Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC59425
产品形式
Liquid
偶联物
PE. Ex:565nm. Em:574nm.
克隆号
ARC59425
产品形式
Liquid
偶联物
PE. Ex:565nm. Em:574nm.
细胞定位
Plasma membrane, Cell junction, Secreted.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Flow Cytometry analysis of mouse spleen single-cell suspensions, using PE Rabbit anti-Mouse CD366 (TIM-3) mAb (A25729) and ABflo® 450 Rabbit anti-Mouse CD8a mAb (A25943). The staining clearly distinguished between positive and negative cell populations.
Predicted to enable metal ion binding activity. Involved in several processes, including regulation of cytokine production; regulation of leukocyte activation; and toll-like receptor signaling pathway. Located in cell surface; early endosome; and immunological synapse. Is expressed in several structures, including dorsal aorta; gut; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and renal cell carcinoma. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2).
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