Hepatitis B Virus Induces Autophagy to Promote its Replication by the Axis of miR1923pXIAP via NFB Signaling
Journal
Hepatology (Baltimore, Md.)
RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation.
PTENα regulates mitophagy and maintains mitochondrial quality control.
CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1
BPA and low-Se exacerbate apoptosis and mitophagy in chicken pancreatic cells by regulating the PTEN/PI3K/AKT/mTOR pathway
Journal
Journal of advanced research
RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation.
Melatonin Mitigates Atrazine-Induced Renal Tubular Epithelial Cell Senescence by Promoting Parkin-Mediated Mitophagy - PMC
Journal
Research (Washington, D.C.)
Selenoprotein K protects skeletal muscle from damage and is required for satellite cells-mediated myogenic differentiation
LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss
HIF-1α-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury
Doxorubicin-polyglycerol-nanodiamond composites stimulate glioblastoma cell immunogenicity through activation of autophagy.
Journal
Acta biomaterialia
ROS Responsive Nanoparticles Encapsulated with Natural Medicine Remodel Autophagy Homeostasis in Breast Cancer
Journal
ACS applied materials & interfaces
Identification of a novel small-molecule inhibitor of miR-29b attenuates muscle atrophy - PMC
Journal
Molecular therapy. Nucleic acids
Comparative time-series multi-omics analyses suggest H1.2 involvement in anoxic adaptation and cancer resistance - PMC
Inhalation of ammonia promotes apoptosis and induces autophagy in hepatocytes via Bax/BCl-2 and m-TOR/ATG5/LC-3bII axes
Journal
The Science of the total environment
MiR-127-3p targeting CISD1 regulates autophagy in hypoxic-ischemic cortex
Cytosolic p53 Inhibits Parkin-Mediated Mitophagy and Promotes Acute Liver Injury Induced by Heat Stroke
Journal
Frontiers in immunology
RIPK3-MLKL necroptotic signalling amplifies STING pathway and exacerbates lethal sepsis - PMC
Journal
Clinical and translational medicine
Upregulation of thioredoxin contributes to inhibiting diabetic hearing impairment
Journal
Diabetes research and clinical practice
A 1, 2, 3-Triazole Derivative of Quinazoline Exhibits Antitumor Activity by Tethering RNF168 to SQSTM1/P62
Journal
Journal of medicinal chemistry
Isogarcinol inhibits nasopharyngeal carcinoma growth through mitochondria-mediated autophagic cell death
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Stimulation of Hepatic Ferritinophagy Mitigates Irp2 Depletion-Induced Anemia - PMC
Journal
Antioxidants (Basel, Switzerland)
Calenduloside E protects against myocardial ischemia-reperfusion injury induced calcium overload by enhancing autophagy and inhibiting L-type Ca2+ channels …
Journal
Biomed Pharmacother
Jianpi-Qingchang decoction alleviates ulcerative colitis by modulating endoplasmic reticulum stress-related autophagy in intestinal epithelial cells
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Species
Homo sapiens, Mus musculus
Protective Effect of Phloretin against Hydrogen Peroxide-Induced Oxidative Damage by Enhancing Autophagic Flux in DF-1 Cells - PMC
Journal
Oxidative medicine and cellular longevity
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer
Journal
Acta Pharmacologica Sinica
LW-213, a newly synthesized flavonoid, induces G2/M phase arrest and apoptosis in chronic myeloid leukemia.
Journal
Acta Pharmacologica Sinica
Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway - PMC
Journal
Respiratory research
Cadmium induces endosomal/lysosomal enlargement and blocks autophagy flux in rat hepatocytes by damaging microtubules
Journal
Ecotoxicol Environ Saf
Coenzyme Q10 ameliorates BPA-induced apoptosis by regulating autophagy-related lysosomal pathways
Journal
Ecotoxicol Environ Saf
Silver nanoparticles induced cytotoxicity in HT22 cells through autophagy and apoptosis via PI3K/AKT/mTOR signaling pathway
Journal
Ecotoxicol Environ Saf
Acute nitrite exposure-induced oxidative damage, endoplasmic reticulum stress, autophagy and apoptosis caused gill tissue damage of grass carp …
Journal
Ecotoxicology and environmental safety
Species
Ctenopharyngodon idella
Choline dehydrogenase interacts with SQSTM1 to activate mitophagy and promote coelomocyte survival in Apostichopus japonicus following Vibrio splendidus infection - PMC
Journal
Zoological research
Species
Apostichopus japonicus
Astragaloside IV-targeting miRNA-1 attenuates lipopolysaccharide-induced cardiac dysfunction in rats through inhibition of apoptosis and autophagy
Anti-inflammatory activity of carvacrol protects the heart from lipopolysaccharide-induced cardiac dysfunction by inhibiting pyroptosis via NLRP3/Caspase1/Gasdermin …
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5
Adipose-derived stem cells reduce liver oxidative stress and autophagy induced by ischemia-reperfusion and hepatectomy injury in swine.
Tannic acid attenuates intestinal oxidative damage by improving antioxidant capacity and intestinal barrier in weaned piglets and IPEC-J2 cells - PMC
Journal
Frontiers in nutrition
The Inhibition of miR-873 Provides Therapeutic Benefit in a Lipopolysaccharide-Induced Neuroinflammatory Model of Parkinson's Disease
Journal
Oxid Med Cell Longev
GPA Peptide-Induced Nur77 Localization at Mitochondria Inhibits Inflammation and Oxidative Stress through Activating Autophagy in the Intestine
Journal
Oxid Med Cell Longev
Spermidine-Eugenol Supplement Preserved Inflammation-Challenged Intestinal Cells by Stimulating Autophagy - PMC
Journal
International journal of molecular sciences
Dietary Leucine Improves Fish Intestinal Barrier Function by Increasing Humoral Immunity, Antioxidant Capacity, and Tight Junction - PMC
Journal
International journal of molecular sciences
Species
Horabagrus nigricollaris
Hesperidin Alleviates Hepatic Injury Caused by Deoxynivalenol Exposure through Activation of mTOR and AKT/GSK3/TFEB Pathways
Journal
Journal of agricultural and food chemistry
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
DJ-1 Regulates Microglial Polarization Through P62-Mediated TRAF6/IRF5 Signaling in Cerebral Ischemia-Reperfusion
Journal
Front Cell Dev Biol
Fangchinoline inhibits the PEDV replication in intestinal epithelial cells via autophagic flux suppression - PMC
Journal
Frontiers in microbiology
Activation of p62-NRF2 Axis Protects against Doxorubicin-Induced Ferroptosis in Cardiomyocytes: A Novel Role and Molecular Mechanism of Resveratrol
Journal
The American journal of Chinese medicine
Hyperoside Protects Human Umbilical Vein Endothelial Cells Against Anticardiolipin Antibody-Induced Injury by Activating Autophagy
Oat beta-glucan reduces colitis by promoting autophagy flux in intestinal epithelial cells via EPHB6-TFEB axis - PMC
Journal
Frontiers in pharmacology
Species
Homo sapiens, Mus musculus
MOB1A regulates glucose deprivation-induced autophagy via IL6-STAT3 pathway in gallbladder carcinoma
5-Heptadecylresorcinol Ameliorates Obesity-Associated Skeletal Muscle Mitochondrial Dysfunction through SIRT3-Mediated Mitophagy
Journal
Journal of agricultural and food chemistry
p53 SUMOylation Mediates AOPP-Induced Endothelial Senescence and Apoptosis Evasion
Journal
Frontiers in cardiovascular medicine
Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection
Macrophages-derived p38α promotes the experimental severe acute pancreatitis by regulating inflammation and autophagy
Journal
International Immunopharmacology
pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway
Journal
International immunopharmacology
Exercise pretreatment alleviates neuroinflammation and oxidative stress by TFEB-mediated autophagic flux in mice with ischemic stroke
Journal
Experimental neurology
Corynoxine B ameliorates HMGB1-dependent autophagy dysfunction during manganese exposure in SH-SY5Y human neuroblastoma cells.
Journal
Food and chemical toxicology
Berberine mitigates IL-21/IL-21R mediated autophagic influx in fibroblast-like synoviocytes and regulates Th17/Treg imbalance in rheumatoid arthritis.
Journal
Apoptosis : an international journal on programmed cell death
Autophagy induced by Vip3Aa has a pro-survival role in Spodoptera frugiperda Sf9 cells
Species
Spodoptera frugiperda
Lactobacillus rhamnosus attenuates intestinal inflammation induced by Fusobacterium nucleatum infection by restoring the autophagic flux
Increased expression of sterol regulatory element binding protein-2 alleviates autophagic dysfunction in NAFLD.
Journal
International Journal of Molecular Medicine
Parecoxib alleviates the motor behavioral decline of aged rats by ameliorating mitochondrial dysfunction in the substantia nigra via COX-2/PGE2 pathway inhibition
Regulation of SREBP-2 intracellular trafficking improves impaired autophagic flux and alleviates endoplasmic reticulum stress in NAFLD
Journal
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
Eucalyptol relieves imidacloprid-induced autophagy through the miR-451/Cab39/AMPK axis in Ctenopharyngodon idellus kidney cells †
Journal
Aquatic toxicology (Amsterdam, Netherlands)
Species
Ctenopharyngodon idellus
p-TAK1 acts as a switch between myoblast proliferation phase and differentiation phase in mdx mice via regulating HO-1 expression
Journal
European journal of pharmacology
UBE2T is upregulated, predicts poor prognosis, and promotes cell proliferation and invasion by promoting epithelial-mesenchymal transition via inhibiting autophagy in an AKT/mTOR dependent manner in ovarian cancer
Journal
Cell cycle (Georgetown, Tex.)
