Naked mole-rat brown fat thermogenesis is diminished during hypoxia through a rapid decrease in UCP1
Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1/Lipin1 axis in an aging-related sarcopenia model
Journal
The Journal of clinical investigation
Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial
Journal
Journal of nanobiotechnology
Inhalation exposure to polystyrene nanoplastics induces chronic obstructive pulmonary disease-like lung injury in mice through multi-dimensional assessment
Journal
Environmental pollution (Barking, Essex : 1987)
TRPA1 promotes cisplatin-induced acute kidney injury via regulating the endoplasmic reticulum stress-mitochondrial damage - PMC
Journal
Journal of translational medicine
Species
Homo sapiens,Mus musculus
lncRNA ZNF593-AS inhibits cardiac hypertrophy and myocardial remodeling by upregulating Mfn2 expression
Journal
Frontiers of medicine
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis
Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress - PMC
Journal
Antioxidants (Basel, Switzerland)
Species
Mus musculus, Rattus norvegicus
Astragalin ameliorates renal injury in diabetic mice by modulating mitochondrial quality control via AMPK-dependent PGC1α pathway
Journal
Acta pharmacologica Sinica
Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction - PMC
Journal
Respiratory research
Puerarin prevents cadmium-induced mitochondrial fission in AML-12 cells via Sirt1-dependent pathway
Journal
Ecotoxicology and environmental safety
Ganoderic acid improves 5-fluorouracil-induced cognitive dysfunction in mice
Knockdown of insulin-like growth factor 2 gene disrupts mitochondrial functions in the liver
Mice harboring a R133L heterozygous mutation in LMNA exhibited ectopic lipid accumulation, aging, and mitochondrial dysfunction in adipose tissue
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Klf4 deficiency exacerbates myocardial ischemia/reperfusion injury in mice via enhancing ROCK1/DRP1 pathway-dependent mitochondrial fission
Journal
Journal of molecular and cellular cardiology
Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive …
Journal
Journal of ginseng research
Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic SIRT1/PGC-1 pathway
Journal
European journal of pharmacology
The apoptotic effects of soybean agglutinin were induced through three different signal pathways by down-regulating cytoskeleton proteins in IPEC-J2 cells - PMC
Journal
Scientific reports
Arsenic exposure induced renal fibrosis via regulation of mitochondrial dynamics and the NLRP3TGF1/SMAD signaling pathway
Journal
Environmental toxicology
Species
Homo sapiens,Rattus norvegicus
Glucose fluctuation accelerates cardiac injury of diabetic mice via sodium-dependent glucose cotransporter 1 (SGLT1)
Journal
Arch Biochem Biophys
Knockdown of SGLT1 prevents the apoptosis of cardiomyocytes induced by glucose fluctuation via relieving oxidative stress and mitochondrial dysfunction
Journal
Biochemistry and cell biology = Biochimie et biologie cellulaire
Mitochondrial fusion mediated by mitofusin 1 regulates macrophage mycobactericidal activity by enhancing autophagy
Journal
Infection and immunity
Schisandrin Restores the Amyloid β-Induced Impairments on Mitochondrial Function, Energy Metabolism, Biogenesis, and Dynamics in Rat Primary Hippocampal Neurons
GDF11, a target of miR-32-5p, suppresses high-glucose-induced mitochondrial dysfunction and apoptosis in HK-2 cells through PI3K/AKT signaling activation
Journal
International urology and nephrology