APC Rabbit anti-Mouse CD309/VEGFR2 mAb (A30030)

Enables coreceptor activity; growth factor binding activity; and vascular endothelial growth factor receptor activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of BMP signaling pathway; and positive regulation of cell migration involved in sprouting angiogenesis. Acts upstream of or within several processes, including positive regulation of cell population proliferation; post-embryonic camera-type eye morphogenesis; and vasculature development. Located in several cellular components, including cell junction; endosome; and external side of plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); breast angiosarcoma; gastrointestinal system cancer (multiple); macular degeneration (multiple); and pancreatic cancer (multiple). Orthologous to human KDR (kinase insert domain receptor).