Exogenous H2S alleviates senescence of glomerular mesangial cells through up-regulating mitophagy by activation of AMPK-ULK1-PINK1-parkin pathway in mice
Journal
Biochimica et biophysica acta. Molecular cell research
Hyperoside attenuates pregnancy loss through activating autophagy and suppressing inflammation in a rat model
BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment
Journal
The Journal of steroid biochemistry and molecular biology
Urolithin A suppresses tumor progression and induces autophagy in gastric cancer via the PI3K/Akt/mTOR pathway
Journal
Drug development research
Inhibition of Klf10 Attenuates Oxidative Stress-Induced Senescence of Chondrocytes via Modulating Mitophagy - PMC
Journal
Molecules (Basel, Switzerland)
Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma
Journal
BMC Complement Med Ther
Thiram exposure: Disruption of the blood-testis barrier and altered apoptosis-autophagy dynamics in testicular cells via the Bcl-2/Bax and mTOR/Atg5/p62 pathways in
Journal
Pesticide biochemistry and physiology
New insights into resveratrol attenuates hepatotoxicity in emamectin benzoate-exposed grass carp (Ctenopharyngodon idella) via NO system/NF-B signaling
Journal
Pesticide biochemistry and physiology
Species
Ctenopharyngodon idellus
Cr(VI)-Induced Autophagy Protects L-02 Hepatocytes from Apoptosis Through the ROS-AKT-mTOR Pathway.
Journal
Cellular physiology and biochemistry
Inhibition of miRNA-1-Mediated Inflammation and Autophagy by Astragaloside IV Improves Lipopolysaccharide-Induced Cardiac Dysfunction in Rats
Journal
Journal of inflammation research
Cineole regulates Wnt/β-catenin pathway through Nrf2/keap1/ROS to inhibit bisphenol A-induced apoptosis, autophagy inhibition and immunosuppression of grass …
Journal
Fish & shellfish immunology
Species
Ctenopharyngodon idellus
The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential role for enhanced autophagy
Journal
Psychopharmacology
CF101 alleviates OA progression and inhibits the inflammatory process via the AMP/ATP/AMPK/mTOR axis
Long Noncoding RNA ADAMTS9-AS2 Inhibits the Proliferation, Migration, and Invasion in Bladder Tumor Cells
NOD2 inhibits the proliferation of esophageal adenocarcinoma cells through autophagy
Journal
Journal of cancer research and clinical oncology
Lipopolysaccharide promotes NLRP3 inflammasome activation by inhibiting TFEB-mediated autophagy in NRK-52E cells
Journal
Molecular immunology
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells - PMC
Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy - PMC
Journal
Analytical cellular pathology (Amsterdam)
Long non-coding RNA ADAMTS9-AS1 exacerbates cell proliferation, migration, and invasion via triggering of the PI3K/AKT/mTOR pathway in hepatocellular …
The potential benefits of PGC-1 in treating Alzheimer's disease are dependent on the integrity of the LLKYL L3 motif: Effect of regulating mitochondrial axonal
Journal
Experimental gerontology
Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis
Journal
Toxicology and Applied Pharmacology
TM9SF1 knockdown decreases inflammation by enhancing autophagy in a mouse model of acute lung injury - PMC
Cardioprotection of cortistatin against isoproterenol-induced myocardial injury in rats
Journal
Annals of Translational Medicine
Rosmarinic acid activates the Ras/Raf/MEK/ERK signaling pathway to regulate CD8+ T cells and autophagy to clear Chlamydia trachomatis in reproductive tract
Journal
Molecular immunology
The effect of aerobic exercise on the lipophagy of adipose tissue in obese male mice
Journal
Chemistry and physics of lipids
Protective effect of phenylpropionamides in the seed of Cannabis Sativa L. on Parkinson's disease through autophagy
Influence of Autophagy Inhibition on Lung Adenocarcinoma Cell Migration and Invasion Ability, and Efficacy of Gefitinib
Journal
Technol Cancer Res Treat
Sodium butyrate induces autophagic apoptosis of nasopharyngeal carcinoma cells by inhibiting AKT/mTOR signaling.
Journal
Biochemical and biophysical research communications
GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal
Dexmedetomidine mitigates neuroinflammation and improves early postoperative neurocognitive dysfunction in rats by enhancing autophagy
Journal
Journal of neurophysiology
Downregulation of AMPK dependent FOXO3 and TFEB involves in the inhibition of autophagy in diabetic cataract
Ononin alleviates DSS-induced colitis through inhibiting NLRP3 inflammasome via triggering mitophagy - PMC
Journal
Immunity, inflammation and disease
Functional identification of Bombyx mori Atg13 in autophagy
Journal
Arch Insect Biochem Physiol
Species
Bombyx mori Linnaeus
Hinokitiol Inhibits the Viability of Oral Squamous Carcinoma Cells by Inducing Apoptosis and Autophagy
Journal
Anticancer research
Heat exposure affected the reproductive performance of pregnant mice: Enhancement of autophagy and alteration of subcellular structure in the corpus luteum.
Journal
Reproductive biology
ChemR23 activation attenuates cognitive impairment in chronic cerebral hypoperfusion by inhibiting NLRP3 inflammasome-induced neuronal pyroptosis - PMC
Journal
Cell death & disease
Species
Rattus norvegicus, Homo sapiens
Blockage of Nrf2 and autophagy by L-selenocystine induces selective death in Nrf2-addicted colorectal cancer cells through p62-Keap-1-Nrf2 axis - PMC
Journal
Cell death & disease