Flow cytometry analysis of mouse lymphocyte using ABflo® 500 Rabbit anti-Mouse CD8a mAb (A27333), ABflo® 700 Rabbit anti-Mouse CD45 mAb (A27198), PE/Cyanine7 anti-Mouse TCR β chain mAb (A27382), ABflo® 488 Rabbit anti-Mouse FOXP3 mAb (A26228), PE Rabbit anti-Mouse IL-33R/ST2 mAb (A26381) and ABflo® 450 Rabbit anti-Mouse CD4 mAb (A25941) at 1:50 dilution. clearly classified positive and negative cells.
Flow cytometry analysis of mouse spleen cells using ABflo® 700 Rabbit anti-Mouse CD8a mAb (A25944) and ABflo® 450 Rabbit anti-Mouse CD4 mAb (A25941) at 1:200 dilution. clearly classified positive and negative cells.
Predicted to enable several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in helper T cell enhancement of adaptive immune response. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; positive regulation of calcium-mediated signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Located in endoplasmic reticulum; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).
