Ameliorate Oxidant-Antioxidant Balance via KEAP1-NRF2 Signalling Pathway - PMC
Puerariae lobatae Radix Alleviates Pre-Eclampsia by Remodeling Gut Microbiota and Protecting the Gut and Placental Barriers - PMC
Sarmentosin promotes USP17 and regulates Nrf2-mediated mitophagy and cellular oxidative stress to alleviate APAP-induced acute liver failure
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Total terpenoids of Inula japonica activated the Nrf2 receptor to alleviate the inflammation and oxidative stress in LPS-induced acute lung injury
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Neuroprotective effects of aucubin on hydrogen peroxide-induced toxicity in human neuroblastoma SH-SY5Y cells via the Nrf2/HO-1 pathway
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
4-Octyl Itaconate Prevents Free Fatty Acid-Induced Lipid Metabolism Disorder through Activating Nrf2-AMPK Signaling Pathway in Hepatocytes
Journal
Oxidative medicine and cellular longevity
Low Molecular Weight Fucoidan Inhibits Pulmonary Fibrosis In Vivo and In Vitro via Antioxidant Activity
Journal
Oxidative medicine and cellular longevity
Saccharomyces boulardii Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Regulating NF- κ B and Nrf2 Signaling Pathways
Journal
Oxid Med Cell Longev
F. prausnitzii-derived extracellular vesicles attenuate experimental colitis by regulating intestinal homeostasis in mice - PMC
Journal
Microbial cell factories
Lactobacillus plantarum Y44 alleviates oxidative stress by regulating gut microbiota and colonic barrier function in Balb/C mice with subcutaneous D-galactose injection
(-)-Epicatechin gallate blocked cellular foam formation in atherosclerosis by modulating CD36 expression in vitro and in vivo
The preventive effect and underlying mechanism of Rhus chinensis Mill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice
Gastroprotective effect and mechanisms of Chinese sumac fruits (Rhus chinensis Mill.) on ethanol-induced gastric ulcers in mice
Replacing dietary sodium selenite with biogenic selenium nanoparticles improves the growth performance and gut health of early-weaned piglets
Anti-Inflammatory and Anti-Oxidative Activity of Indole-3-Acetic Acid Involves Induction of HO-1 and Neutralization of Free Radicals in RAW264.7 Cells
Journal
International Journal of Molecular Sciences
Empagliflozin Attenuates Vascular Calcification in Mice with Chronic Kidney Disease by Regulating the NFR2/HO-1 Anti-Inflammatory Pathway through AMPK Activation - PMC
Journal
International journal of molecular sciences
Propolis Ethanolic Extract Attenuates D-gal-induced C2C12 Cell Injury by Modulating Nrf2/HO-1 and p38/p53 Signaling Pathways
Journal
International journal of molecular sciences
Diclofenac Sensitizes Signet Ring Cell Gastric Carcinoma Cells to Cisplatin by Activating Autophagy and Inhibition of Survival Signal Pathways - PMC
Journal
International journal of molecular sciences
Astaxanthin Promotes Nrf2/ARE Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs
Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis
Journal
Frontiers in cell and developmental biology
Oral administration of live combined Bacillus subtilis and Enterococcus faecium alleviates colonic oxidative stress and inflammation in osteoarthritic rats by improving fecal microbiome metabolism and enhancing the colonic barrier - PMC
Journal
Frontiers in microbiology
Network pharmacology and experimental validation to elucidate the pharmacological mechanisms of Bushen Huashi decoction against kidney stones - PMC
Journal
Frontiers in endocrinology
Activation of p62-NRF2 Axis Protects against Doxorubicin-Induced Ferroptosis in Cardiomyocytes: A Novel Role and Molecular Mechanism of Resveratrol
Journal
The American journal of Chinese medicine
Burdock Fructooligosaccharide Attenuates High Glucose-Induced Apoptosis and Oxidative Stress Injury in Renal Tubular Epithelial Cells.
Journal
Frontiers in pharmacology
Involvement of CYP2E1 in the Course of Brain Edema Induced by Subacute Poisoning With 1,2-Dichloroethane in Mice.
