Flow cytometry analysis of mHSCs using PE Rabbit anti-Mouse CD117/c-Kit mAb (A24596) and ABflo® 488 Rabbit anti-Mouse CD150/SLAM mAb (A24971) at 1:1000 dilution. clearly classified positive and negative cells.
Enables identical protein binding activity and signaling receptor activity. Involved in natural killer cell activation; positive regulation of activated T cell proliferation; and regulation of cytokine production. Acts upstream of or within several processes, including leukocyte chemotaxis involved in inflammatory response; positive regulation of leukocyte chemotaxis; and regulation of vesicle fusion. Located in external side of plasma membrane and phagocytic vesicle. Is expressed in liver lobe. Orthologous to human SLAMF1 (signaling lymphocytic activation molecule family member 1).