Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells
Burkholderia pseudomallei BipD modulates host mitophagy to evade killing - PMC
Journal
Nature communications
TMEM135 maintains the equilibrium of osteogenesis and adipogenesis by regulating mitochondrial dynamics
Journal
Metabolism: clinical and experimental
Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production
m6A methylation-induced NR1D1 ablation disrupts the HSC circadian clock and promotes hepatic fibrosis
Journal
Pharmacological research
Mitochondrial dynamics and mitophagy involved in MPA-capped CdTe quantum dots-induced toxicity in the human liver carcinoma (HepG2) cell line
Journal
Environmental pollution (Barking, Essex : 1987)
piR-823 inhibits cell apoptosis via modulating mitophagy by binding to PINK1 in colorectal cancer
Journal
Cell death & disease
Enrofloxacin (ENR) exposure induces lipotoxicity by promoting mitochondrial fragmentation via dephosphorylation of DRP1 at S627 site
Altered synaptic currents, mitophagy, mitochondrial dynamics in Alzheimer's disease models and therapeutic potential of Dengzhan Shengmai Capsules
Journal
Journal of pharmaceutical analysis
TRPA1 promotes cisplatin-induced acute kidney injury via regulating the endoplasmic reticulum stress-mitochondrial damage - PMC
Journal
Journal of translational medicine
Species
Homo sapiens,Mus musculus
Melatonin attenuates bisphenol A-induced colon injury by dual targeting mitochondrial dynamics and Nrf2 antioxidant system via activation of SIRT1/PGC-1α signaling …
Journal
Free radical biology & medicine
Differential Expression of Lonp1 Isoforms in Cancer Cells - PMC
Inhibition of mitochondrial fusion via SIRT1/PDK2/PARL axis breaks mitochondrial metabolic plasticity and sensitizes cancer cells to glucose restriction
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
HSPB8 Overexpression Ameliorates Cognitive Impairment in Diabetic Mice via Inhibiting NLRP3 Inflammation Activation
Journal
Oxidative medicine and cellular longevity
Astragalin ameliorates renal injury in diabetic mice by modulating mitochondrial quality control via AMPK-dependent PGC1α pathway
Journal
Acta pharmacologica Sinica
Clusterin alleviates Cr (VI)-induced mitochondrial apoptosis in L02 hepatocytes via inhibition of Ca2+-ROS-Drp1-mitochondrial fission axis
Journal
Ecotoxicol Environ Saf
Drp1-dependent mitochondrial fission contributes to Cr (VI)-induced mitophagy and hepatotoxicity
Journal
Ecotoxicol Environ Saf
Electrical Pulse Stimulation Protects C2C12 Myotubes against Hydrogen Peroxide-Induced Cytotoxicity via Nrf2/Antioxidant Pathway - PMC
Journal
Antioxidants (Basel, Switzerland)
Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
SIRT1 activation by SRT1720 attenuates bone cancer pain via preventing Drp1-mediated mitochondrial fission.
Journal
Biochimica et biophysica acta. Molecular basis of disease
Aerobic exercise improves mitochondrial function in sarcopenia mice through Sestrin2 in an AMPKα2-dependent manner
Journal
The journals of gerontology. Series A, Biological sciences and medical sciences
Role of mitochondria-endoplasmic reticulum coupling in lycopene preventing DEHP-induced hepatotoxicity
Knockdown of insulin-like growth factor 2 gene disrupts mitochondrial functions in the liver
Defective Mitochondrial Dynamics and Protein Degradation Pathways Underlie Cadmium-Induced Neurotoxicity and Cell Death in Huntingtons Disease Striatal Cells - PMC
Journal
International journal of molecular sciences
Galectin-7 promotes cisplatin efficacy by facilitating apoptosis and G3BP1 degradation in cervical cancer
Journal
Biochemical pharmacology
Exposure effects of inhaled nickel nanoparticles on the male reproductive system via mitochondria damage
Ginsenoside Rg5 Improves Sleep by Regulating Energy Metabolism in Sleep-Deprived Rats
Journal
The American journal of Chinese medicine
Squamosamide Derivative FLZ Diminishes Aberrant Mitochondrial Fission by Inhibiting Dynamin-Related Protein 1
Klf4 deficiency exacerbates myocardial ischemia/reperfusion injury in mice via enhancing ROCK1/DRP1 pathway-dependent mitochondrial fission
Journal
Journal of molecular and cellular cardiology
Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive …
Journal
Journal of ginseng research
AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease
Journal
Experimental neurology
Inhibition of DNM1L and mitochondrial fission attenuates inflammatory response in fibroblast-like synoviocytes of rheumatoid arthritis
Journal
Journal of Cellular and Molecular Medicine
Glycogen synthase kinase-3 inhibition decreases inflammation and relieves cancer induced bone pain via reducing Drp1-mediated mitochondrial damage - PMC
Journal
Journal of cellular and molecular medicine
LCitrulline Ameliorates Iron Metabolism and Mitochondrial Quality Control via Activating AMPK Pathway in Intestine and Improves Microbiota in Mice with Iron
Journal
Molecular nutrition & food research
ATPAF1 deficiency impairs ATP synthase assembly and mitochondrial respiration
Exercise ameliorating myocardial injury in type 2 diabetic rats by inhibiting excessive mitochondrial fission involving increased irisin expression and AMPactivated
Journal
Journal of diabetes
Arsenic exposure induced renal fibrosis via regulation of mitochondrial dynamics and the NLRP3TGF1/SMAD signaling pathway
Journal
Environmental toxicology
Species
Homo sapiens,Rattus norvegicus
Increased Mitochondrial Fragmentation Mediated by Dynamin-Related Protein 1 Contributes to Hexavalent Chromium-Induced Mitochondrial Respiratory Chain Complex I-Dependent Cytotoxicity
The effects of dual IQOS and cigarette smoke exposure on airway epithelial cells: implications for lung health and respiratory disease pathogenesis - PMC
Glucose fluctuation accelerates cardiac injury of diabetic mice via sodium-dependent glucose cotransporter 1 (SGLT1)
Journal
Arch Biochem Biophys
Sodium Tanshinone IIA Sulfonate Attenuates Cigarette Smoke Extract-Induced Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Alveolar Epithelial Cells by Enhancing SIRT1 Pathway
Journal
Toxicological sciences : an official journal of the Society of Toxicology
Modified rougan decoction attenuates hepatocyte apoptosis through ameliorating mitochondrial dysfunction by upregulated SIRT1/PGC-1 signaling pathway - PMC
2-Bromopalmitate decreases spinal inflammation and attenuates oxaliplatin-induced neuropathic pain via reducing Drp1-mediated mitochondrial dysfunction - PMC
Knockdown of SGLT1 prevents the apoptosis of cardiomyocytes induced by glucose fluctuation via relieving oxidative stress and mitochondrial dysfunction
Journal
Biochemistry and cell biology = Biochimie et biologie cellulaire
Levosimendan protects from sepsis-inducing cardiac dysfunction by suppressing inflammation, oxidative stress and regulating cardiac mitophagy via the PINK-1-Parkin pathway in mice
Journal
Annals of translational medicine
Homocysteine induced a calcium-mediated disruption of mitochondrial function and dynamics in endothelial cells
Journal
J Biochem Mol Toxicol
Effect of oligonol, a lychee-derived polyphenol, on skeletal muscle in ovariectomized rats by regulating body composition, protein turnover, and mitochondrial quality signaling
Journal
Food science & nutrition
2-Bromopalmitate attenuates inflammatory pain by maintaining mitochondrial fission/fusion balance and function
Journal
Acta biochimica et biophysica Sinica
Resveratrol suppresses bone cancer pain in rats by attenuating inflammatory responses through the AMPK/Drp1 signaling
Journal
Acta Biochimica et Biophysica Sinica
Angiotensin II type 1a receptor knockout ameliorates high-fat diet-induced cardiac dysfunction by regulating glucose and lipid metabolism - PMC
Journal
Acta biochimica et biophysica Sinica
2-Bromopalmitate attenuates bone cancer pain via reversing mitochondrial fusion and fission imbalance in spinal astrocytes.
Txnip Gene Knockout Ameliorated High-Fat Diet-Induced Cardiomyopathy Via Regulating Mitochondria Dynamics and Fatty Acid Oxidation - PMC
Journal
Journal of cardiovascular pharmacology
Transfer of massive mitochondria from astrocytes reduce propofol neurotoxicity
Journal
Neuroscience letters
Mitochondrial Dynamics in Rat Heart Induced by 5-Fluorouracil
Journal
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
GDF11, a target of miR-32-5p, suppresses high-glucose-induced mitochondrial dysfunction and apoptosis in HK-2 cells through PI3K/AKT signaling activation
Journal
International urology and nephrology