Journal
Frontiers in Pharmacology
Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1
Journal
Frontiers in pharmacology
Rev-erbα agonist SR9009 protects against cerebral ischemic injury through mechanisms involving Nrf2 pathway - PMC
Journal
Frontiers in pharmacology
Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/Nrf2 signaling pathway - PMC
Journal
Frontiers in pharmacology
Lycopene prevents carcinogen-induced cutaneous tumor by enhancing activation of the Nrf2 pathway through p62-triggered autophagic Keap1 degradation.
Role of PDK4 in insulin signaling pathway in periadrenal adipose tissue of pheochromocytoma patients
Journal
Endocrine-related cancer
Torularhodin from Sporidiobolus pararoseus Attenuates d-galactose/AlCl 3 -Induced Cognitive Impairment, Oxidative Stress, and Neuroinflammation via the Nrf2/NF-κB Pathway
Journal
Journal of agricultural and food chemistry
Shortening of HO1 3′ UTRs by Alternative Polyadenylation Suppresses Adipogenesis in 3T3-L1
Astaxanthin Protects against Alcoholic Liver Injury via Regulating Mitochondrial Redox Balance and Calcium Homeostasis
Journal
Journal of agricultural and food chemistry
Rosmarinic Acid Inhibits Platelet Aggregation and Neointimal Hyperplasia In Vivo and Vascular Smooth Muscle Cell Dedifferentiation, Proliferation, and Migration In
Journal
Journal of agricultural and food chemistry
Lycopene prevents DEHP-induced Leydig cell damage with the Nrf2 antioxidant signaling pathway in mice
Journal
Journal of agricultural and food chemistry
Intranasal administration of β‐1, 3‐galactosyltransferase 2 confers neuroprotection against ischemic stroke by likely inhibiting oxidative stress and NLRP3 …
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Remote ischemic postconditioning protects against renal ischemia/reperfusion injury by activation of T-LAK-cell-originated protein kinase (TOPK)/PTEN/Akt signaling pathway mediated anti-oxidation and anti-inflammation
Journal
International immunopharmacology
Resveratrol alleviates oxidative stress caused by Streptococcus uberis infection via activating the Nrf2 signaling pathway
Journal
Int Immunopharmacol
Annexin A5 ameliorates traumatic brain injury-induced neuroinflammation and neuronal ferroptosis by modulating the NF-B/HMGB1 and Nrf2/HO-1
Journal
International immunopharmacology
pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway
Journal
International immunopharmacology
Astragaloside IV supplementation attenuates cognitive impairment by inhibiting neuroinflammation and oxidative stress in type 2 diabetic mice - PMC
Journal
Frontiers in aging neuroscience
The Mitochondrial-Derived Peptide (MOTS-c) Interacted with Nrf2 to Defend the Antioxidant System to Protect Dopaminergic Neurons Against Rotenone Exposure
Journal
Molecular neurobiology
GAPDH Is a Novel Ferroptosis-Related Marker and Correlates with Immune Microenvironment in Lung Adenocarcinoma - PMC
GAPDH Is a Novel Ferroptosis-Related Marker and Correlates with Immune Microenvironment in Lung Adenocarcinoma - PMC
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway
Lycopene ameliorates atrazine-induced spatial learning and memory impairments by inhibiting ferroptosis in the hippocampus of mice
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury
Overexpression of c-Jun inhibits erastin-induced ferroptosis in Schwann cells and promotes repair of facial nerve function
Journal
Journal of cellular and molecular medicine
A novel biscoumarin compound ameliorates cerebral ischemia reperfusion-induced mitochondrial oxidative injury via Nrf2/Keap1/ARE signaling
Chinese sumac (Rhus chinensis Mill.) fruits alleviate indomethacin-induced gastric ulcer in mice by improving oxidative stress, inflammation and apoptosis
Diabetes blocks the cardioprotective effects of sevoflurane postconditioning by impairing Nrf2/Brg1/HO-1 signaling
Journal
European Journal of Pharmacology
