CPT1A induction following epigenetic perturbation promotes MAVS palmitoylation and activation to potentiate antitumor immunity
Naked mole-rat brown fat thermogenesis is diminished during hypoxia through a rapid decrease in UCP1
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury - PMC
Journal
Nature communications
Mitochondrial Transfer Regulates Cell Fate Through Metabolic Remodeling in Osteoporosis
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Extracellular vesicles from lung tissue drive bone marrow neutrophil recruitment in inflammation
Journal
Journal of extracellular vesicles
mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
SIRT5 impairs aggregation and activation of the signaling adaptor MAVS through catalyzing lysine desuccinylation
A mitochondrial SCF‐FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease
Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption
Journal
Developmental cell
Muscle PARP1 inhibition extends lifespan through AMPK PARylation and activation in Drosophila
Journal
Proceedings of the National Academy of Sciences of the United States of America
Species
Drosophila melanogaster
Optimized allotopic expression of mitochondrial ND6 transgene restored complex I and apoptosis deficiencies caused by LHON-linked ND6 14484T>C mutation - PMC
Journal
Journal of biomedical science
Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE-/-mice - PMC
TIGAR alleviates oxidative stress in brain with extended ischemia via a pentose phosphate pathway-independent manner
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients - PMC
Journal
International journal of biological sciences
Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction
Journal
Cell chemical biology
Retrograde regulation of mitochondrial fission and epithelial to mesenchymal transition in hepatocellular carcinoma by GCN5L1
Innate sensing of picornavirus infection involves cGAS-STING-mediated antiviral responses triggered by mitochondrial DNA release
Glutathione Peroxidase 3 induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate
Journal
Journal of Translational Medicine
Gestational stress decreases postpartum mitochondrial respiration in the prefrontal cortex of female rats - PMC
Journal
Neurobiology of stress
PHB2 Alleviates Neurotoxicity of Prion Peptide PrP106-126 via PINK1/Parkin-Dependent Mitophagy - PMC
Journal
International journal of molecular sciences
Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1 - PMC
Dexmedetomidine Enhances Autophagy via α2-AR/AMPK/mTOR Pathway to Inhibit the Activation of NLRP3 Inflammasome and Subsequently Alleviates Lipopolysaccharide-Induced Acute Kidney Injury
Breviscapine remodels myocardial glucose and lipid metabolism by regulating serotonin to alleviate doxorubicin-induced cardiotoxicity - PMC
Journal
Frontiers in pharmacology
GPA peptide inhibits NLRP3 inflammasome activation to ameliorate colitis through AMPK pathway
Dexmedetomidine Alleviates Lipopolysaccharide-Induced hippocampal neuronal apoptosis via inhibiting the p38 MAPK/c-Myc/CLIC4 Signaling Pathway in Rats
Journal
Molecular neurobiology
FOXO3a-dependent up-regulation of HSP90 alleviates cisplatin-induced apoptosis by activating FUNDC1-mediated mitophagy in hypoxic osteosarcoma cells
Journal
Cellular signalling
Dimethoxytolyl propylresorcinol induces apoptosis and mitophagy in human leukemia cells through the PI3K/AKT pathway - PMC
Species
Dianella ensifolia,Homo sapiens
p120-catenin promotes innate antiviral immunity through stabilizing TBK1-IRF3 complex
Journal
Molecular immunology
Deficiency of nucleosome-destabilizing factor GLYR1 dampens spermatogenesis in mice
Journal
Molecular and cellular endocrinology
Ac-YVAD-cmk ameliorated sevoflurane-induced cognitive dysfunction and revised mitophagy impairment - PMC
Ononin alleviates DSS-induced colitis through inhibiting NLRP3 inflammasome via triggering mitophagy - PMC
Journal
Immunity, inflammation and disease
Protocol to identify and analyze mouse and human quiescent hematopoietic stem cells using flow cytometry combined with confocal imaging - PMC
Mitochondrial cristae architecture protects against mtDNA release and inflammation