Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC57399
产品形式
Liquid
偶联物
ABflo® 488. Ex:491nm. Em:516nm.
克隆号
ARC57399
产品形式
Liquid
偶联物
ABflo® 488. Ex:491nm. Em:516nm.
细胞定位
Cell membrane. Single-pass type I membrane protein
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