Zanthoxylum bungeanum amides ameliorates nonalcoholic fatty liver via regulating gut microbiota and activating AMPK/Nrf2 signaling
Journal
Journal of ethnopharmacology
Interpretation of the anti-influenza active ingredients and potential mechanisms of Ge Gen Decoction based on spectrum-effect relationships and network analysis
Journal
Journal of ethnopharmacology
Rhus chinensis Mill. fruits alleviate liver injury induced by isoniazid and rifampicin through regulating oxidative stress, apoptosis, and bile acid transport
Journal
Journal of ethnopharmacology
Oral administration of ellagic acid mitigates perioperative neurocognitive disorders, hippocampal oxidative stress, and neuroinflammation in aged mice by restoring IGF-1 signaling - PMC
Journal
Scientific reports
Cepharanthine Exerts Antioxidant and Anti-Inflammatory Effects in Lipopolysaccharide (LPS)-Induced Macrophages and DSS-Induced Colitis Mice - PMC
Journal
Molecules (Basel, Switzerland)
Recombinant Human Annexin A5 Alleviated Traumatic-Brain-Injury Induced Intestinal Injury by Regulating the Nrf2/HO-1/HMGB1 Pathway - PMC
Journal
Molecules (Basel, Switzerland)
Kartogenin-enhanced dynamic hydrogel ameliorates intervertebral disc degeneration via restoration of local redox homeostasis - PMC
Journal
Journal of orthopaedic translation
Inula japonica ameliorated the inflammation and oxidative stress in LPS-induced acute lung injury through the MAPK/NF-κB and Keap1/Nrf2 signalling pathways
Journal
The Journal of pharmacy and pharmacology
Study on the attenuated effect of Ginkgolide B on ferroptosis in high fat diet induced nonalcoholic fatty liver disease
NLRP3 inflammasome inhibition attenuates subacute neurotoxicity induced by acrylamide in vitro and in vivo
Maternal exposure to PM2. 5 decreases ovarian reserve in neonatal offspring mice through activating PI3K/AKT/FoxO3a pathway and ROS-dependent NF-κB pathway
Oridonin Inhibits Mycobacterium marinum Infection-Induced Oxidative Stress In Vitro and In Vivo - PMC
Journal
Pathogens (Basel, Switzerland)
Saikosaponin a attenuates lead-induced kidney injury through activating Nrf2 signaling pathway
Journal
Comparative Biochemistry And Physiology C-Toxicology & Pharmacology
Syringaldehyde Exhibits Antibacterial and Antioxidant Activities against Mycobacterium marinum Infection - PMC
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis - PMC
Journal
Journal of immunology research
β-Asarone Exerts Antioxidative Effects on H 2 O 2-Stimulated PC12 Cells by Activating Nrf2/HO-1 Pathway
Insufficient autophagy enables the nuclear factor erythroid 2-related factor 2 (NRF2) to promote ferroptosis in morphine-treated SH-SY5Y cells
Journal
Psychopharmacology
Anwulignan Ameliorates the Intestinal Ischemia/Reperfusion
Journal
The Journal of pharmacology and experimental therapeutics
Protective Effect of Anwulignan on Gastric Injury Induced by Indomethacin in Mice
Journal
The Journal of pharmacology and experimental therapeutics
Loganin Attenuates Septic Acute Renal Injury with the Participation of AKT and Nrf2/HO-1 Signaling Pathways
Journal
Drug Des Devel Ther
Puerarin ameliorates metabolic dysfunction-associated fatty liver disease by inhibiting ferroptosis and inflammation - PMC
Journal
Lipids in health and disease
Ferroptosis mediated DSS-induced ulcerative colitis associated with Nrf2/HO-1 signaling pathway
Dehydroepiandrosterone attenuates LPS-induced inflammatory responses via activation of Nrf2 in RAW264. 7 macrophages
Journal
Molecular immunology
Screening and verification of proteins that interact with HSPC238
Leucine protects bovine intestinal epithelial cells from hydrogen peroxide-induced apoptosis by alleviating oxidative damage
Journal
Journal of the science of food and agriculture
Mdivi-1 alleviates cardiac fibrosis post myocardial infarction at infarcted border zone, possibly via inhibition of Drp1-Activated mitochondrial fission and oxidative stress
Journal
Archives of biochemistry and biophysics
Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks
Journal
BIOLOGICAL TRACE ELEMENT RESEARCH
Danggui-Buxue decoction alleviated vascular senescence in mice exposed to chronic intermittent hypoxia through activating the Nrf2/HO-1 pathway - PMC
Journal
Pharmaceutical biology
Triptolide attenuates cardiac remodeling by inhibiting pyroptosis and EndMT via modulating USP14/Keap1/Nrf2 pathway - PMC
Network pharmacology and in vivo studies reveal the neuroprotective effects of paeoniflorin on Alzheimer's disease - PMC
Corynoline ameliorates dextran sulfate sodium-induced colitis in mice by modulating Nrf2/NF-κB pathway
Journal
Immunopharmacology and immunotoxicology
Chronic intermittent hypoxia aggravated diabetic cardiomyopathy through LKB1/AMPK/Nrf2 signaling pathway - PMC
The role of CUL3 in cerebral ischemia-reperfusion injury
Genistein mitigates oxidative stress and inflammation by regulating Nrf2/HO-1 and NF-κB signaling pathways in hypoxic-ischemic brain damage in neonatal mice
Journal
Annals of translational medicine
Increased oxidative stress, inflammation and fibrosis in perirenal adipose tissue of patients with cortisol-producing adenoma.
Physiological functions of Ferroportin in the regulation of renal iron recycling and ischemic acute kidney injury.
Journal
American Journal of Physiology. Renal Physiology
Porous SiO2‐coated ultrasmall selenium particles nanospheres attenuate cerulein‐induce acute pancreatitis in mice by downregulating oxidative stress
Journal
Journal of digestive diseases
Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice
Journal
Biochemical And Biophysical Research Communications
Inhibition of heme oxygenase 1 alleviates thoracic aortic aneurysm via restoration of extracellular matrix
Journal
Biochemical and biophysical research communications
Iron overload enhances TBI-induced cardiac dysfunction by promoting ferroptosis and cardiac inflammation
Journal
Biochemical and biophysical research communications
Electroacupuncture Reduces Inflammatory Bowel Disease in Obese Mice by Activating the Nrf2/HO-1 Signaling Pathways and Repairing the Intestinal Barrier - PMC
Journal
Diabetes, metabolic syndrome and obesity : targets and therapy
Electroacupuncture Reduces Inflammatory Bowel Disease in Obese Mice by Activating the Nrf2/HO-1 Signaling Pathways and Repairing the Intestinal Barrier - PMC
Journal
Diabetes, metabolic syndrome and obesity : targets and therapy
Anwulignan alleviates d-galactose induced renal damage by regulating Nrf2/ARE signaling pathway in mice
Journal
Food Sci Biotechnol
Edaravone promotes viability of random skin flaps via activating PI3K/Akt/mTOR signalling pathway‐mediated enhancement of autophagy
Journal
International wound journal
Hydrogen Attenuates Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy by Regulating Iron Metabolism - PMC
Journal
Current issues in molecular biology
Dietary mulberry-leaf flavonoids improve the eggshell quality of aged breeder hens
Schisantherin A improves learning and memory abilities partly through regulating the Nrf2/Keap1/ARE signaling pathway in chronic fatigue mice
Protective Effects of Anwulignan against HCl/Ethanol-Induced Acute Gastric Ulcer in Mice
Journal
Evid Based Complement Alternat Med
GYY4137 protects against myocardial ischemia/reperfusion injury via activation of the PHLPP-1/Akt/Nrf2 signaling pathway in diabetic mice
Journal
Journal of Surgical Research
Monoside antagonizes triptolide-induced hepatocyte apoptosis via the anti-oxidative stress pathway
Journal
Nan fang yi ke da xue xue bao = Journal of Southern Medical University
p62/SQSTM1 protects against cisplatin-induced oxidative stress in kidneys by mediating the cross talk between autophagy and the Keap1-Nrf2 signalling pathway
Journal
Free radical research
Remote Limb Ischaemic Postconditioning Protects Against Myocardial Ischaemia/Reperfusion Injury in Mice: Activation of JAK/STAT3-Mediated Nrf2-Antioxidant Signalling
Journal
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology