Surplus fatty acid synthesis increases oxidative stress in adipocytes and lnduces lipodystrophy - PMC
Journal
Nature communications
A NRF2 Regulated and the Immunosuppressive Microenvironment Reversed Nanoplatform for Cholangiocarcinoma PhotodynamicGas Therapy
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Loss of RPA1 Impairs Peripheral T Cell Homeostasis and Exacerbates Inflammatory Damage through Triggering T Cell Necroptosis
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis
Species
Ctenopharyngodon idellus
Regulation of H 2 S-induced necroptosis and inflammation in broiler bursa of Fabricius by the miR-15b-5p/TGFBR3 axis and the involvement of oxidative stress in this process
Hydrogen sulfide exposure induces apoptosis and necroptosis through lncRNA3037/miR-15a/BCL2-A20 signaling in broiler trachea.
Journal
The Science of the Total Environment
Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-B signaling pathways in LPS-activated BV-2 microglia
Journal
Pharmacological Research
NIR-responsive CN-Pt-GEM hydrogel induces necroptosis and immunotherapeutic responses prevent postoperative recurrence and wound infection in lung carcinoma - PMC
Journal
Journal of nanobiotechnology
XJB-5-131 inhibited ferroptosis in tubular epithelial cells after ischemia− reperfusion injury
Mitochondrial Dysfunction by FADDosome Promotes Gastric Mucosal Injury in Portal Hypertensive Gastropathy - PMC
Journal
International journal of biological sciences
Mitochondrial Dysfunction by FADDosome Promotes Gastric Mucosal Injury in Portal Hypertensive Gastropathy - PMC
Journal
International journal of biological sciences
Mitochondrial Dysfunction by FADDosome Promotes Gastric Mucosal Injury in Portal Hypertensive Gastropathy - PMC
Journal
International journal of biological sciences
Mitochondrial Dysfunction by FADDosome Promotes Gastric Mucosal Injury in Portal Hypertensive Gastropathy - PMC
Journal
International journal of biological sciences
Melatonin attenuates bisphenol A-induced colon injury by dual targeting mitochondrial dynamics and Nrf2 antioxidant system via activation of SIRT1/PGC-1α signaling …
Journal
Free radical biology & medicine
Mercuric chloride induces sequential activation of ferroptosis and necroptosis in chicken embryo kidney cells by triggering ferritinophagy
Journal
Free radical biology & medicine
Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimers disease by inhibiting neuroinflammation and neuronal necroptosis - PMC
DHA attenuates Aβ-induced necroptosis through the RIPK1/RIPK3 signaling pathway in THP-1 monocytes
Journal
Biomedicine & Pharmacotherapy
Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
1, 8-cineole alleviates bisphenol A-induced apoptosis and necroptosis in bursa of Fabricius in chicken through regulating oxidative stress and PI3K/AKT pathway
Journal
Ecotoxicol Environ Saf
Cadmium exposure causes mitochondrial fission and fusion disorder in the pig hypothalamus via the PI3K/AKT pathway
Journal
Ecotoxicology and environmental safety
RIPK3 activation promotes DAXXdependent neuronal necroptosis after intracerebral hemorrhage in mice
Journal
CNS neuroscience & therapeutics
S-adenosyl-L-methionine supplementation alleviates the destructed intestinal epithelium and inflammatory infiltration caused by Mat2a deficiency
Journal
Development (Cambridge, England)
Investigation on the expression regulation of RIPK1/RIPK3 in the retinal ganglion cells (RGCs) cultured in high glucose
Membrane protein-chimeric liposome-mediated delivery of triptolide for targeted hepatocellular carcinoma therapy
HSP90α Mediates Sorafenib Resistance in Human Hepatocellular Carcinoma by Necroptosis Inhibition under Hypoxia
Baicalin ameliorates Mycoplasma gallisepticum-induced inflammatory injury in the chicken lung through regulating the intestinal microbiota and phenylalanine metabolism
RNA-sequencing approach for exploring the protective mechanisms of dexmedetomidine on pancreatic injury in severe acute pancreatitis - PMC
Journal
Frontiers in pharmacology
Low-Dose Resveratrol Inhibits RIPK3-Mediated Necroptosis and Delays the Onset of Age-Related Hearing Loss - PMC
Journal
Frontiers in pharmacology
AZ-628 delays osteoarthritis progression via inhibiting the TNF--induced chondrocyte necroptosis and regulating osteoclast formation
Journal
