Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC60934
产品形式
Liquid
偶联物
ABflo® 594. Ex:588nm. Em:604nm.
克隆号
ARC60934
产品形式
Liquid
偶联物
ABflo® 594. Ex:588nm. Em:604nm.
细胞定位
Cell membrane.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
This gene encodes an inhibitor of both the classical and the alternative pathways of complement activation. The encoded preproprotein undergoes post-translational processing to generate a mature polypeptide anchored to the plasma membrane via a glycosylphosphatidylinositol moiety. Erythrocytes from mice deficient in the encoded protein exhibit impaired regulation of complement activation resulting in enhanced complement deposition. Mice lacking the encoded protein exhibit enhanced susceptibility to experimentally induced myasthenia gravis. This gene is located adjacent to a closely related gene on chromosome 1.
