Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC66962
产品形式
Liquid
偶联物
ABflo® 488. Ex:491nm. Em:516nm.
克隆号
ARC66962
产品形式
Liquid
偶联物
ABflo® 488. Ex:491nm. Em:516nm.
细胞定位
Cell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
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