Gut Microbiota Participates in Polystyrene Microplastics-Induced Hepatic Injuries by Modulating the GutLiver Axis
EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses - PMC
Journal
Nature communications
Gut microbiota-derived ursodeoxycholic acid from neonatal dairy calves improves intestinal homeostasis and colitis to attenuate extended-spectrum β-lactamase-producing enteroaggregative Escherichia coli infection
AKT activation by SC79 to transiently re-open pathological blood brain barrier for improved functionalized nanoparticles therapy of glioblastoma
Daucosterol confers protection against T-2 toxin induced blood-brain barrier toxicity through the PGC-1-mediated defensive response in vitro and in vivo
Journal
Journal of hazardous materials
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens
Journal
Journal of hazardous materials
Polystyrene micro-and nanoplastics induce gastric toxicity through ROS mediated oxidative stress and P62/Keap1/Nrf2 pathway
Journal
The Science of the total environment
Atrial Natriuretic Peptide Attenuates Colitis via Inhibition of the cGAS-STING Pathway in Colonic Epithelial Cells
Journal
International journal of biological sciences
Species
Homo sapiens, Mus musculus
Gut microbiota remodeling improves natural aging-related disorders through Akkermansia muciniphila and its derived acetic acid
Journal
Pharmacological research
Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis
Journal
Environmental pollution (Barking, Essex : 1987)
Gestational PCB52 exposure induces hepatotoxicity and intestinal injury by activating inflammation in dam and offspring mice: A maternal and progeny study
Journal
Environmental pollution (Barking, Essex : 1987)
Gastrointestinal microbiome of ARDS patients induces neuroinflammation and cognitive impairment in mice - PMC
Journal
Journal of neuroinflammation
The Role of Vasoactive Intestinal Peptide and Mast Cells in the Regulatory Effect of Lactobacillus casei ATCC 393 on Intestinal Mucosal Immune Barrier
Intestinal Mucosal Immunity-Mediated Modulation of the Gut Microbiome by Oral Delivery of Enterococcus faecium Against Salmonella Enteritidis Pathogenesis in a Laying Hen Model
Journal
Frontiers in immunology
Inhibition of CREB-mediated ZO-1 and Activation of NF-B-induced IL-6 by Colonic Epithelial MCT4 Destroys Intestinal Barrier Function.
Journal
Cell Proliferation
Species
Homo sapiens, Mus musculus
Extracellular vesicles derived from EphB2-overexpressing bone marrow mesenchymal stem cells ameliorate DSS-induced colitis by modulating immune balance
Journal
Stem Cell Res Ther
Echinacea purpurea polysaccharide prepared by fractional precipitation prevents alcoholic liver injury in mice by protecting the intestinal barrier and regulating liver-related pathways
Journal
Int J Biol Macromol
Gardenia jasminoides Ellis polysaccharide ameliorates cholestatic liver injury by alleviating gut microbiota dysbiosis and inhibiting the TLR4/NF-B signaling pathway
Journal
International journal of biological macromolecules
Neuroprotective effects of polysaccharide from Sparassis crispa on Alzheimer's disease-like mice: Involvement of microbiota-gut-brain axis
Journal
International journal of biological macromolecules
An Antioxidant Supplement Function Exploration: Rescue of Intestinal Structure Injury by Mannan Oligosaccharides after Aeromonas hydrophila Infection in Grass Carp ( Ctenopharyngodon idella )
Journal
Antioxidants (Basel, Switzerland)
Ulcerative Colitis in Response to Fecal Microbiota Transplantation via Modulation of Gut Microbiota and Th17/Treg Cell Balance - PMC
Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells
Journal
Biological Research
BAFF Blockade Attenuates Inflammatory Responses and Intestinal Barrier Dysfunction in a Murine Endotoxemia Model
Journal
Frontiers in Immunology
GJ-4 alleviates Aβ25-35-induced memory dysfunction in mice through protecting the neurovascular unit
Journal
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
Paneth Cells Protect against Acute Pancreatitis via Modulating Gut Microbiota Dysbiosis
Species
Homo sapiens, Mus musculus
Biogenic Selenium Nanoparticles Alleviate Intestinal Epithelial Barrier Damage through Regulating Endoplasmic Reticulum Stress-Mediated Mitophagy - PMC
Journal
Oxidative medicine and cellular longevity
JNK molecule is a toxic target for IPEC-J2 cell barrier damage induced by T-2 toxin
Journal
Ecotoxicology and environmental safety
Omentin-1 ameliorates experimental inflammatory bowel disease via Nrf2 activation and redox regulation
Species
Homo sapiens, Mus musculus
Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization
Rhein ameliorates lipopolysaccharide-induced intestinal barrier injury via modulation of Nrf2 and MAPKs.
Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Glycerol monolaurate ameliorates DSS-induced acute colitis by inhibiting infiltration of Th17, neutrophils, macrophages and altering the gut microbiota - PMC
Journal
Frontiers in nutrition
Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization - PMC
Journal
Frontiers in nutrition
Deoxynivalenol Exposure Induced Colon Damage in Mice Independent of the Gut Microbiota
Journal
Molecular nutrition & food research
Lab-Attenuated Rabies Virus Facilitates Opening of the Blood-Brain Barrier by Inducing Matrix Metallopeptidase 8
Journal
Journal of virology
Tembusu Virus entering the central nervous system caused nonsuppurative encephalitis without disrupting the blood-brain barrier
Journal
Journal of virology
Borneol-modified PEGylated graphene oxide as a nanocarrier for brain-targeted delivery of ginsenoside Rg1 against depression
Journal
International journal of pharmaceutics
Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis - PMC
Journal
Molecular medicine (Cambridge, Mass.)
Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis - PMC
Journal
Molecular medicine (Cambridge, Mass.)
Procyanidin A1 and its digestive products prevent acrylamide-induced intestinal barrier dysfunction via the MAPK-mediated MLCK pathway
Preparation, characterization, and in vivo evaluation of anti-inflammatory activities of selenium nanoparticles synthesized by Kluyveromyces lactis GG799
Lactobacillus plantarum Y44 alleviates oxidative stress by regulating gut microbiota and colonic barrier function in Balb/C mice with subcutaneous D-galactose injection
Isomaltulose alleviates acute colitis via modulating gut microbiota and the Treg/Th17 balance in mice
Preventive Effect of Pectic Oligosaccharides on Acute Colitis Model Mice: Modulating Epithelial Barrier, Gut Microbiota and Treg/Th17 Balance
The preventive effect and underlying mechanism of Rhus chinensis Mill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice
Replacing dietary sodium selenite with biogenic selenium nanoparticles improves the growth performance and gut health of early-weaned piglets
Dexmedetomidine post-conditioning protects blood-brain barrier integrity by modulating microglia/macrophage polarization via inhibiting NF-κB signaling pathway in intracerebral hemorrhage - PMC
Journal
Frontiers in molecular neuroscience
Dietary Leucine Improves Fish Intestinal Barrier Function by Increasing Humoral Immunity, Antioxidant Capacity, and Tight Junction - PMC
Journal
International journal of molecular sciences
Species
Horabagrus nigricollaris
Resveratrol alleviates oxidative stress induced by oxidized soybean oil and improves gut function via changing gut microbiota in weaned piglets - PMC
Journal
Journal of animal science and biotechnology
Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells—implications for blood-brain barrier physiology in Friedreichs ataxia - PMC
Journal
Frontiers in molecular biosciences
The Immunity Protection of Central Nervous System Induced by Pseudorabies Virus DelgI/gE/TK in Mice
Journal
Frontiers in microbiology
Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice
Journal
Frontiers in microbiology
Obacunone Protects Against Ulcerative Colitis in Mice by Modulating Gut Microbiota, Attenuating TLR4/NF-κB Signaling Cascades, and Improving Disrupted Epithelial Barriers
Journal
Frontiers in Microbiology
Lactobacillus frumenti Facilitates Intestinal Epithelial Barrier Function Maintenance in Early-Weaned Piglets
Journal
Frontiers in microbiology
Tetramethylpyrazine Ameliorates Lipopolysaccharide-Induced Sepsis in Rats via Protecting Blood-Brain Barrier, Impairing Inflammation and Nitrous Oxide Systems
Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial -glucuronidase
Oryzanol Ameliorates DSS-Stimulated Gut Barrier Damage via Targeting the Gut Microbiota Accompanied by the TLR4/NF-κB/NLRP3 Cascade Response In Vivo
Journal
Journal of agricultural and food chemistry
Sleep Deprivation Impairs Intestinal Mucosal Barrier by Activating Endoplasmic Reticulum Stress in Goblet Cells
Journal
The American journal of pathology
HSF1 enhances the attenuation of exosomes from mesenchymal stem cells to hemorrhagic shock induced lung injury by altering the protein profile of
Journal
International immunopharmacology
Taurine protects blood-milk barrier integrity via limiting inflammatory response in Streptococcus uberis infections
Journal
International immunopharmacology
Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Saccharina japonica Ethanol Extract Ameliorates Dextran Sulfate Sodium-Induced Colitis via Reshaping Intestinal Microenvironment and Alleviating Inflammatory Response - PMC
Journal
Foods (Basel, Switzerland)
Neonatal Injury Increases Gut Permeability by Epigenetically Suppressing E-Cadherin in Adulthood
Journal
Journal of Immunology (Baltimore, Md. : 1950)
Tamarind Seed Polysaccharide Hydrolysate Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis via Regulating the Gut Microbiota - PMC
Journal
Pharmaceuticals (Basel, Switzerland)
Ameliorative effects of chlorogenic acid on alcoholic liver injury in mice via gut microbiota informatics
Journal
European journal of pharmacology
Xueshuantong injection alleviates cerebral microcirculation disorder in middle cerebral artery occlusion/reperfusion rats by suppressing inflammation via JNK …
Journal
Journal of ethnopharmacology
Application
ICH, ELISA, WB
Acute sleep deprivation exacerbates systemic inflammation and psychiatry disorders through gut microbiota dysbiosis and disruption of circadian rhythms
Journal
Microbiological research
Protective Effects of Selenium Nanoparticle-Enriched Lactococcus lactis NZ9000 against Enterotoxigenic Escherichia coli K88-Induced Intestinal Barrier Damage in Mice
Journal
Applied and environmental microbiology
Naringin Exhibited Therapeutic Effects against DSS-Induced Mice Ulcerative Colitis in Intestinal Barrier-Dependent Manner
Recombinant Human Annexin A5 Alleviated Traumatic-Brain-Injury Induced Intestinal Injury by Regulating the Nrf2/HO-1/HMGB1 Pathway - PMC
Journal
Molecules (Basel, Switzerland)
Inulin supplementation ameliorates hyperuricemia and modulates gut microbiota in Uox-knockout mice
Dysbiosis-Associated Enteric Glial Cell Immune-Activation and Redox Imbalance Modulate Tight Junction Protein Expression in Gulf War Illness Pathology.
Journal
Frontiers in Physiology
Lycopene Affects Intestinal Barrier Function and the Gut Microbiota in Weaned Piglets Via Antioxidant Signaling Regulation
Journal
The Journal of nutrition
Impact of Plasticizer on the Intestinal Epithelial Integrity and Tissue-Repairing Ability within Cells in the Proximity of the Human Gut Microbiome - PMC
Journal
International journal of environmental research and public health
Polystyrene microplastics aggravate acute pancreatitis in mice
Obeticholic acid protects against methamphetamine-induced anxiety-like behavior by ameliorating microbiota-mediated intestinal barrier impairment
Atractylenolide III Improves Mitochondrial Function and Protects Against Ulcerative Colitis by Activating AMPK/SIRT1/PGC-1
Journal
Mediators of inflammation
Neuroprotection of Resveratrol Against Focal Cerebral Ischemia/Reperfusion Injury in Mice Through a Mechanism Targeting Gut-Brain Axis.
Journal
Cellular and molecular neurobiology
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells - PMC
The Effects of the Extract from Peanut Meal Fermented with Bacillus natto and Monascus on Lipid Metabolism and Intestinal Barrier Function of Hyperlipidemia in Mice
Biogenic Selenium Nanoparticles Synthesized by Lactobacillus casei ATCC 393 Alleviate Acute Hypobaric Hypoxia-Induced Intestinal Barrier Dysfunction in C57BL/6 …
Journal
Biological trace element research
Polygonatum odoratum polysaccharide attenuates lipopolysaccharideinduced lung injury in mice by regulating gut microbiota
Journal
Food science & nutrition
Impaired intestinal barrier function in a mouse model of hyperuricemia.
Journal
Molecular medicine reports
Apolipoprotein E mimetic peptide COG1410 alleviates blood‑brain barrier injury in a rat model of ischemic stroke
Journal
Molecular medicine reports
Dietary trace mineral pattern influences gut microbiota and intestinal health of broilers
Journal
Journal of animal science
Species
Canis lupus familiaris
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy - PMC
Protective effects of prucalopride in MPTP-induced Parkinson's disease mice: Neurochemistry, motor function and gut barrier
Journal
Biochem Biophys Res Commun
NCOA4-mediated ferritinophagy aggravate intestinal oxidative stress and ferroptosis after traumatic brain injury
Journal
Biochemical and biophysical research communications
Dapagliflozin modulates the fecal microbiota after myocardial infarction in non‐diabetic mice
Journal
Clinical and experimental pharmacology & physiology
Protective mechanism of selenium on mercuric chloride-induced testis injury in chicken via p38 MAPK/ATF2/iNOS signaling pathway
Establishment of an astrocyte‐like cell line from the brain of tilapia (Oreochromis niloticus) for virus pathogenesis and a vitro model of the blood–brain barrier
Journal
Journal of fish diseases
Species
Oreochromis niloticus
Co-infection with porcine bocavirus and porcine circovirus 2 affects inflammatory cytokine production and tight junctions of IPEC-J2 cells.
Suppressing mortality and curbing cellular damage by targeting VHL
Journal
bioRxiv : the preprint server for biology
Protective effect and mechanism insight of purified Antarctic kill phospholipids against mice ulcerative colitis combined with bioinformatics - PMC
Journal
Natural products and bioprospecting
Akkermansia supplementation reverses the tumor-promoting effect of the fecal microbiota transplantation in ovarian cancer
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment
Journal
Materials today. Bio