Flow Cytometry analysis of mouse spleen single-cell suspensions, using PE Rabbit anti-Mouse CD366 (TIM-3) mAb (A25729) and ABflo® 450 Rabbit anti-Mouse CD8a mAb (A25943). The staining clearly distinguished between positive and negative cell populations.
Enables identical protein binding activity. Acts upstream of or within several processes, including cytotoxic T cell differentiation; defense response to virus; and positive regulation of calcium-mediated signaling. Located in external side of plasma membrane. Is expressed in several structures, including endocrine gland; exocrine gland; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human CD8A (CD8a molecule).