International immunopharmacology
Application
WB, IHC, IF, ELISA
Ursolic acid improves necroptosis via STAT3 signaling in intestinal ischemia/reperfusion injury
Journal
International immunopharmacology
Eucalyptol alleviates avermectin exposure-induced apoptosis and necroptosis of grass carp hepatocytes by regulating ROS/NLRP3 axis
Journal
Aquatic toxicology (Amsterdam, Netherlands)
Species
Ctenopharyngodon idellus
Oroxyloside ameliorates acetaminophen-induced hepatotoxicity by inhibiting JNK related apoptosis and necroptosis
Journal
Journal of Ethnopharmacology
The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process
Journal
Molecular and cellular biology
Receptor-interacting serine/threonine kinase 1- and 3-dependent inflammation induced in lungs of chicken infected with Pasteurella multocida
Journal
Scientific Reports
Limonin delays the progression of intervertebral disc degeneration in vivo and in vitro: the key role of the MAPK/NF-B and necroptosis pathways
Journal
The Journal of pharmacy and pharmacology
New insights into resveratrol attenuates hepatotoxicity in emamectin benzoate-exposed grass carp (Ctenopharyngodon idella) via NO system/NF-B signaling
Journal
Pesticide biochemistry and physiology
Species
Ctenopharyngodon idellus
Selenomethionine alleviates LPS-induced JNK/NLRP3 inflammasome-dependent necroptosis by modulating miR-15a and oxidative stress in chicken lungs
Journal
Metallomics : integrated biometal science
Evodiamine alleviates DEHP-induced hepatocyte pyroptosis, necroptosis and immunosuppression in grass carp through ROS-regulated TLR4/MyD88/NF-B pathway
Journal
Fish & shellfish immunology
Species
Ctenopharyngodon idella
Paraquat induces apoptosis, programmed necrosis, and immune dysfunction in CIK cells via the PTEN/PI3K/AKT axis
Journal
Fish & shellfish immunology
Species
Ctenopharyngodon idellus
Resveratrol relieves chlorothalonil-induced apoptosis and necroptosis through miR-15a/Bcl2-A20 axis in fish kidney cells
Journal
Fish & Shellfish Immunology
Roles of selenoprotein K in oxidative stress and endoplasmic reticulum stress under selenium deficiency in chicken liver
Journal
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
taVNS Alleviates Sevoflurane-Induced Cognitive Dysfunction in Aged Rats Via Activating Basal Forebrain Cholinergic Neurons
Journal
Neurochemical research
Necroptosis involved in sevoflurane-induced cognitive dysfunction in aged mice by activating NMDA receptors increasing intracellular calcium
SeMet alleviates LPS-induced eggshell gland necroptosis mediated inflammation by regulating the Keap1/Nrf2/HO-1 pathway
Journal
Archives of biochemistry and biophysics
MALT1 promotes necroptosis in stroke rat brain via targeting the A20/RIPK3 pathway
Journal
Archives of biochemistry and biophysics
Resveratrol alleviates imidaclopridinduced mitochondrial apoptosis, necroptosis, and immune dysfunction in chicken lymphocyte lines by inhibiting the ROS/MAPK
Journal
Environmental toxicology
Rutin Ameliorates Cadmium-Induced Necroptosis in the Chicken Liver via Inhibiting Oxidative Stress and MAPK/NF-κB Pathway
Journal
Biol Trace Elem Res
Apoptosis and necroptosis of mouse hippocampal and parenchymal astrocytes, microglia and neurons caused by Angiostrongylus cantonensis infection
Journal
Parasites & vectors
Revealing a potential necroptosisrelated axis (RP11138A9. 1/hsamiR985p/ZBP1) in periodontitis by construction of the ceRNA network
Journal
Journal of periodontal research
Resveratrol ameliorates myocardial ischemia/reperfusion induced necroptosis through inhibition of the Hippo pathway
Journal
Journal of bioenergetics and biomembranes
Emodin induced necroptosis in the glioma cell line U251 via the TNF-/RIP1/RIP3 pathway.
Journal
Investigational new drugs
Species
Homo sapiens, Mus musculus
Klotho attenuates angiotensin II‑induced cardiotoxicity through suppression of necroptosis and oxidative stress
The Anti-Proliferative Activity of Secondary Metabolite from the Marine Streptomyces sp. against Prostate Cancer Cells
Journal
Life (Basel, Switzerland)
Species
Marine Streptomyces sp
The role of necroptosis, apoptosis, and inflammation in fowl cholera–associated liver injury in a chicken model
Induction of complementary immunogenic necroptosis and apoptosis cell death pathways inhibits cancer metastasis and relapse