SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication - PMC
Journal
Signal transduction and targeted therapy
A novel sprayable thermosensitive hydrogel coupled with zinc modified metformin promotes the healing of skin wound - PMC
Journal
Bioactive materials
Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218
Genome-Scale CRISPR Screen Identifies LAPTM5 driving lenvatinib resistance in hepatocellular carcinoma
SPATA33 is an autophagy mediator for cargo selectivity in germline mitophagy
Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells - PMC
Journal
International journal of biological sciences
CircRNA-IGLL1/miR-15a/RNF43 axis mediates ammonia-induced autophagy in broilers jejunum via Wnt/β-catenin pathway
Repression of the AURKA-CXCL5 axis induces autophagic cell death and promotes radiosensitivity in non-small-cell lung cancer
FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages - PMC
Journal
Cell death & disease
Battery wastewater induces nephrotoxicity via disordering the mitochondrial dynamics
Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy - PMC
Alanyl-Glutamine Protects against Lipopolysaccharide-Induced Liver Injury in Mice via Alleviating Oxidative Stress, Inhibiting Inflammation, and Regulating Autophagy
Journal
Antioxidants (Basel, Switzerland)
SQSTM1/p62 Knockout by Using the CRISPR/Cas9 System Inhibits Migration and Invasion of Hepatocellular Carcinoma - PMC
BECLIN-1-Mediated Autophagy Suppresses Silica Nanoparticle-Induced Testicular Toxicity via the Inhibition of Caspase 8-Mediated Cell Apoptosis in Leydig Cells - PMC
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hexavalent chromium triggers hepatocytes premature senescence via the GATA4/NF-κB signaling pathway mediated by the DNA damage response
Journal
Ecotoxicology and environmental safety
Species
Homo sapiens,Mus musculus
Hexavalent chromium inhibits the formation of neutrophil extracellular traps and promotes the apoptosis of neutrophils via AMPK signaling pathway
Journal
Ecotoxicology and environmental safety
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1 - PMC
Journal
Cell death discovery
FK866 attenuates sepsis-induced acute lung injury through c-jun-N-terminal kinase (JNK)-dependent autophagy
nNovel insights into antidepressant mechanism of Kai Xin San formula: inhibiting NLRP3 inflammasome activation by promoting autophagy
Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis …
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Autophagy flux inhibition mediated by lysosomal dysfunction participates in the cadmium exposure-induced cardiotoxicity in swine
Journal
BioFactors (Oxford, England)
High PPT1 expression predicts poor clinical outcome and PPT1 inhibitor DC661 enhances sorafenib sensitivity in hepatocellular carcinoma
Journal
Cancer cell international
Species
Homo sapiens,Mus musculus
Downregulation of miR-29c promotes muscle wasting by modulating the activity of leukemia inhibitory factor in lung cancer cachexia
Modification of lysine deacetylation regulates curcumol-induced necroptosis through autophagy in hepatic stellate cells
Journal
Phytotherapy research : PTR
Calcium/calmodulin dependent protein kinase IV in trophoblast cells under insulin resistance: functional and metabolomic analyses - PMC
Journal
Molecular medicine (Cambridge, Mass.)
