Blockade of β-catenin signaling attenuates toluene diisocyanate-induced experimental asthma
Oxidative stress mediated by the TLR4/NOX2 signalling axis is involved in polystyrene microplastic-induced uterine fibrosis in mice
Journal
The Science of the total environment
A self-assembling peptide hydrogel-based drug co-delivery platform to improve tissue repair after ischemia-reperfusion injury
Journal
Acta Biomaterialia
Liraglutide abrogates nephrotoxic effects of chemotherapies
Journal
Pharmacological research
Species
Homo sapiens, Mus musculus
YAP induces FAK phosphorylation to inhibit gastric cancer cell proliferation via upregulation of HMGB1
Journal
International journal of biological macromolecules
Carbonic anhydrase IX inhibitor S4 triggers release of DAMPs related to immunogenic cell death in glioma cells via endoplasmic reticulum stress pathway - PMC
Journal
Cell communication and signaling : CCS
Dexmedetomidine attenuates perioperative neurocognitive disorders by suppressing hippocampal neuroinflammation and HMGB1/RAGE/NF-κB signaling pathway
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
The von Hippel-Lindau Tumor Suppressor Gene Mutations Modulate Lipocalin-2 Expression in Ferroptotic-Inflammatory Pathways - PMC
Journal
Oxidative medicine and cellular longevity
Protective effect and mechanism of baicalin on lung inflammatory injury in BALB/cJ mice induced by PM2. 5
Journal
Ecotoxicology and environmental safety
Enriched housing promotes post-stroke functional recovery through astrocytic HMGB1-IL-6-mediated angiogenesis
Journal
Cell death & disease
Enhanced therapeutic efficacy of doxorubicin against multidrug-resistant breast cancer with reduced cardiotoxicity - PMC
The Ameliorative Role of Lico A on Aflatoxin B1-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway
Journal
Journal of agricultural and food chemistry
The Ameliorative Role of Lico A on Aflatoxin B1-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway
Journal
Journal of agricultural and food chemistry
Cold Stress Induced Liver Injury of Mice through Activated NLRP3/Caspase-1/GSDMD Pyroptosis Signaling Pathway - PMC
The LPS induced pyroptosis exacerbates BMPR2 signaling deficiency to potentiate SLEPAH
The receptor for advanced glycation end products mediates dysfunction of airway epithelial barrier in a lipopolysaccharides-induced murine acute lung injury model
Journal
Int Immunopharmacol
3, 3'- diindolylmethane hinders IL-17A/IL-17RA interaction and mitigates imiquimod-induced psoriasiform in mice
Journal
International immunopharmacology
Corynoxine B ameliorates HMGB1-dependent autophagy dysfunction during manganese exposure in SH-SY5Y human neuroblastoma cells.
Journal
Food and chemical toxicology
HMGB1 is mechanistically essential in the development of experimental pulmonary hypertension.
Journal
American journal of physiology. Cell physiology
Recombinant Human Annexin A5 Alleviated Traumatic-Brain-Injury Induced Intestinal Injury by Regulating the Nrf2/HO-1/HMGB1 Pathway - PMC
Journal
Molecules (Basel, Switzerland)
RNA helicase DHX33 regulates HMGB family genes in human cancer cells
Journal
Cellular signalling
Programmed cell death 10 increased blood-brain barrier permeability through HMGB1/TLR4 mediated downregulation of endothelial ZO-1 in glioblastoma
Journal
Cellular signalling
Prenylated Bibenzyls from the Chinese Liverwort Radula constricta and Their Mitochondria-Derived Paraptotic Cytotoxic Activities.
Journal
Cytogenetic and genome research
Maresin-1 Attenuates Sepsis-Associated Acute Kidney Injury via Suppressing Inflammation, Endoplasmic Reticulum Stress and Pyroptosis by Activating the AMPK/SIRT3 Pathway - PMC
Journal
Journal of inflammation research
Increasedbutyrateprimingin thegutstallsmicrobiomeassociated-gastrointestinalinflammationandhepaticmetabolicreprogrammingin amousemodelofGulfWarIllness.
Journal
Toxicology and Applied pharmacology
Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses
Journal
Toxicol Appl Pharmacol
18-Glycyrrhetinic Acid Alleviates P. multocida-Induced Vascular Endothelial Inflammation by PARP1-Mediated NF-B and HMGB1 Signalling Suppression in PIEC Cells - PMC
Journal
Infection and drug resistance
HMGB1-TLR4 signaling participates in renal ischemia reperfusion injury and could be attenuated by dexamethasone-mediated inhibition of the ERK/NF-κB pathway.
Journal
American Journal of Translational Research
Enriched housing promotes post-stroke neurogenesis through calpain 1-STAT3/HIF-1/VEGF signaling
Journal
Brain research bulletin
Rosuvastatin suppresses TNF--induced matrix catabolism, pyroptosis and senescence via the HMGB1/NF-B signaling pathway in nucleus pulposus cells - PMC
Journal
Acta biochimica et biophysica Sinica
IGF-1 alleviates CCL4-induced hepatic cirrhosis and dysfunction of intestinal barrier through inhibition TLR4/NF-κB signaling mediated by down-regulation HMGB1
Involvement of high-mobility group box 1 in the pathogenesis of severe 1 hemolytic uremic syndrome in a murine model
Journal
American Journal of Physiology - Renal Physiology
SIRT1-mediated HMGB1 deacetylation suppresses sepsis-associated acute kidney injury.
Journal
American journal of physiology. Renal physiology
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy - PMC
miR-495-3p depresses cell proliferation and migration by downregulating HMGB1 in colorectal cancer
Journal
World journal of surgical oncology
Lycorine attenuates lipopolysaccharide-induced acute lung injury through the HMGB1/TLRs/NF-κB pathway