Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC52955
产品形式
Liquid
偶联物
ABflo® 594. Ex:588nm. Em:604nm.
克隆号
ARC52955
产品形式
Liquid
偶联物
ABflo® 594. Ex:588nm. Em:604nm.
细胞定位
Cell membrane, Cytoplasm, Single-pass type I membrane protein.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.