Long Non-Coding LEF1-AS1 Sponge miR-5100 Regulates Apoptosis and Autophagy in Gastric Cancer Cells via the miR-5100/DEK/AMPK-mTOR Axis
Journal
International journal of molecular sciences
Activation of Autophagy by Low-Dose Silica Nanoparticles Enhances Testosterone Secretion in Leydig Cells
Journal
International journal of molecular sciences
Defective Mitochondrial Dynamics and Protein Degradation Pathways Underlie Cadmium-Induced Neurotoxicity and Cell Death in Huntingtons Disease Striatal Cells - PMC
Journal
International journal of molecular sciences
Silica Nanoparticles Promote Apoptosis in Ovarian Granulosa Cells via Autophagy Dysfunction - PMC
Journal
International journal of molecular sciences
Species
Homo sapiens,Mus musculus
Mallotucin D, a Clerodane Diterpenoid from Croton crassifolius, Suppresses HepG2 Cell Growth via Inducing Autophagic Cell Death and Pyroptosis - PMC
Journal
International journal of molecular sciences
Olmesartan alleviates SARS-CoV-2 envelope protein induced renal fibrosis by regulating HMGB1 release and autophagic degradation of TGF-β1 - PMC
Journal
Frontiers in pharmacology
Species
Homo sapiens,Mus musculus
Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats
Journal
Frontiers in pharmacology
Glycyrrhizic acid improves tacrolimus‐induced renal injury by regulating autophagy
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Species
Mus musculus,Homo sapiens
Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
RRM2 Mediates the Anti-Tumor Effect of the Natural Product Pectolinarigenin on Glioblastoma Through Promoting CDK1 Protein Degradation by Increasing Autophagic Flux
Journal
Frontiers in oncology
A Self-Assembly ICG Nanoparticle Potentiating Targeted Photothermal and Photodynamic Therapy in NSCLC
Journal
ACS biomaterials science & engineering
Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR-29b-3p - PMC
Journal
International journal of molecular medicine
Aquaporin 5 maintains lens transparency by regulating the lysosomal pathway using circRNA
Journal
Journal of cellular and molecular medicine
Orphan nuclear receptor NUR77 relieves insulin resistance in HTR-8/SVneo trophoblast cells through activation of autophagy and insulin signaling
Journal
Journal of physiology and biochemistry
Nucleotide-binding oligomerization domain protein 1 enhances oxygen-glucose deprivation and reperfusion injury in cortical neurons via activation of endoplasmic reticulum stress-mediated autophagy
Clostridium butyricum Alleviates Gut Microbiota Alteration–Induced Bone Loss after Bariatric Surgery by Promoting Bone Autophagy
Journal
The Journal of pharmacology and experimental therapeutics
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy
Journal
Journal of atherosclerosis and thrombosis
Creatine ameliorates high-fat diet-induced obesity by regulation of lipolysis and lipophagy in brown adipose tissue and liver
Polyphyllin I induces apoptosis and autophagy in temozolomide-resistant glioma via modulation of NRF2 and MAPK-signaling activation
Journal
Biotechnology & genetic engineering reviews
Pralatrexate mediates effective killing of gemcitabine-resistant pancreatic cancer: role of mTOR/4E-BP1 signal pathway - PMC
Cr (VI)-induced overactive mitophagy contributes to mitochondrial loss and cytotoxicity in L02 hepatocytes
Journal
The Biochemical journal
Platonin Protects Against Cerebral Ischemia/Reperfusion Injury in Rats by Inhibiting NLRP3 Inflammasomes via BNIP3/LC3 Signaling Mediated Autophagy
MicroRNA?16?5p/BIMP1/NF?κB axis regulates autophagy to exert a tumor?suppressive effect on bladder cancer
Vitamin D alleviates hypoxia/reoxygenation-induced injury of human trophoblast HTR-8 cells by activating autophagy
Nicotinic Acid Riboside Regulates Nrf-2/P62-Related Oxidative Stress and Autophagy to Attenuate Doxorubicin-Induced Cardiomyocyte Injury
Journal
BioMed research international
UHMK1 promotes lung adenocarcinoma oncogenesis by regulating the PI3K/AKT/mTOR signaling pathway
Effects of RFRP-3 on an ovariectomized estrogen-primed rat model and HEC-1A human endometrial carcinoma cells - PMC
Journal
Experimental and therapeutic medicine
Isoschaftoside Reverses Nonalcoholic Fatty Liver Disease via Activating Autophagy In Vivo and In Vitro - PMC
Journal
Evidence-based complementary and alternative medicine : eCAM
Ginsenoside Rg3 protects heart against isoproterenol-induced myocardial infarction by activating AMPK mediated autophagy.
Journal
Cardiovascular Diagnosis and Therapy